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Proteasome

Proteasome

货号 产品名 CAS号 信息
CSN22527 TY-51469 603987-59-3 TY-51469 is a chymase inhibitor with IC50s for simian and human chymases of 0.4 and 7.0 nM, respectively.
CSN25332 3,5-Bis(3,4-dichlorobenzylidene)piperidin-4-one 145888-79-5 PTP1B-IN-9 is a ubiquitin-proteasome system (UPS)-stressor. It inhibits ubiquitin-mediated protein degradation upstream of the 20S proteasomal catalytic activites, with anticancer activity.
CSN11436 MG-132 133407-82-6 MG-132 is an inhibitor of proteasome (IC50 = 100 nM) and calpain (IC50 = 1.2 nM).
CSN22831 Gliotoxin 67-99-2 Gliotoxin is an inhibitor of 20S proteasome and acts as immunosuppressive agent.
CSN15770 Epoxomicin 134381-21-8 Epoxomicin is a potent anti-tumor agent isolated from Actinomycetes that is used as a selective and irreversible inhibitor of the 20S proteasome.
CSN22376 Clasto-Lactacystin β-lactone 154226-60-5 Clasto-Lactacystin β-lactone, a natural active metabolite of lactacystin, which is a metabolite of Streptomyces, acts as an irreversible 20S proteasome inhibitor.
CSN16303 Celastrol 34157-83-0 Celastrol is an inhibitor of HSP90 with antioxidant and anti-inflammatory activities.
CSN10115 Bortezomib 179324-69-7 Bortezomib is an inhibitor of 20S proteasome with Ki of 0.6 nM.
CSN20399 Aclarubicin HCl 75443-99-1 Aclarubicin HCl is the HCl salt of aclarubicin, an oligosaccharide anthracycline antineoplastic antibiotic isolated from the bacterium Streptomyces galilaeus.
CSN22627 (R)-MG 132 1211877-36-9 (R)-MG132 can act as an inhibitor of proteasome and be used in ubiquitination assay.
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