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Smo

Smo

货号 产品名 CAS号 信息
CSN16966 SAG 912545-86-9 SAG is a potent Smo receptor agonist, and activates the Hedgehog signaling pathway, with Kd of 59 nM.
CSN15983 Purmorphamine 483367-10-8 Purmorphamine is an activator of Smoothened, and blocks BODIPY-cyclopamine binding to Smo with IC50 of appr 1.5 μM and also is an inducer of osteoblast differentiation with EC50 of 1 μM.
CSN15911 PF-5274857 1373615-35-0 PF-5274857 is a potent and selective Smoothened (Smo) antagonist, inhibits Hedgehog (Hh) signaling with IC50 and Ki of 5.8 nM and 4.6 nM, respectively, and can penetrate the blood–brain barrier.
CSN15980 Jervine 469-59-0 Jervine is hedgehog signaling inhibitor with IC50 of 500 nM-700 nM that disrupts the interaction with smoothened.
CSN22854 IHR 1 548779-60-8 IHR 1 is a potent Smo antagonist with IC50 of 7.6 nM.
CSN10720 Cyclopamine   4449-51-8 Cyclopamine is a specific Hedgehog (Hh) signaling pathway antagonist of Smoothened (Smo) with IC50 of 46 nM in TM3Hh12 cells.
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