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ROS

ROS

货号 产品名 CAS号 信息
CSN27384 Urolithin C 165393-06-6 Urolithin C, a gut-microbial metabolite of Ellagic acid, is a glucose-dependent activator of insulin secretion. Urolithin C is a L-type Ca2+ channel opener and enhances Ca2+ influx. Urolithin C induces cell apoptosis through a mitochondria-mediated pathway and also stimulates reactive oxygen species (ROS) formation.
CSN20526 U-74389G 153190-29-5 U-74389G is an antioxidant which prevents iron-dependent lipid peroxidation. It protects against ischemia-reperfusion injury in animal heart, liver, and kidney models.
CSN13774 Tiopronin 1953-02-2 Tiopronin, derivative of glycine, is used to control the rate of cystine precipitation and excretion. It can be used as an antioxidant agent and radical scavenger.
CSN18690 Tempol 2226-96-2 Tempol is a superoxide scavenger that displays neuroprotective, anti-inflammatory and analgesic effects.
CSN27569 Tempo 2564-83-2 Tempo is a classic nitroxide radical and is a selective scavenger of mitochondrial ROS that dismutases superoxide in the catalytic cycle. Tempo induces DNA-strand breakage. Tempo can be used as an organocatalyst for the oxidation of primary alcohols to aldehydes. Tempo has mutagenic and antioxidant effects.
CSN12258 Scutellarein 529-53-3 Scutellarin is cytotoxic to cancer cells and could induce DNA damage, metabolic suppression and mitochondrial reactive oxygen species. It has has antioxidant, anti-inflammatory, and antiproliferative biological activities that can be can be found in scutellaria lateriflora.
CSN16432 Schisandrin B 61281-37-6 Schisandrin B is a naturally occuring anti-inflammatory and antioxidant agent which can inhibit ROS production in microglia.
CSN33149 HPF 686773-84-2 ROS Probe, a cell-permeable, photo-stable hydroxyphenyl-substituted fluorescein compound.
CSN11731 Piperlongumine 20069-09-4 Piperlongumine, a natural alkaloid from Piper longum L., increases the level of reactive oxygen species (ROS) and selectively kills cancer cells. It is a direct TrxR1 inhibitor with suppressive activity against gastric cancer and an inhibitor of CRM1 and is also an inhibitor of PI3K/Akt/mTOR in human breast cancer cells.
CSN14079 Ophiopogonin D 945619-74-9 Ophiopogonin D, a natural product isolated and purified from Radix Ophiopogon japonicus, protects the heart against doxorubicin-induced autophagic injury by reduction of both ROS generation and the disruption of the mitochondrial membrane damage.
CSN12508 Oleuropein 32619-42-4 Oleuropein is an antioxidant polyphenol isolated from the herb of Olea europaea L..
CSN24072 N-Acetylcysteine amide 38520-57-9 N-Acetylcysteine amide is a cell membranes and blood brain barrier permeant thiol antioxidant and neuroprotective agent, reduces ROS production.
CSN23416 L-SelenoMethionine 3211-76-5 L-SelenoMethionine is a naturally occurring amino acid and it is one of the important organic selenium sources.
CSN11185 Idebenone 58186-27-9 Idebenone, a synthetic analog of coenzyme Q10 (CoQ10), can protect mitochondrial membranes against lipid peroxidation and also used as a neuroprotective agent.
CSN12958 Hexaconazole 79983-71-4 Hexaconazole inhibits ergosterol biosynthesis via inhibition of the cytochrome P450-dependent 14α-demethylation of lanosterol, it is a broad-spectrum triazole fungicide.
CSN21114 H2DCFDA 4091-99-0 H2DCFDA, a cell-permeable fluorogenic probe, is useful to detect reactive oxygen species (ROS) and nitric oxide thus determinate the degree of oxidative stress.
CSN26546 GSK5182 877387-37-6 GSK5182 is a specific inverse agonist for estrogen-related receptor γ.
CSN24748 DMNQ 6956-96-3 DMNQ is a 1,4-naphthoquinone with redox cycling property. It increases the formation of superoxide and hydrogen peroxide in cells.
CSN16599 Crocin 42553-65-1 Crocin, a natural product isolated and purified from the stigma of Crocus sativus L., can relax smooth muscles with a great potential to be a candidate for the treatment of asthma, protect liver and skeletal muscle tissue against exercise-induced oxidative damage by preventing reactive oxygen species (ROS) production, improve toxic effects of DZN via reducing lipid peroxidation and restoring altered contractile and relaxant responses in rat aorta, protect rat gastric mucosa against ethanol-induced injury via anti-inflammatory, anti-oxidative, anti-apoptotic and mucin-secretagogue mechanisms that are probably mediated by enhanced PGE2 release, significantly inhibit the growth of HO-8910 cells and arrest them in the G0/G1 phase, and also promote ovarian cancer HO-8910 cell apoptosis, most likely by increasing p53 and Fas/APO-1 expression, and then activating the apoptotic pathway regulated by Caspase-3.
CSN10376 BAPTA 85233-19-8 BAPTA is an chelator of Ca2+ that can suppress intracellular reactive oxygen species (ROS). BAPTA is used as a neuroprotective agent.
CSN18374 ATN-224 649749-10-0 ATN-224, a copper-chelator agent, can inhibit intracellular SOD1 with IC50 of 17.5 nM.
CSN16436 Acetylcysteine 616-91-1 Acetylcysteine is an inhibitor of ROS and the production of TNF. It is a pharmaceutical drug and nutritional supplement used as mucolytic agent.
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