欢迎来到CSNpharm!产品仅用于科研!

400-920-2911 sales@csnpharm.cn

0

Sirtuin

Sirtuin

货号 产品名 CAS号 信息
CSN25238 UBCS039   358721-70-7 UBCS039 is a specific Sirtuin 6 activator which showed robust activating effects on Sirt6-dependent H3K18ac deacetylation of both full-length histone proteins and complete HeLa nucleosomes.
CSN18940 SRT3025 HCl 2070015-26-6 SRT3025 HCl is an orally available sirtuin modulator.
CSN24314 SRT1720 2HCl 1001645-58-4 SRT1720 2HCl is a selective SIRT1 activator.
CSN12523 Sirtinol 410536-97-9 Sirtinol is a specific SIRT1 and SIRT2 inhibitor with IC50 of 131 μM and 38 μM in cell-free assays, respectively.
CSN28412 SIRT5 inhibitor 1 2166487-21-2 SIRT5 inhibitor 1 is "drug-like" and potent SIRT5 inhibitor with IC50 value of 0.11μM.
CSN19216 SirReal2 709002-46-0 SirReal2 is a potent and selective Sirt2 inhibitor with IC50 of 140 nM.
CSN22311 Sirt2-PROTAC-1 2098487-75-1 PROTAC Sirt2 Degrader-12 is a PROTAC selectively targeting on Sirt2, consist an isotype-selective Sirt2 inhibitor SirReal as a warhead linked to cereblon ligand thalidomide.
CSN25457 OSS_128167 887686-02-4 OSS_128167 is a potent selective sirtuin 6 (SIRT6) inhibitor with IC50s of 89 μM, 1578 μM and 751 μM for SIRT6, SIRT1 and SIRT2, respectively. OSS_128167 has anti-HBV activity that inhibits HBV transcription and replication. OSS_128167 has anti-cancer, anti-inflammation and anti-viral effects.
CSN29498 Nicotinamide riboside 1341-23-7 Nicotinamide riboside increases NAD[+] levels and activates SIRT1 and SIRT3, culminating in enhanced oxidative metabolism and protection against high fat diet-induced metabolic abnormalities.
CSN16796 Nicotinamide 98-92-0 Nicotinamide can act as an inhibitor of sirtuins and it is the active component of NAD and NADP.
CSN15959 Inauhzin 309271-94-1 Inauhzin is a small molecule that effectively reactivates p53 by inhibiting SIRT1 activity, and promotes p53-dependent apoptosis of human cancer cells without causing apparently genotoxic stress (IC50=3 μM, in A549 cell).
CSN18677 Fisetin 528-48-3 Fisetin is an active flavonol that can be used in the synthesis of pharmaceutical with anti-inflammatory and antiproliferative activities.
CSN10146 EX-527 49843-98-3 EX-527 is a potent and selective SIRT1 inhibitor with IC50 of 38 nM, exhibits > 200-fold selectivity against SIRT2 and SIRT3.
CSN16491 AK-7 420831-40-9 AK-7 is a selective and brain-permeable SIRT2 inhibitor and is neuroprotective in Huntington disease mouse models.
CSN13831 AGK2 304896-28-4 AGK2 is a potent, and selective SIRT2 inhibitor with IC50 of 3.5 μM that minimally affects either SIRT1 or SIRT3 at 10-fold higher levels.
CSN20654 3-TYP 120241-79-4 3-TYP is a selective inhibitor of SIRT3.
<< PREV 1 NEXT >>
联系
我们