生物活性

• 描述Valganciclovir, the L-valyl ester of ganciclovir, is actually a prodrug for ganciclovir and an antiviral medication used to treat cytomegalovirus infections.
• 临床研究

• NCT号	适应症或疾病	临床期	招募状态	预计完成时间	地点
  NCT02227641	Patients Undergoing Allogeneic... more >> Stem Cell Transplantation Collapse <<	Phase 1 Phase 2	Unknown	March 2017	Germany ... more >> Medical Center Augsburg Recruiting Augsburg, Germany, 86156 Contact: Christoph Schmid, MD, PhD    0049 821 4002736       Principal Investigator: Christoph Schmid, MD, PhD          Charité University Hospital Berlin Recruiting Berlin, Germany, 13353 Contact: Armin H Gerbitz, MD, PhD    ++49 30 450565256    armin.gerbitz@charite.de    Contact: Lutz Uharek, MD, PhD       lutz.uharek@charite.de    Sub-Investigator: Lutz Uharek, MD, PhD          Principal Investigator: Armin Gerbitz, MD, PhD          Universitiy Hospital Erlangen Recruiting Erlangen, Germany, 91054 Contact: Anita Kremer, MD, PhD    ++49 9131 8543183    anita.kremer@uk-erlangen.de    Contact: Bernd Spriewald, MD, PhD    ++49 9131 8543116    bernd.spriewald@uk-erlangen.de    Sub-Investigator: Katja San Niccolo, MD          University of Mainz Recruiting Mainz, Germany, 55131 Contact: Eva Wagner, MD          Principal Investigator: Eva Wagner, MD          University of Munich LMU Recruiting Munich, Germany, 81377 Contact: Johanna Tischer, MD    0049 89 70954240       Principal Investigator: Johanna Tischer, MD          University of Regensburg Not yet recruiting Regensburg, Germany, 93053 Contact: Ernst Holler, MD, PhD    0049 941 9445570       Principal Investigator: Ernst Holler, MD, PhD Collapse <<
  NCT02188719	Liver Transplantation	Phase 1	Recruiting	January 2022	United States, California ... more >> University of California, San Francisco Recruiting San Francisco, California, United States, 94143 Contact: Monique Koenigsberg    415-502-3016    Monique.Koenigsberg@ucsf.edu    Principal Investigator: Sandy Feng, MD, PhD          United States, Illinois Northwestern University Recruiting Chicago, Illinois, United States, 55905 Contact: Patrice Al-Saden    312-503-1058    palsaden@northwestern.edu    Principal Investigator: Josh Levitsky, MD          United States, Minnesota Mayo Clinic Recruiting Rochester, Minnesota, United States, 55905 Contact: Julie Gecox Hanson, CCRP    507-293-6592    Gecox.Julie@mayo.edu    Principal Investigator: Timucin Taner, MD, PhD Collapse <<
  NCT00078559	Kidney Transplantation ... more >> Kidney Disease Collapse <<	Phase 1 Phase 2	Completed	-	United States, Wisconsin ... more >> University of Wisconsin - Department of Medicine Madison, Wisconsin, United States, 53792-1735 Collapse <<

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• 参考文献

• [1] O'Brien S, Ravandi F, et al. Valganciclovir prevents cytomegalovirus reactivation in patients receiving alemtuzumab-based therapy. Blood. 2008 Feb 15;111(4):1816-9.

  [2] Sugawara M, Huang W, et al. Transport of valganciclovir, a ganciclovir prodrug, via peptide transporters PEPT1 and PEPT2. J Pharm Sci. 2000 Jun;89(6):781-9.