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Sesquiterpenoids

Sesquiterpenoids

货号 产品名 CAS号 信息
CSN20351 β-Elemene 515-13-9 β-Elemene is a natural sesquiterpene found in various plants and imparts floral aromas to some plants. This compound has been reported to inhibit the proliferation of a wide range of tumors.
CSN17004 α-Cyperone 473-08-5 α-Cyperone, a natural product isolated and purified from the hizomes of Cyperus rotundus L., is associated with the down-regulation of COX-2,IL-6,Nck-2,Cdc42 and Rac1, resulting in reduction of inflammation.
CSN14948 Pterosin B 34175-96-7 Pterosin B is a natural product isolated and purified from the aerial parts of Pteris semipinnata, is a salt-inducible kinase 3 (Sik3) pathway inhibitor, preventing chondrocyte hypertrophy and osteoarthritis in mice by inhibiting Sik3.
CSN14948 Pterosin B 34175-96-7 Pterosin B is a natural product isolated and purified from the aerial parts of Pteris semipinnata, is a salt-inducible kinase 3 (Sik3) pathway inhibitor, preventing chondrocyte hypertrophy and osteoarthritis in mice by inhibiting Sik3.
CSN18699 Parthenolide 20554-84-1 Parthenolide is a sesquiterpene lactone from the plant feverfew (T. parthenium) with multiple biological functions. Parthenolide inhibits the growth of the promastigote form of L. amazonensis with IC50 of 3.6 μg/mL, induces apoptosis in cancer cells and blocks inflammation by inhibiting signaling through NF-κB.
CSN19969 Linderane 13476-25-0 Linderane, a natural product isolated and purified from the roots of Lindera aggregata( Sims) Kosterm, is an inactivator of CYP2C9.
CSN14461 Isofuranodiene 57566-47-9 Isofuranodiene, a natural product isolated and purified from the herbs of Chloranthus spicatus, has anticancer activity, by inhibiting the proliferation and inducing apoptosis in cancer cells, protects GalN/LPS-induced liver injury in SD rats, it may be a potential functional food ingredient for the prevention and treatment of liver diseases and can induce apoptosis in colon cancer cells in a time and concentration-dependent manner suggesting a potential role as models for the development of chemopreventive agents.
CSN17221 Isoeugenyl Acetate 5912-87-8 Isoeugenyl acetate is a natural product isolated and purified from Cinnamon bark oil.
CSN16838 Guaiol 489-86-1 Guaiol, a natural product isolated and purified from the roots of Ferula ferulaeoides with insecticidal activity, shows significant inhibition of aphids at a concentration of 70 mg/L and good contact activities against the 4th instar larvae of Mythimna separate and 3rd instar larvae of Plutella xylostella, with LD50 values of 0.07 and 8.9 mg/larva, as well as fumigation activity against the 4th instar larvae of M.
CSN23313 Guaiazulene 489-84-9 Guaiazulene is a derivative of azulene can be used as skin care products ingredients and volatile dye.
CSN16452 Germacrone 6902-91-6 Germacrone, a natural product isolated and purified from the rhizoma of Curcuma wenyujin with anti-tumor activity, can inhibit the proliferation of breast cancer cell lines by inducing cell cycle arrest and apoptosis through mitochondria-mediated caspase pathway, and may be a potent chemopreventive drug candidate for liver cancer via regulating the expression of proteins related to G2/M cell cycle and apoptosis, and p53 and oxidative damage may play important roles in the inhibition of human hepatoma cells growth by germacrone.
CSN16274 Fraxinellone 28808-62-0 Fraxinellone, a natural product isolated and purified from the root barks of Dictamnus dasycarpus Turcz. with neuroprotective, vasorelaxing, insecticidal, and antimicrobial activities, is a selective blocker of voltage-dependent Ca2+ channel, while dictamine relaxed the rat aorta by suppressing the Ca2+ influx through both voltage-dependent and receptor-operated Ca2+ channels, and can dramatically induce apoptosis of activated peripheral CD4(+) T cells in vivo, consequently resulting in less CD4(+) T-cell activation and infiltration to the liver.
CSN13554 Eupalinolide B 877822-41-8 Eupalinolide A is a natural product isolated and purified from the herbs of Eupatorium lindleyanum DC.
CSN13554 Eupalinolide B 877822-41-8 Eupalinolide A is a natural product isolated and purified from the herbs of Eupatorium lindleyanum DC.
CSN23306 Dihydroactinidiolide 17092-92-1 Dihydroactinidiolide is a volatile terpene occurs naturally in plants and animals. It is a component of pheromones in insects and may also shows potent phytotoxin and anticancer activity.
CSN16370 Curcumol 4871-97-0 Curcumol is a sesquiterpene originally isolated from curcuma rhizomes showing anticancer activities both in vitro and in vivo.
CSN16398 Costunolide 553-21-9 Costunolide shows anti-inflammatory and anti-oxidant activities and also induces apoptosis. It is a sesquiterpene lactone isolated from stem bark of Magnolia sieboldii,
CSN16181 Carabrone 1748-81-8 Carabrone, a natural product isolated and purified from the herbs of Carpesium abrotanoides, exhibit antifungal activities in vitro or in vivo.
CSN14698 Brevilin A 16503-32-5 Brevilin A, a natural product isolated and purified from the herbs of Centipeda minima, is a strong impetus for the development of selective JAK-STAT inhibitors and therapeutic drugs in order to improve survival of patients with hyperactivated JAKs and STATs, and has antigiardial activity (IC50 = 16.1 μM) and was similarly active in vitro against Entamoeba histolytica (IC50 between 4.5 and 9 μM) and against Plasmodium falciparum (IC50 = 9.42 μM).
CSN19776 Blumenol C Glucoside 135820-80-3 Blumenol C glucoside is a natural product isolated and purified from the barks of Pseudolarix amabilis.
CSN19302 Bilobalide 33570-04-6 Bilobalide is a biologically active terpenic trilactone present in Ginkgo biloba.
CSN17638 Atractyloside A 126054-77-1 Atractyloside A is a natural TCM reference compound.
CSN16456 Atractylenolide III 73030-71-4 Atractylenolide III, a natural product isolated and purified from the rhizome of Atractylodes macrocephala Koidz., may have therapeutic potential in treating homocysteine-mediated cognitive impairment and neuronal injury, and is a potential candidate for treatment of human lung carcinoma by inducing the release of cytochrome c, upregulating the expression of bax and translocating apoptosis-inducing factor.
CSN16457 Atractylenolide I 73069-13-3 Atractylenolide I, a natural compound extracted from largehead atractylodes rhizome, induces apoptosis and brings about cytotoxicity of human promyeloleukemic HL-60 cells. It is also a TLR4-antagonizing agent.
CSN18461 Arglabin 84692-91-1 Arglabin is a sesquiterpene gamma-lactone is isolated from Artemisia glabella and an anticancer natural compound.
CSN18518 Alismoxide 87701-68-6 Alismoxide is a natural product isolated and purified from Curcuma comosa.
CSN16394 Alantolactone 546-43-0 Alantolactone is a sesquiterpene lactone with potential activity against triple-negative breast cancer MDA-MB-231 cells by suppressing the signal transducer and activator of transcription 3 (STAT3) signaling pathway.
CSN16854 (RS)-Abscisic Acid 14375-45-2 (RS)-abscisic acid is a natural product act as a negative regulator of plant growth.
CSN16837 (-)-Globulol 489-41-8 (-)-Globulol is a natural product isolated and purified from the fruits of Eucalyptus globulus Labill., showing antimicrobial activity against Xanthomonas vesicatoria and Bacillus subtilis, the IC50 value of 158.0 mg/ mLand 737.2 mg/ mL, respectively.
CSN19880 Nardosinone 23720-80-1
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