Sesquiterpenoids

Sesquiterpenoids
第页，共 5 页

货号	产品名	CAS号	信息
CSN20351	β-Elemene	515-13-9	β-Elemene is a natural sesquiterpene found in various plants and imparts floral aromas to some plants. This compound has been reported to inhibit the proliferation of a wide range of tumors.
CSN17004	α-Cyperone	473-08-5	α-Cyperone, a natural product isolated and purified from the hizomes of Cyperus rotundus L., is associated with the down-regulation of COX-2,IL-6,Nck-2,Cdc42 and Rac1, resulting in reduction of inflammation.
CSN14948	Pterosin B	34175-96-7	Pterosin B is a natural product isolated and purified from the aerial parts of Pteris semipinnata, is a salt-inducible kinase 3 (Sik3) pathway inhibitor, preventing chondrocyte hypertrophy and osteoarthritis in mice by inhibiting Sik3.
CSN14948	Pterosin B	34175-96-7	Pterosin B is a natural product isolated and purified from the aerial parts of Pteris semipinnata, is a salt-inducible kinase 3 (Sik3) pathway inhibitor, preventing chondrocyte hypertrophy and osteoarthritis in mice by inhibiting Sik3.
CSN18699	Parthenolide	20554-84-1	Parthenolide is a sesquiterpene lactone from the plant feverfew (T. parthenium) with multiple biological functions. Parthenolide inhibits the growth of the promastigote form of L. amazonensis with IC50 of 3.6 μg/mL, induces apoptosis in cancer cells and blocks inflammation by inhibiting signaling through NF-κB.
CSN19880	Nardosinone	23720-80-1	Nardosinone was isolated as an enhancer of nerve growth factor (NGF) from Nardostachys chinensis. Nardosinone (0.1-100 microM) enhanced dibutyryl cyclic AMP (dbcAMP, 0.3 mM)- and staurosporine (10 nM)-induced neurite outgrowth from PC12D cells in a concentration-dependent manner, suggesting that Nardosinone enhances a downstream step of MAP kinase in the MAP kinase-dependent signaling pathway.
CSN19969	Linderane	13476-25-0	Linderane, a natural product isolated and purified from the roots of Lindera aggregata( Sims) Kosterm, is an inactivator of CYP2C9.
CSN14461	Isofuranodiene	57566-47-9	Isofuranodiene, a natural product isolated and purified from the herbs of Chloranthus spicatus, has anticancer activity, by inhibiting the proliferation and inducing apoptosis in cancer cells, protects GalN/LPS-induced liver injury in SD rats, it may be a potential functional food ingredient for the prevention and treatment of liver diseases and can induce apoptosis in colon cancer cells in a time and concentration-dependent manner suggesting a potential role as models for the development of chemopreventive agents.
CSN17221	Isoeugenyl Acetate	5912-87-8	Isoeugenyl acetate is a natural product isolated and purified from Cinnamon bark oil.
CSN16838	Guaiol	489-86-1	Guaiol, a natural product isolated and purified from the roots of Ferula ferulaeoides with insecticidal activity, shows significant inhibition of aphids at a concentration of 70 mg/L and good contact activities against the 4th instar larvae of Mythimna separate and 3rd instar larvae of Plutella xylostella, with LD50 values of 0.07 and 8.9 mg/larva, as well as fumigation activity against the 4th instar larvae of M.
CSN23313	Guaiazulene	489-84-9	Guaiazulene is a derivative of azulene can be used as skin care products ingredients and volatile dye.
CSN16452	Germacrone	6902-91-6	Germacrone, a natural product isolated and purified from the rhizoma of Curcuma wenyujin with anti-tumor activity, can inhibit the proliferation of breast cancer cell lines by inducing cell cycle arrest and apoptosis through mitochondria-mediated caspase pathway, and may be a potent chemopreventive drug candidate for liver cancer via regulating the expression of proteins related to G2/M cell cycle and apoptosis, and p53 and oxidative damage may play important roles in the inhibition of human hepatoma cells growth by germacrone.
CSN16274	Fraxinellone	28808-62-0	Fraxinellone, a natural product isolated and purified from the root barks of Dictamnus dasycarpus Turcz. with neuroprotective, vasorelaxing, insecticidal, and antimicrobial activities, is a selective blocker of voltage-dependent Ca2+ channel, while dictamine relaxed the rat aorta by suppressing the Ca2+ influx through both voltage-dependent and receptor-operated Ca2+ channels, and can dramatically induce apoptosis of activated peripheral CD4(+) T cells in vivo, consequently resulting in less CD4(+) T-cell activation and infiltration to the liver.
CSN13554	Eupalinolide B	877822-41-8	Eupalinolide A is a natural product isolated and purified from the herbs of Eupatorium lindleyanum DC.
CSN13554	Eupalinolide B	877822-41-8	Eupalinolide A is a natural product isolated and purified from the herbs of Eupatorium lindleyanum DC.
CSN23306	Dihydroactinidiolide	17092-92-1	Dihydroactinidiolide is a volatile terpene occurs naturally in plants and animals. It is a component of pheromones in insects and may also shows potent phytotoxin and anticancer activity.
CSN16370	Curcumol	4871-97-0	Curcumol is a sesquiterpene originally isolated from curcuma rhizomes showing anticancer activities both in vitro and in vivo.
CSN16398	Costunolide	553-21-9	Costunolide shows anti-inflammatory and anti-oxidant activities and also induces apoptosis. It is a sesquiterpene lactone isolated from stem bark of Magnolia sieboldii,
CSN16181	Carabrone	1748-81-8	Carabrone, a natural product isolated and purified from the herbs of Carpesium abrotanoides, exhibit antifungal activities in vitro or in vivo.
CSN14698	Brevilin A	16503-32-5	Brevilin A, a natural product isolated and purified from the herbs of Centipeda minima, is a strong impetus for the development of selective JAK-STAT inhibitors and therapeutic drugs in order to improve survival of patients with hyperactivated JAKs and STATs, and has antigiardial activity (IC50 = 16.1 μM) and was similarly active in vitro against Entamoeba histolytica (IC50 between 4.5 and 9 μM) and against Plasmodium falciparum (IC50 = 9.42 μM).
CSN19776	Blumenol C Glucoside	135820-80-3	Blumenol C glucoside is a natural product isolated and purified from the barks of Pseudolarix amabilis.
CSN17638	Atractyloside A	126054-77-1	Atractyloside A is a natural TCM reference compound.
CSN16456	Atractylenolide III	73030-71-4	Atractylenolide III, a natural product isolated and purified from the rhizome of Atractylodes macrocephala Koidz., may have therapeutic potential in treating homocysteine-mediated cognitive impairment and neuronal injury, and is a potential candidate for treatment of human lung carcinoma by inducing the release of cytochrome c, upregulating the expression of bax and translocating apoptosis-inducing factor.
CSN16457	Atractylenolide I	73069-13-3	Atractylenolide I, a natural compound extracted from largehead atractylodes rhizome, induces apoptosis and brings about cytotoxicity of human promyeloleukemic HL-60 cells. It is also a TLR4-antagonizing agent.
CSN18461	Arglabin	84692-91-1	Arglabin is a sesquiterpene gamma-lactone is isolated from Artemisia glabella and an anticancer natural compound.
CSN18518	Alismoxide	87701-68-6	Alismoxide is a natural product isolated and purified from Curcuma comosa.
CSN16394	Alantolactone	546-43-0	Alantolactone is a sesquiterpene lactone with potential activity against triple-negative breast cancer MDA-MB-231 cells by suppressing the signal transducer and activator of transcription 3 (STAT3) signaling pathway.
CSN16854	(RS)-Abscisic Acid	14375-45-2	(RS)-abscisic acid is a natural product act as a negative regulator of plant growth.
CSN16837	(-)-Globulol	489-41-8	(-)-Globulol is a natural product isolated and purified from the fruits of Eucalyptus globulus Labill., showing antimicrobial activity against Xanthomonas vesicatoria and Bacillus subtilis, the IC50 value of 158.0 mg/ mLand 737.2 mg/ mL, respectively.

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