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Quinones
| 货号 | 产品名 | CAS号 | 信息 |
|---|---|---|---|
| CSN17088 | Xanthopurpurin | 518-83-2 | Xanthopurpurin is a natural product isolated and purified from the roots of Rubia cordifolia, effectively inhibits rotavirus multiplication by promoting virus-induced apoptosis in MA-104 cells, and shows mainly strong inhibition of collagen-induced platelet aggregation. |
| CSN20034 | Thymoquinone | 490-91-5 | Thymoquinone is a phytochemical compound that acts as an angiogenesis inhibitor. Thymoquinone possesses potential analgesic, anticonvulsant, and anticancer properties in vitro. |
| CSN26148 | (S)-2,2',4,4',5,5'-Hexahydroxy-7,7'-dimethyl-[1,1'-bianthracene]-9,9',10,10'-tetraone | 602-06-2 | Skyrin is a fungal bisanthroquinone. It exhibits functional glucagon antagonism by uncoupling the glucagon receptor from adenylate cyclase activation in rat liver membranes. |
| CSN13928 | Sennoside C | 37271-16-2 | Sennoside C is a natural product isolated and purified from the leaves of Cassia angustifolia. |
| CSN16471 | Sennoside A | 81-27-6 | Sennoside A, a kind of irritant laxative isolated from rhei rhizome, causes purgative actions in the intestine. |
| CSN15180 | Salvisyrianone | 250691-57-7 | Salvisyrianone is a natural product isolated and purified from the herbs of Salvia syriaca. |
| CSN15182 | Rubioncolin C | 132242-52-5 | Rubioncolin C is a natural product isolated and purified from plants. |
| CSN15308 | Rubianthraquinone | 644967-44-2 | Rubianthraquinone is a natural product isolated and purified from the roots of Rubia yunnanensis. |
| CSN19356 | Rhein | 478-43-3 | Rhein is a lipophilic anthraquinone extensively found in medicinal herbs, and has many pharmacological effects, including epatoprotective, nephroprotective, anti-inflammatory, antioxidant, anticancer, and antimicrobial activities. Rhein Inhibits Autophagy in Rat Renal Tubular Cells by Regulation of AMPK/mTOR Signaling. |
| CSN13528 | Physcion 8-O-β-D-glucopyranoside | 23451-01-6 | Physcion 8-O-beta-d-monoglucoside is a natural product. |
| CSN13997 | Phyllostine | 27270-89-9 | Phyllostine, a natural product isolated and purified from Pencillium urticae, appears to be their more immediate precursor, since PCMB-treated extracts of J2 converted Phyllostine but not isoepoxydon to these metabolites. |
| CSN19333 | Oxymatrine | 16837-52-8 | Oxymatrine is a quinolizidine alkaloid extracted from the root of Sophora flavescens, which is used for the treatment of viral hepatitis, cancer, viral myocarditis, gastrointestinal hemorrhage and skin diseases. |
| CSN13536 | Obtusin | 70588-05-5 | Obtusin is a natural product isolated and purified from Semen Cassiae. |
| CSN20571 | Menaquinone-7 | 2124-57-4 | Menaquinone-7 is a long-chain menaquinone member of Vitamin K2, showing anti-cancer activity. |
| CSN20565 | Menaquinone-4 | 863-61-6 | Menaquinone-4 is the most important member of short-chain menaquinones in Vitamine K2. |
| CSN11340 | Lucidin | 478-08-0 | Lucidin is a natural component of Rubia tinctorum L. |
| CSN11267 | Lapachol | 84-79-7 | Lapachol is a naturally occuring phenolic compound isolated from the bark of the lapacho tree, with anti-inflammatory, analgesic and antibiotic properties. |
| CSN19714 | Juglone | 481-39-0 | Juglone significantly inhibits the proliferation and induce the apoptosis of SiHa cells and Caski cells, stimulates suicidal erythrocyte death or eryptosis at least in part by upregulation of ceramide abundance, energy depletion and activation of PKC, and prevents high-fat diet-induced liver injury and nerve inflammation in mice through inhibition of inflammatory cytokine secretion, NF-kappa B activation and endotoxin production. It's a natural product isolated and purified from the barks of Juglans regia L.. |
| CSN20203 | Hypocrellin B | 123940-54-5 | Hypocrellin B, a natural product isolated and purified from Hypocrella bambusae, has sonodynamic action to induce mitochondrial damage, survival inhibition, apoptosis and inhibit adhesion and migration of cancer cells. |
| CSN12612 | Hypericin | 548-04-9 | Hypericin, a natural product isolated and purified from the herb of Hypericum perforatum L., is a photosensitive antiviral with anticancer and antidepressant agent derived from Hypericum perforatum. |
| CSN13964 | Aurantio-obtusin | 67979-25-3 | GlucoAurantio-obtusin, a natural product isolated and purified from the seeds of Cassia obtusifolia L., possesses hypotensive and hypolipidemic effects. |
| CSN13340 | Ethyl(1-Hydroxy-4-Oxocyclohexa-2,5-Dien-1-Yl)acetate | 60263-06-1 | Ethyl(1-hydroxy-4-oxocyclohexa-2,5-dien-1-yl)acetate is a natural product isolated and purified from the herbs of Senecio scandens. |
| CSN13980 | Emodin-8-glucoside | 23313-21-5 | Emodin-8-beta-D-glucoside, a natural product isolated and purified from the root and rhizome of Rheum palmatum L., functions to protect from focal cerebral injury induced by ischemia and reperfusion and directly stimulates cell proliferation and differentiation of osteoblasts. |
| CSN17013 | β,β-Dimethylacrylshikonin | 24502-79-2 | Dimethylacrylshikonin, a natural product isolated and purified from the roots of Lithosperraum erythrorhizon Sieb. et Zucc. with anti-proliferate activity, is a promising agent for developing an improved strategy for radiotherapy against tumors. |
| CSN21397 | Deoxylapachol | 3568-90-9 | Deoxylapachol induced fungal cell wall stress and inhibited fungal growth. |
| CSN14072 | 2,2-Dimethyl-2H-benzo[g]chromene-5,10-dione | 15297-92-4 | Dehydro-alpha-lapachone, a natural product isolated and purified from the roots of Radermachera sinica with antifungal, antibacterial and antitumor activities, can be as a potential drug for reducing cancer metastasis and can inhibit vessel regeneration, interfere with vessel anastomosis, and limit plexus formation in zebrafish. |
| CSN10741 | Damnacanthal | 477-84-9 | Damnacanthal, a natural product isolated and purified from the fruit of Morinda citrifolia Linn., possesses anti-cancer property and can treat or prevent hepatocellular carcinoma through its inhibitory effects on the HGF/c-Met axis. |
| CSN14045 | 1,3,8-Trihydroxy-6-(hydroxymethyl)anthracene-9,10-dione | 481-73-2 | Citreorosein, a cAMP phosphodiesterase inhibitor isolated and purified from the root and rhizome of Rheum palmatum L., has anti-inflammatory effect, inhibits proinflammatory cytokines production through the inhibition of both MAPKs and AKT-mediated IκB kinase (IKK) phosphorylation and subsequent inhibition of transcription factor NF-κB activation. |
| CSN14045 | 1,3,8-Trihydroxy-6-(hydroxymethyl)anthracene-9,10-dione | 481-73-2 | Citreorosein, a cAMP phosphodiesterase inhibitor isolated and purified from the root and rhizome of Rheum palmatum L., has anti-inflammatory effect, inhibits proinflammatory cytokines production through the inhibition of both MAPKs and AKT-mediated IκB kinase (IKK) phosphorylation and subsequent inhibition of transcription factor NF-κB activation. |
| CSN17313 | Chrysophanol | 481-74-3 | Chrysophanol, a natural anthraquinone isolated from Dianella longifolia, is an EGFR/mTOR pathway inhibitor. |
| CSN14572 | Chrysophanol 8-O-glucoside | 13241-28-6 | Chrysophanol 8-O-glucoside, a natural product isolated and purified from the roots of Rheum with potent inhibitory effect on collagen- and thrombin-induced platelet aggregation, only inhibits platelet phosphatidylserine exposure, but not exerts direct inhibition on intrinsic factors, suggests that it may be of therapeutic benefit for the prevention of platelet-related cardiovascular diseases. |
| CSN13535 | Chrysoobtusin | 70588-06-6 | Chrysoobtusin is a natural product isolated and purified from Semen Cassiae. |
| CSN20328 | Chlorobenzoyl Mansonone G | 2109805-85-6 | Chlorobenzoyl mansonone G, a derivative of mansonone G isolated from Mansonia gagei heartwoods, may have beneficial applications in the control of obesity through the suppression of PPARγ-induced adipocyte differentiation and lipid accumulation. |
| CSN13601 | β,β-Dimethylacrylalkannin | 34539-65-6 | beta,beta-Dimethylacrylalkannin, a natural product isolated and purified from the roots of Lithospermum erythrorhizon with radical scavenging activity, can be potential therapeutics against tumor cell growth because of its unique DNA damaging abilities additional to enzyme inhibition similar to those of doxorubicin, shows remarkable cytotoxic activity against HT-29, MDA-MB-231 and PC-3 cell lines, comparable or stronger than the other compounds and positive control CPT-11 (CAMPTOSTAR®, irinotecan) with IC50 values in between 0.1uM and 1uM and it has great potential as topo I inhibitors compared to other compounds and CPT-11, with 2-3uM inhibition value, and exhibits inhibitory activities on PTP1B with IC50 values of 0.36±0.08 μMol·L-1. |
| CSN14573 | Averantin | 5803-62-3 | Averantin, a metabolite of Aspergillus sp. associated with Panax notoginseng, exhibits antifungal activity against Fusariumsolani, pathogenic fungus of P. notoginseng, with minimum inhibitory concentrations (MICs) of 16-32 ug/mL, and shows antibacterial activity against Bacillussubtilis with MICs of 16-32 ug/mL. |
| CSN14071 | α-Lapachone | 4707-33-9 | alpha-Lapachone, a natural product isolated and purified from the barks of Catalpa ovata, does not induce H₂O₂ formmation but shows an approximately the same trypanocidal activity of beta-lapachone. |
| CSN10252 | Aloin B | 28371-16-6 | Aloin B is one isomer of aloin, which is a physiologically active anthraquinone present in aloe. |
| CSN17350 | Aloe-emodin | 481-72-1 | Aloe-emodin, a natural product isolated and purified from the root of Rheum palmatum L. with a specific in vitro and in vivo anti-neuroectodermal tumor activity, reduces the toxicity and ROS induced by both monomeric and oligomeric Aβ species, appears to have some protective effect not only against hepatocyte death but also on the inflammatory response subsequent to lipid peroxidation and has a strong non-carcinogenic stimulant-laxative action when applied to the skin, although it may increase the carcinogenicity of some kind of radiation. Aloe-Emodine dose-dependently inhibited cleavage activity of the 3CLpro with IC50 value of 366μM in the cell-based assay. |
| CSN19793 | (-)-Alkannin | 517-88-4 | Alkannin, a natural product isolated and purified from the roots of Lithosperraum erythrorhizon Sieb. et Zucc., can suppress the cell viability, adhesion, invasion and migratory ability of MGC-803 cells through TLR2- or NF-κB-mediated pathway. |
| CSN13010 | 9-Hydroxy-alpha-Lapachone | 22333-58-0 | 9-Hydroxy-alpha-lapachone, a natural product isolated and purified from the herbs of Catalpa ovata, exhibits potent inhibitory activity against H. pylori Cystathionine gamma-synthase, with IC(50) values of 4.64 mM. |
| CSN14762 | 6-Hydroxyrubiadin | 87686-86-0 | 6-Hydroxyrubiadin is a natural product isolated and purified from the roots of Rubia cordifolia L.. |
| CSN14687 | 2-Methoxystypandrone | 85122-21-0 | 2-Methoxystypandrone, a natural product isolated and purified from the roots of Polygonum cuspidatum, displays an immunomodulatory effect in a cellular model, specifically inhibits JAK and IKKβ kinase activities, blocks inflammatory responses by impairing NF-κB signaling to limit the inflammation and oxidative stress for preservation of BBB integrity, concomitantly promotes neurodevelopmental protein expression and endogenous neurogenesis through inactivation of GSK3β to enhance β-catenin signaling for upexpression of neuroprotective genes and proteins, and has anti-osteoclastogenic effect, could reflect the block of RANKL-induced association of TRAF6-TAK1 complexes with consequent decrease of IkappaB-mediated NF-kappaB and mitogen-activated protein kinases-mediated c-Fos activation pathways and suppression of NFATc1 and other gene expression, essential for bone resorption. |
| CSN14925 | 2-CarbaMoyl-3-Hydroxy-1,4-Naphthoquinone | 103646-20-4 | 2-CarbaMoyl-3-hydroxy-1,4-naphthoquinone is a natural product isolated and purified from plants. |
| CSN13009 | 2,6-Dimethoxy-1-Acetonylquinol | 2215-96-5 | 2,6-Dimethoxy-1-acetonylquinol, a natural product isolated and purified from the barks of Ailanthus altissima, shows varying degrees of in vitro antimalarial activity against Plasmodium falciparum and is devoid of significant cytotoxicity to the human oral epidermoid KB cancer cell line. |
| CSN18689 | 2,6-Dimethoxy-1,4-benzoquinone | 530-55-2 | 2,6-Dimethoxy-1,4-benzoquinone exhibits strong antibacterial activities against S. pyogenes, S. mitis, and S. mutans with MIC values of 7.8, 7.8, and 15.6 ug/mL, and MBC values of 7.8, 7.8, and 31.2 ug/mL respectively. It also produces genotoxic effects in patients taking dimethophrine, it's a natural product isolated and purified from the barks of Liriodendron tulipifera. |
| CSN15309 | 1-O-Methylnataloe-Emodin | 103392-51-4 | 1-O-Methylnataloe-emodin is a natural product isolated and purified from plants. |
| CSN14201 | 1-Hydroxy-2-methylanthraquinone | 6268-09-3 | 1-Hydroxy-2-methylanthraquinone is a natural product isolated and purified from the roots of Rubia cordifolia with promising larvicidal activity. |
| CSN15307 | 1,5,15-Trimethylmorindol | 942609-65-6 | 1,5,15-Tri-O-methylmorindol, a natural product isolated and purified from the herbs of Morinda citrifolia, has effects against the Epstein-Barr virus early antigen (EBV-EA) activation induced by TPA. |
