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| 货号 | 产品名 | CAS号 | 信息 |
|---|---|---|---|
| CSN18688 | SKI II | 312636-16-1 | SKI II is an inhibitor of non ATP-competitive sphingosine kinase (SphK) with IC50 of 0.5 μM. |
| CSN23038 | PF 543 HCl | 1706522-79-3 | PF-543 HCl is a cell-permeant inhibitor of SphK1 with a Ki of 3.6 nM, PF-543 is sphingosine-competitive and is more than 100-fold selective for SphK1 over the SphK2 isoform. |
| CSN17876 | K145 HCl | 1449240-68-9 | K145 HCl is a selective SphK2 inhibitor with an IC50 of 4.30±0.06 μM , while no inhibition of SphK1 at concentrations up to 10 μM. |
| CSN24154 | Defensamide | 1104874-94-3 | Defensamide is an activator of SPHK1, and significantly stimulates CAMP mRNA and protein production in KC. |
| CSN16869 | ABC294640 | 915385-81-8 | ABC294640 markedly alters the ratio of ceramide/S1P consistent with inhibition of SK activity in MDA-MB-231 cells. |