CAS No.: 622370-35-8
Tradipitant Catalog No. CSN19815
Synonyms: VLY-686;LY686017
Tradipitant is the 2nd generation neurokinin-1 receptor antagonist, which showed activity in preclinical anxiety models.
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纯度 & 质量文件
批次:
靶点选择性
生物活性
- 描述
- 临床研究
NCT号 适应症或疾病 临床期 招募状态 预计完成时间 地点 NCT02970968 Gastroparesis Phase 2 Recruiting December 2018 - NCT03568331 Atopic Dermatitis Phase 3 Recruiting December 2019 - NCT02621385 Healthy Volunteers Phase 1 Completed - Switzerland ... more >> Vanda Investigational Site Arzo, Switzerland, 6864 Collapse << - 更多
- 参考文献
- [1] Gackenheimer SL, Gehlert DR. In vitro and ex vivo autoradiography of the NK-1 antagonist [³H] -LY686017 in Guinea pig brain. Neuropeptides. 2011 Apr;45(2):157-64.
- [2] Tauscher J, Kielbasa W, et al. Development of the 2nd generation neurokinin-1 receptor antagonist LY686017 for social anxiety disorder. Eur Neuropsychopharmacol. 2010 Feb;20(2):80-7.
实验方案
- 计算器
- 储存液制备
技术信息
| CAS号 | 622370-35-8 | 储存条件 |
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| 分子式 | C28H16ClF6N5O | 运输 | 蓝冰 | |
| 分子量 | 587.90 | 别名 | VLY-686;LY686017 |
