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Src

Src

货号 产品名 CAS号 信息
CSN16229 WH-4-023 837422-57-8 WH-4-023 is an inhibitor of Lck and Src with IC50 of 2 nM, 6 nM, respectively.
CSN18218 SU6656 330161-87-0 SU 6656 is an inhibitor of Src kinases and can target Src, Yes, Lyn, and Fyn with IC50 of 280 nM, 20 nM, 130 nM, 170 nM, respectively.
CSN17355 Src Inhibitor 1 179248-59-0 Src inhibitor 1 is an inhibitor of Src and Lck with IC50 of 44 nM and 88nM.
CSN23720 RK 24466 213743-31-8 RK-24466 is an inhibitor of Lck (64-509) and LckCD isoforms with IC50s of <2 nM.
CSN11759 PP2 172889-27-9 PP2 is a ATP-competitive inhibitor of the Src family of protein tyrosine kinases. The IC50s for p56lck, p59fynT, Hck, Src are 4 nM, 5 nM, 5 nM, 100 nM, respectively.
CSN11758 PP1 172889-26-8 PP1 is a selective inhibitor of Src and Lck/Fyn with IC50 of 5 nM, 6 nM, respectively.
CSN12857 PD173955 260415-63-2 PD173955 is an src family-selective tyrosine kinase inhibitor with IC50 of ~22 nM for Src, Yes and Abl kinase and is less potent for FGFRα and no activity on InsR and PKC.
CSN23025 PD 166285 2HCl 212391-63-4 PD 166285 inhibited Src nonreceptor tyrosine kinase, fibroblast growth factor receptor-1, epidermal growth factor receptor and platelet-derived growth factor receptor beta subunit (PDGFR-beta), tyrosine kinases with half-maximal inhibitory potencies (IC50 values) of 8.4 +/- 2.3 nM (n = 6), 39.3 +/- 2.8 nM (n = 16), 87.5 +/- 13.7 nM (n = 6) and 98.3 +/- 7.9 nM (n = 16), respectively.
CSN17507 MCB-613 1162656-22-5 MCB-613 is a stimulator of steroid receptor coactivator (SRC).
CSN18620 Lck Inhibitor 2 944795-06-6 Lck inhibitor 2 is a bis-anilinopyrimidine inhibitor of tyrosine kinases including LCK, BTK, LYN, SYK, and TXK. The IC50 values are 13nM, 9nM, 3nM, 26nM and 2nM for Lck, Btk, Lyn, Btk and Txk respectively.
CSN19857 KB SRC 4 1380088-03-8 KB SRC 4 is a potent and selective c-Src inhibitor (Ki = 44 nM) and does not inhibit c-Abl at concentrations up to 125 μM.
CSN11935 Bosutinib 380843-75-4 Bosutinib is an inhibitor of Src and Abl with IC50 of 1.2 nM and 1 nM.
CSN18293 AZM475271 476159-98-5 AZM475271 is a potent and selective Src kinase inhibitor with IC50 of 5 nM showing no inhibitory activity on Flt3, KDR, Tie-2.
CSN18508 A-770041 869748-10-7 A-770041 is selective and orally active Src-family Lck inhibitor and is a 147 nM inhibitor of Lck(1 mM ATP) and is 300-fold selective against Fyn, the other Src family kinase involved in T-cell signaling.
CSN21118 7-Hydroxy-4-chromone 59887-89-7 7-Hydroxychromone is a Src kinase inhibitor with an IC50 of <300 μM.
CSN13856 1-Naphthyl PP1 221243-82-9 1-Naphthyl PP1 is a selective inhibitor of src family kinases v-Src and c-Fyn as well as the tyrosine kinase c-Abl (IC50 values are 1.0, 0.6, 0.6, 18 and 22 μM for v-Src, c-Fyn, c-Abl, CDK2 and CAMK II respectively).
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