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Quinones

Quinones

货号 产品名 CAS号 信息
CSN17088 Xanthopurpurin 518-83-2 Xanthopurpurin is a natural product isolated and purified from the roots of Rubia cordifolia, effectively inhibits rotavirus multiplication by promoting virus-induced apoptosis in MA-104 cells, and shows mainly strong inhibition of collagen-induced platelet aggregation.
CSN20034 Thymoquinone 490-91-5 Thymoquinone is a phytochemical compound that acts as an angiogenesis inhibitor. Thymoquinone possesses potential analgesic, anticonvulsant, and anticancer properties in vitro.
CSN26148 Skyrin 602-06-2 Skyrin is a fungal bisanthroquinone. It exhibits functional glucagon antagonism by uncoupling the glucagon receptor from adenylate cyclase activation in rat liver membranes.
CSN13928 Sennoside C 37271-16-2 Sennoside C is a natural product isolated and purified from the leaves of Cassia angustifolia.
CSN16131 Sennoside B 128-57-4 Sennoside B inhibits PDGF-stimulated cell proliferation, it's a kind of irritant laxative isolated from rhei rhizome and leaves of Cassia angustifolia..
CSN16471 Sennoside A 81-27-6 Sennoside A, a kind of irritant laxative isolated from rhei rhizome, causes purgative actions in the intestine.
CSN15182 Rubioncolin C 132242-52-5 Rubioncolin C is a natural product isolated and purified from plants.
CSN17087 Rubiadin 117-02-2 Rubiadin, a natural product isolated and purified from the roots of Rubia cordifolia with hepatoprotective effects against carbon tetrachloride (CCl 4 )-induced hepatic damage in rats and potent antioxidant property, can prevent lipid peroxidation induced by FeSO4 and t-butylhydroperoxide (t-BHP) in a dose dependent manner, and decrease bone loss through the inhibition of osteoclast formation, differentiation and bone resorption.
CSN19356 Rhein 478-43-3 Rhein is a lipophilic anthraquinone extensively found in medicinal herbs, and has many pharmacological effects, including epatoprotective, nephroprotective, anti-inflammatory, antioxidant, anticancer, and antimicrobial activities.
CSN19889 Purpurin 81-54-9 Purpurin, a natural product isolated and purified from the herbs of Rubia cordifolia L. with antifungal activity, suppresses C. albicans morphogenesis and causes distorted biofilm formation, and is a specific inhibitor of Adipocyte-derived leucine aminopeptidase and could be developed as an anti-angiogenic agent.
CSN19372 Physcion 521-61-9 Physcion is an anthraquinone isolated and purified from roots of Rheum officinale Baill.
CSN13528 Physcion 8-O-beta-D-Monoglucoside 23451-01-6 Physcion 8-O-beta-d-monoglucoside is a natural product.
CSN13997 Phyllostine 27270-89-9 Phyllostine, a natural product isolated and purified from Pencillium urticae, appears to be their more immediate precursor, since PCMB-treated extracts of J2 converted Phyllostine but not isoepoxydon to these metabolites.
CSN19333 Oxymatrine 16837-52-8 Oxymatrine is a quinolizidine alkaloid extracted from the root of Sophora flavescens, which is used for the treatment of viral hepatitis, cancer, viral myocarditis, gastrointestinal hemorrhage and skin diseases.
CSN13536 Obtusin 70588-05-5 Obtusin is a natural product isolated and purified from Semen Cassiae.
CSN20571 Menaquinone-7 2124-57-4 Menaquinone-7 is a long-chain menaquinone member of Vitamin K2, showing anti-cancer activity.
CSN20565 Menaquinone-4 863-61-6 Menaquinone-4 is the most important member of short-chain menaquinones in Vitamine K2.
CSN19714 Juglone 481-39-0 Juglone significantly inhibits the proliferation and induce the apoptosis of SiHa cells and Caski cells, stimulates suicidal erythrocyte death or eryptosis at least in part by upregulation of ceramide abundance, energy depletion and activation of PKC, and prevents high-fat diet-induced liver injury and nerve inflammation in mice through inhibition of inflammatory cytokine secretion, NF-kappa B activation and endotoxin production. It's a natural product isolated and purified from the barks of Juglans regia L..
CSN15179 Isodiospyrin 20175-84-2 Isodiospyrin, a natural product isolated and purified from the herbs of Diospyros morrisiana, exhibits remarkably good antifungal activity, the MIC values of the isodiospyrin was 5-160 μg/mL & the MFC values was 40-160 μg/mL.
CSN20203 Hypocrellin B 123940-54-5 Hypocrellin B, a natural product isolated and purified from Hypocrella bambusae, has sonodynamic action to induce mitochondrial damage, survival inhibition, apoptosis and inhibit adhesion and migration of cancer cells.
CSN13964 Aurantio-Obtusin 67979-25-3 GlucoAurantio-obtusin, a natural product isolated and purified from the seeds of Cassia obtusifolia L., possesses hypotensive and hypolipidemic effects.
CSN18468 Emodin 518-82-1 Emodin shows antiproliferative effects in cancer cells that are regulated by different signaling pathways, it is a naturally occurring anthraquinone present in the roots and barks of numerous plants.
CSN17013 Dimethylacrylshikonin 24502-79-2 Dimethylacrylshikonin, a natural product isolated and purified from the roots of Lithosperraum erythrorhizon Sieb. et Zucc. with anti-proliferate activity, is a promising agent for developing an improved strategy for radiotherapy against tumors.
CSN16710 Diacerein   13739-02-1 Diacerein is a symptomatic slow-acting medicine in osteoarthritis which can reduce the level of IL-1 receptors leading to fewer receptors to form heterodimer complexes.
CSN21397 Deoxylapachol 3568-90-9 Deoxylapachol induced fungal cell wall stress and inhibited fungal growth.
CSN14072 Dehydro-alpha-Lapachone 15297-92-4 Dehydro-alpha-lapachone, a natural product isolated and purified from the roots of Radermachera sinica with antifungal, antibacterial and antitumor activities, can be as a potential drug for reducing cancer metastasis and can inhibit vessel regeneration, interfere with vessel anastomosis, and limit plexus formation in zebrafish.
CSN14045 Citreorosein 481-73-2 Citreorosein, a cAMP phosphodiesterase inhibitor isolated and purified from the root and rhizome of Rheum palmatum L., has anti-inflammatory effect, inhibits proinflammatory cytokines production through the inhibition of both MAPKs and AKT-mediated IκB kinase (IKK) phosphorylation and subsequent inhibition of transcription factor NF-κB activation.
CSN14045 Citreorosein 481-73-2 Citreorosein, a cAMP phosphodiesterase inhibitor isolated and purified from the root and rhizome of Rheum palmatum L., has anti-inflammatory effect, inhibits proinflammatory cytokines production through the inhibition of both MAPKs and AKT-mediated IκB kinase (IKK) phosphorylation and subsequent inhibition of transcription factor NF-κB activation.
CSN17313 Chrysophanol 481-74-3 Chrysophanol, a natural anthraquinone isolated from Dianella longifolia, is an EGFR/mTOR pathway inhibitor.
CSN14572 Chrysophanol 8-O-Glucoside 13241-28-6 Chrysophanol 8-O-glucoside, a natural product isolated and purified from the roots of Rheum with potent inhibitory effect on collagen- and thrombin-induced platelet aggregation, only inhibits platelet phosphatidylserine exposure, but not exerts direct inhibition on intrinsic factors, suggests that it may be of therapeutic benefit for the prevention of platelet-related cardiovascular diseases.
CSN13535 Chrysoobtusin 70588-06-6 Chrysoobtusin is a natural product isolated and purified from Semen Cassiae.
CSN14573 Averantin 5803-62-3 Averantin, a metabolite of Aspergillus sp. associated with Panax notoginseng, exhibits antifungal activity against Fusariumsolani, pathogenic fungus of P. notoginseng, with minimum inhibitory concentrations (MICs) of 16-32 ug/mL, and shows antibacterial activity against Bacillussubtilis with MICs of 16-32 ug/mL.
CSN14071 alpha-Lapachone 4707-33-9 alpha-Lapachone, a natural product isolated and purified from the barks of Catalpa ovata, does not induce H₂O₂ formmation but shows an approximately the same trypanocidal activity of beta-lapachone.
CSN17350 Aloe-Emodine 481-72-1 Aloe-emodin, a natural product isolated and purified from the root of Rheum palmatum L. with a specific in vitro and in vivo anti-neuroectodermal tumor activity, reduces the toxicity and ROS induced by both monomeric and oligomeric Aβ species, appears to have some protective effect not only against hepatocyte death but also on the inflammatory response subsequent to lipid peroxidation and has a strong non-carcinogenic stimulant-laxative action when applied to the skin, although it may increase the carcinogenicity of some kind of radiation. Aloe-Emodine dose-dependently inhibited cleavage activity of the 3CLpro with IC50 value of 366μM in the cell-based assay.
CSN14762 6-Hydroxyrubiadin 87686-86-0 6-Hydroxyrubiadin is a natural product isolated and purified from the roots of Rubia cordifolia L..
CSN14687 2-Methoxystypandrone 85122-21-0 2-Methoxystypandrone, a natural product isolated and purified from the roots of Polygonum cuspidatum, displays an immunomodulatory effect in a cellular model, specifically inhibits JAK and IKKβ kinase activities, blocks inflammatory responses by impairing NF-κB signaling to limit the inflammation and oxidative stress for preservation of BBB integrity, concomitantly promotes neurodevelopmental protein expression and endogenous neurogenesis through inactivation of GSK3β to enhance β-catenin signaling for upexpression of neuroprotective genes and proteins, and has anti-osteoclastogenic effect, could reflect the block of RANKL-induced association of TRAF6-TAK1 complexes with consequent decrease of IkappaB-mediated NF-kappaB and mitogen-activated protein kinases-mediated c-Fos activation pathways and suppression of NFATc1 and other gene expression, essential for bone resorption.
CSN14925 2-CarbaMoyl-3-Hydroxy-1,4-Naphthoquinone 103646-20-4 2-CarbaMoyl-3-hydroxy-1,4-naphthoquinone is a natural product isolated and purified from plants.
CSN18689 2,6-Dimethoxy-1,4-Benzoquinone 530-55-2 2,6-Dimethoxy-1,4-benzoquinone exhibits strong antibacterial activities against S. pyogenes, S. mitis, and S. mutans with MIC values of 7.8, 7.8, and 15.6 ug/mL, and MBC values of 7.8, 7.8, and 31.2 ug/mL respectively. It also produces genotoxic effects in patients taking dimethophrine, it's a natural product isolated and purified from the barks of Liriodendron tulipifera.
CSN15309 1-O-Methylnataloe-Emodin 103392-51-4 1-O-Methylnataloe-emodin is a natural product isolated and purified from plants.
CSN14201 1-Hydroxy-2-Methylanthraquinone 6268-09-3 1-Hydroxy-2-methylanthraquinone is a natural product isolated and purified from the roots of Rubia cordifolia with promising larvicidal activity.
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