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SRPK

SRPK

货号 产品名 CAS号 信息
CSN19078 WNK463 2012607-27-9 WNK463 is a potant With-No-Lysine (WNK) kinase inhibitor with IC50s of 5/1/6/9 nM for WNK1/2/3/4.
CSN23723 WNK-IN-11 2123489-30-3 WNK-IN-11 is a potent, selective and orally active inhibitor of WNK1 kinase with IC50 of 6 nM.
CSN23673 SPHINX31 1818389-84-2 SPHINX31 is a potent and selective inhibitor of serine/arginine-rich protein kinase 1 (SRPK1), with an IC50 of 5.9 nM. SPHINX31 inhibits phosphorylation of serine/arginine-rich splicing factor 1 (SRSF1). SPHINX31 is a potential topical therapeutic for neovascular eye disease[1].
CSN17802 ML281 1404437-62-2 ML281 is a potent and selective serine/threonine kinase (STK33) inhibitor with IC50 of 14 nM. STK33 downregulation is toxic to KRAS-dependent cancer cell lines.
CSN17687 MK2-IN-1 HCl 1314118-94-9 MK2-IN-1 HCl is a non-ATP competitive inhibitor of MAPKAPK2 (MK2) with IC50 of 0.11 μM.
CSN27205 ILK-IN-3 6975-75-3 ILK-IN-3 is an integrin linked kinase inhibitor.
CSN18951 ILK-IN-2 2070015-22-2 ILK-IN-2 is a ILK inhibitor.
CSN24084 GSK8612 2361659-62-1 GSK8612 is a potent and highly selective Tank-binding Kinase-1 (TBK1) inhibitor with pIC50 of 6.8 for recombinant TBK1.
CSN12528 4μ8C 14003-96-4 4μ8C is a potent and selective IRE1 Rnase inhibitor with IC50 of 76 nM.
CSN24165 GSK8612 2361659-62-1
CSN24738 ZT-12-037-01 2328073-61-4
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