CAS No.: 77-59-8
Tomatidine/番茄碱 Catalog No. CSN12111
Synonyms: 5alpha-Tomatidan-3beta-ol;番茄碱
Tomatidine, a natural product isolated and purified from the fruits of Lycopersicon esculentum Mill., shows antibiotic activity against small-colony variants of S. aureus, significantly suppresses the activity of ACAT and leads to reduction of atherogenesis. It also inhibits the phosphorylation of ERK, Akt, and the nuclear content of NF-κB.
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纯度 & 质量文件
批次:
靶点选择性
生物活性
- 描述
- 参考文献
- [1] Chagnon F, Guay I, et al. Unraveling the structure-activity relationship of tomatidine, a steroid alkaloid with unique antibiotic properties against persistent forms of Staphylococcus aureus. Eur J Med Chem. 2014 Jun 10;80:605-20.
- [2] Dyle MC, Ebert SM, et al. Systems-based discovery of tomatidine as a natural small molecule inhibitor of skeletal muscle atrophy. J Biol Chem. 2014 May 23;289(21):14913-24.
实验方案
- 计算器
- 储存液制备
技术信息
| CAS号 | 77-59-8 | 储存条件 |
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| 分子式 | C27H45NO2 | 运输 | 蓝冰 | |
| 分子量 | 415.65 | 别名 | 5alpha-Tomatidan-3beta-ol;番茄碱 |
