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sEH is a member of the epoxide hydrolase family. This enzyme, found in both the cytosol and peroxisomes, binds to specific epoxides and converts them to the corresponding diols.

sEH

货号 产品名 CAS号 信息
CSN23555 TPPU 1222780-33-7 TTPU is an inhibitor of epoxide hydrolase (sEH) with IC50 of 3.7 nM with anti-inflammatory and anti-atherosclerotic activities.
CSN25628 PTUPB 1287761-01-6 PTUPB is a novel dual COX2 and sHE (soluble epoxide hydrolase) inhibitor. Treatment with PTUPB reduced body weight, liver weight, liver triglyceride and cholesterol content, and the expression of lipolytic/lipogenic and lipid uptake related genes (Acc, Cd36, and Cidec) in HFD mice. This made it be a promising potential therapy for liver steatosis associated with obesity.
CSN25287 AUDA 479413-70-2 AUDA is a potent soluble epoxide hydrolase (sEH) inhibitor with IC50s of 18 and 69 nM for the mouse and human sEH, respectively and with anti-inflammatory activity.
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