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| 货号 | 产品名 | CAS号 | 信息 |
|---|---|---|---|
| CSN14080 | Pseudoprotodioscin | 102115-79-7 | Pseudoprotodioscin shows a weaker suppressing effect on the production of inflammatory cytokines and can suppress melanogenesis in B16F1 cells. It's a natural product isolated and purified from the rhizomes of Dioscorea nipponica Makino. with moderate cytotoxicity.Pseudoprotodioscin inhibits SREBP1/2 and microRNA 33a/b levels and reduces the gene expression regarding the synthesis of cholesterol and triglycerides. |
| CSN16616 | Praeruptorin B | 73069-28-0 | Praeruptorin D, a natural product isolated and purified from the roots of Peucedanum praeruptorum Dunn., can significantly inhibit the infiltration of activated polymorphonuclear leukocytes (PMNs) and decrease the levels of TNF-α and IL-6 in bronchoalveolar lavage fluid at the same dose, suppresses LPS induced Nuclear Factor-kappa B (NF-κB) pathway activation in the lung by decreasing the cytoplasmic loss of inhibitor κB-α (IκB-α) protein and inhibiting the translocation of p65 from cytoplasm to nucleus. |
| CSN38450 | PF429242 dihydrochloride | 2248666-66-0 | PF429242 2HCl is a reversible and competitive SREBP site 1 protease (S1P) inhibitor with IC50 value of 175nM. |
| CSN13748 | Fatostatin hydrobromide | 298197-04-3 | Fatostatin ia an inhibitor of sterol regulatory element binding protein (SREBP). It impairs the activation of SREBP-1 and SREBP-2. |
| CSN19276 | Fatostatin | 125256-00-0 | Fatostatin A is an inhibitor of SREBP that directly binds SCAP and blocks its ER-to-Golgi transport with IC50 of 2.5 and 10 μM in mammalian cells. |
| CSN50454 | PF 429242 | 947303-87-9 | |
| CSN76150 | 4'-Hydroxyflavanone | 6515-37-3 |
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