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Functions as 15-oxo-prostaglandin 13-reductase and acts on 15-keto-PGE1, 15-keto-PGE2, 15-keto-PGE1-alpha and 15-keto-PGE2-alpha with highest activity towards 15-keto-PGE2. Overexpression represses transcriptional activity of PPARG and inhibits adipocyte differentiation (By similarity).

PTGR

货号 产品名 CAS号 信息
CSN27726 PTGR2-IN-22 349093-44-3 PTGR2-IN-1 is a potent PTGR2 inhibitor with IC50 value of ~0.7μM. It increases 15-keto-PGE2-dependent PPARγ transcriptional activity.
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