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Essential component of the RMI complex, a complex that plays an important role in the processing of homologous recombination intermediates to limit DNA crossover formation in cells. Promotes TOP3A binding to double Holliday junctions (DHJ) and hence stimulates TOP3A-mediated dissolution. Required for BLM phosphorylation during mitosis. Within the BLM complex, required for BLM and TOP3A stability.

RMI1

货号 产品名 CAS号 信息
CSN29568 PIP-199 622795-76-0 PIP-199 is the most selective inhibitor of the RMI core complex/MM2 interaction.
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