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Quinone reductase type 1 (QR1) reduces quinines to the non-toxic hydroquinone. Quinone reductase type 2 (QR2) catalyzes the reduction of adrenochrome.

QR

货号 产品名 CAS号 信息
CSN14763 Xanthohumol D 274675-25-1 Xanthohumol D, a natural product isolated and purified from the herbs of Humulus lupulus, is a potent inhibitor of quinone reductase-2 (QR-2) with IC50 of 110μM.
CSN14649 Tigloylgomisin H 66069-55-4 Tigloylgomisin H, a natural product isolated and purified from the fruits of Schisandra chinensis, can significantly induce quinone reductase (QR) activity in Hepa1c1c7 mouse hepatocarcinoma cells. It functions as a monofunctional inducer that specifically upregulates phase II enzymes through the Nrf2-ARE pathway, thus represents a potential liver cancer prevention agent.
CSN24723 S29434 874484-20-5 S29434 is a potent, nanomolar inhibitor of QR2 with IC50 of 5-16 nM at different organizational levels.
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