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Proteasome
| 货号 | 产品名 | CAS号 | 信息 |
|---|---|---|---|
| CSN22527 | TY-51469 | 603987-59-3 | TY-51469 is a chymase inhibitor with IC50s for simian and human chymases of 0.4 and 7.0 nM, respectively. |
| CSN25332 | 3,5-Bis(3,4-dichlorobenzylidene)piperidin-4-one | 145888-79-5 | PTP1B-IN-9 is a ubiquitin-proteasome system (UPS)-stressor. It inhibits ubiquitin-mediated protein degradation upstream of the 20S proteasomal catalytic activites, with anticancer activity. |
| CSN11436 | MG-132 | 133407-82-6 | MG-132 is an inhibitor of proteasome (IC50 = 100 nM) and calpain (IC50 = 1.2 nM). |
| CSN19716 | Marizomib | 437742-34-2 | Marizomib, a natural product isolated and purified from marine bacteria Salinispora tropica and Salinispora arenicola, inhibits 20S proteasome to overcome compensatory hyperactivation in multiple myeloma and solid tumour patients. |
| CSN22831 | Gliotoxin | 67-99-2 | Gliotoxin is an inhibitor of 20S proteasome and acts as immunosuppressive agent. |
| CSN15770 | Epoxomicin | 134381-21-8 | Epoxomicin is a potent anti-tumor agent isolated from Actinomycetes that is used as a selective and irreversible inhibitor of the 20S proteasome. |
| CSN22376 | Clasto-Lactacystin β-lactone | 154226-60-5 | Clasto-Lactacystin β-lactone, a natural active metabolite of lactacystin, which is a metabolite of Streptomyces, acts as an irreversible 20S proteasome inhibitor. |
| CSN16303 | Celastrol | 34157-83-0 | Celastrol is an inhibitor of HSP90 with antioxidant and anti-inflammatory activities. |
| CSN10115 | Bortezomib | 179324-69-7 | Bortezomib is an inhibitor of 20S proteasome with Ki of 0.6 nM. |
| CSN20399 | Aclarubicin HCl | 75443-99-1 | Aclarubicin HCl is the HCl salt of aclarubicin, an oligosaccharide anthracycline antineoplastic antibiotic isolated from the bacterium Streptomyces galilaeus. |
