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RSK

RSK

货号 产品名 CAS号 信息
CSN20281 SL 0101-1 77307-50-7 SL0101 is a selective inhibitor of ribosomal S6 kinase (RSK) (IC50 = 89 nM for RSK2) which does not inhibit upstream kinases such as MEK, Raf and PKC. SL0101 Inhibits the growth of MCF-7 human breast cancer cells with no effect on the normal breast cell line.
CSN15894 PF-4708671 1255517-76-0 PF-4708671 is an inhibitor of S6K1 (p70 ribosomal S6 kinase 1) with Ki and IC50 of 20 nM and 160 nM, respectively.
CSN21078 M2698 1379545-95-5 MSC2363318A, also known as M2698, is an orally available inhibitor of the serine/threonine protein kinases ribosomal protein S6 Kinase (p70S6K) and Akt (protein kinase B), with potential antineoplastic activity.
CSN17452 LY-2584702 tosylate salt 1082949-68-5 LY2584702 tosylate salt is an inhibitor of p70S6K signaling and can prevent the phosphorylation of S6 subunit of ribosomes.
CSN15762 LY-2584702 free base 1082949-67-4 LY2584702 is an orally available inhibitor of p70S6K signaling and inhibits p70S6K and prevents phosphorylation of the S6 subunit of ribosomes.
CSN17451 LY-2584702 hydrochloride 1082948-81-9 LY2584702 HCl is an orally available inhibitor of p70S6K signaling and inhibits p70S6K and prevents phosphorylation of the S6 subunit of ribosomes.
CSN17965 LJI308 1627709-94-7 LJI308 is a potent pan-RSK inhibitor, with IC50 of 6 nM, 4 nM, and 13 nM for RSK1, RSK2, and RSK3, respectively.
CSN17966 LJH685 1627710-50-2 LJH685 is a potent pan-RSK inhibitor with IC50 of 6 nM, 5 nM and 4 nM for RSK1, RSK2, and RSK3, respectively.
CSN15722 FMK 821794-92-7 FMK is an an irreversible RSK2 kinase inhibitor, that covalently modifies the C-terminal kinase domain of RSK.
CSN18447 CMK 821794-90-5 CMK is a RSK2 kinase inhibitor, used for cancer treatment.
CSN26327 BRD7389 376382-11-5 BRD7398 is a RSK kinase inhibitor that induces insulin expression and differentiation of pancreatic alpha into beta cells. It inhibits RSK1, RSK2 and RSK3 with IC50 values of 1.5, 2.4 and 1.2 uM, respectively.
CSN17680 BIX 02565 1311367-27-7 BIX-02565 is a ribosomal S6 kinase 2 (RSK2) inhibitor with an IC50 of 1.1 nM.
CSN12314 BI-D1870 501437-28-1 BI-D1870 is an inhibitor of S6 ribosome which can inhibit RSK1, RSK2, RSK3, RSK4 with IC50 of 31 nM, 24 nM, 18 nM and 15 nM, respectively.
CSN13758 AT13148 1056901-62-2 AT13148 is an oral, ATP-competitive, multi-AGC kinase inhibitor with IC50 of 38 nM/402 nM/50 nM, 8 nM, 3 nM, and 6 nM/4 nM for Akt1/2/3, p70S6K, PKA, and ROCKI/II, respectively.
CSN43417 FMK-MEA 1414811-15-6
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