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RUNX proteins belong to a family of metazoan transcription factors that serve as master regulators of development. They are frequently deregulated in human cancers, indicating a prominent and, at times, paradoxical role in cancer pathogenesis.
| 货号 | 产品名 | CAS号 | 信息 |
|---|---|---|---|
| CSN26341 | N-Acetylmuramyl-L-alanyl-D-isoglnaminehydrate | 53678-77-6 | Muramyl dipeptide, a synthetic immunoreactive peptide, is an inducer of bone formation through induction of Runx2. Muramyl dipeptide directly enhances osteoblast differentiation by up-regulating Runx2 gene expression through MAPK pathways. Muramyl dipeptide indirectly attenuates osteoclast differentiation through a decreased RANKL/OPG ratio. |
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