CAS No.: 3371-85-5
Voacamine/老刺木胺 Catalog No. CSN20008
Synonyms: NSC 82591;老刺木胺
Voacamine, isolated from the plant Tabernaemontana coronaria, is an antiprotozoal agent effective against a large array of trypanosomatid parasites including Indian strain of Leishmania donovani and Brazilian strains of Leishmania amazonensis and Trypanosoma cruzi by inhibiting the relaxation activity of topoisomerase IB.
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纯度 & 质量文件
批次:
靶点选择性
生物活性
- 描述
- 参考文献
- [1] Chowdhury SR, Kumar A, et al. Voacamine alters Leishmania ultrastructure and kills parasite by poisoning unusual bi-subunit topoisomerase IB. Biochem Pharmacol. 2017 May 5. pii: S0006-2952(17)30251-4.
- [2] Condello M, Multari G, et al. High-performance thin-layer chromatography for the evaluation of voacamine intracellular concentration related to its cytotoxic effect. J Pharm Biomed Anal. 2015 Nov 10;115:467-74.
实验方案
- 计算器
- 储存液制备
技术信息
| CAS号 | 3371-85-5 | 储存条件 |
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| 分子式 | C43H52N4O5 | 运输 | 蓝冰 | |
| 分子量 | 704.90 | 别名 | NSC 82591;老刺木胺 |
