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ROR

ROR

货号 产品名 CAS号 信息
CSN18188 SR-3335 293753-05-6 SR3335 can selectively bind to RORα and competitively inhibit the binding of 25-hydroxycholesterol to the ligand binding domain with Ki of 220 nM.
CSN17703 SR-1001 1335106-03-0 SR1001 is a selective RORα and RORγ inverse agonist and inhibits TH17 cell differentiation and function.
CSN23654 SR 0987 303126-97-8 SR 0987 is an agonist of T cell-specific RORγ (RORγt) with EC50 of 800 nM. It can induce IL-17 expression and decrease PD-1 expression in T cells.
CSN17833 RORgamma-t-IN-1 1426802-50-7 RORγt-IN-1 is a potent, orally bioavailable RORγt inhibitor with pIC50 of 8.4 and > 8.2 for RORγ FRET assay and Th17 assay.
CSN21433 L 601920-0 20231-57-6 L 601920-0 is a ROR gamma modulator extracted from patent US20110263046 A1, in figure 2.
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