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Steroids
| 货号 | 产品名 | CAS号 | 信息 |
|---|---|---|---|
| CSN17211 | α-Estradiol | 57-91-0 | α-Estradiol is an endogenous estrogen receptor ligand (Ki values are 0.2 and 1.2 nM for ERα and ERβ receptors respectively). |
| CSN19989 | Timosaponin BII | 136656-07-0 | Timosaponin BII, a natural product isolated and purified from the rhizomes of Anemarrhena asphodeloides Bunge with antioxidant and anti-dementia activities, can inhibit the up-regulation of BACE1 and reduced the over-production of β-CTF and Aβ in rat retina, which was induced by FeCl3, and may be useful for the treatment of type 2 diabetes. |
| CSN16895 | Tigogenin | 77-60-1 | Tigogenin, a natural product isolated and purified from the herbs of Agave sisalana Perrine, induces apoptosis, associated with overexpression of COX-2 correlated with overproduction of endogenous PGE2, and may modulate differentiation of BMSCs to cause a lineage shift away from the adipocytes and toward the osteoblasts, which is at least mediated by inhibition of PPARgamma and via p38 MAPK pathway. |
| CSN16105 | Sarsasapogenin | 126-19-2 | Sarsasapogenin, a natural product isolated and purified from the rhizomes of Anemarrhena asphodeloides Bunge with anti-inflammatory, anti-diabetes,antidepressant, antitumor and protective effects, against glutamate-induced neurotoxicity in the cultured cortical neurons in rats, can improve memory by elevating the low muscarinic acetylcholine receptor density in brains of memory-deficit rat models, and effectively promote the proliferation, differentiation and mineralization of osteoblasts cultured in vitro, also inhibit the generation of osteoclasts from marrow cells. |
| CSN16105 | Sarsasapogenin | 126-19-2 | Sarsasapogenin, a natural product isolated and purified from the rhizomes of Anemarrhena asphodeloides Bunge with anti-inflammatory, anti-diabetes,antidepressant, antitumor and protective effects, against glutamate-induced neurotoxicity in the cultured cortical neurons in rats, can improve memory by elevating the low muscarinic acetylcholine receptor density in brains of memory-deficit rat models, and effectively promote the proliferation, differentiation and mineralization of osteoblasts cultured in vitro, also inhibit the generation of osteoclasts from marrow cells. |
| CSN19433 | Resibufogenin | 465-39-4 | Resibufogenin, a natural product isolated and purified from the glandular body of Bufo bufo gargarizans Cantor, displays great potential as a chemotherapeutic agent in oncology. |
| CSN20178 | Mogroside IIIE | 88901-37-5 | Mogroside IIIE a naturally occuring cucurbitane glycoside which can attenuate gestational diabetes mellitus through activating of AMPK signaling pathway in mice. |
| CSN19957 | Liriope Muscari Baily Saponins C | 87480-46-4 | Liriope muscari baily saponins C, a natural product isolated and purified from the roots of Liriope muscari, has an anti-thrombotic activity due to down-regulation of the increased mRNA expression levels of IL-6 and TF. |
| CSN19485 | Dioscin | 19057-60-4 | Dioscin, a natural product isolated and purified from the rhizome of Dioscorea Zingiberensis C.H.Wright, is a potent ITGA5 inhibitor, showing potent anti-cancer effect against a variety of tumor cell lines. |
| CSN19954 | Cyasterone | 17086-76-9 | Cyasterone is an inhibitor of EGFR that maybe a promising anti-cancer agent espcially in skin carcinoma. |
| CSN19995 | Chonglou Saponin VII | 68124-04-9 | Chonglou saponin VII, a natural product isolated and purified from the roots of Paris polyphylla, shows inhibitory effects on cell proliferation. |
| CSN19035 | Chenodeoxycholic Acid | 474-25-9 | Chenodeoxycholic acid is a naturally occurring human bile acid, and inhibits production of cholesterol in the liver and absorption in the intestines. |
| CSN19435 | Bufalin | 465-21-4 | Bufalin a major digoxin-like immunoreactive component of the Chinese medicine Chan Su and has been shown to exert a potential for anticancer activity against various human cancer cell lines in vitro. |
| CSN18282 | Arenobufagin | 464-74-4 | Arenobufagin is a natural bufadienolide from toad venom and has potent antineoplastic activity against HCC HepG2 cells as well as corresponding multidrug-resistant HepG2/ADM cells. |
| CSN19445 | 20-Hydroxyecdysone | 5289-74-7 | 20-Hydroxyecdysone is a naturally occurring ecdysteroid hormone which controls the ecdysis (moulting) and metamorphosis of arthropods. |
