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Steroids
| 货号 | 产品名 | CAS号 | 信息 |
|---|---|---|---|
| CSN19989 | Timosaponin BII | 136656-07-0 | Timosaponin BII, a natural product isolated and purified from the rhizomes of Anemarrhena asphodeloides Bunge with antioxidant and anti-dementia activities, can inhibit the up-regulation of BACE1 and reduced the over-production of β-CTF and Aβ in rat retina, which was induced by FeCl3, and may be useful for the treatment of type 2 diabetes. |
| CSN16895 | Tigogenin | 77-60-1 | Tigogenin, a natural product isolated and purified from the herbs of Agave sisalana Perrine, induces apoptosis, associated with overexpression of COX-2 correlated with overproduction of endogenous PGE2, and may modulate differentiation of BMSCs to cause a lineage shift away from the adipocytes and toward the osteoblasts, which is at least mediated by inhibition of PPARgamma and via p38 MAPK pathway. |
| CSN19882 | Liriopesides B | 87425-34-1 | Spicatoside B is a natural product isolated and purified from Mentha spicata L. |
| CSN19963 | Ruscogenin | 472-11-7 | Ruscogenin, a natural product isolated and purified from the root of Ophiopogon japonicus with significant anti-inflammatory and anti-thrombotic activities, significantly attenuates LPS-induced acute lung injury (ALI )via inhibiting expressions of TF and iNOS and NF-κB p65 activation, protects the brain against ischemic damage caused by middle cerebral artery occlusion (MCAO) which may be through downregulation of NF-κB-mediated inflammatory responses, inhibits activation of neutrophil through cPLA 2 , PAK, Akt, MAPKs, cAMP, and PKA signaling pathways, and may attenuate high-fat diet (HFD)-induced steatohepatitis through downregulation of NF- κB-mediated inflammatory responses, reducing hepatic lipogenic gene expression, and upregulating proteins in β-oxidation pathway. |
| CSN18003 | Pseudobufarenogin | 17008-69-4 | Pseudobufarenogin is a natural compound extracted from toad species with unknown details. |
| CSN19915 | Prosapogenin A | 19057-67-1 | Prosapogenin A, a natural product isolated and purified from the roots of Ophiopogon japonicus with anti-obesity and immunomodulating effect, exhibits cytotoxic activity against the cancer cell line K562 in vitro. |
| CSN19990 | Polyphyllin VI | 55916-51-3 | Polyphyllin VI, a natural product isolated and purified from the rhizomes of Paris yunnanensis Franch. with hemostasis, expectorant, bacteriostasis, anticytotoxic, anti-pregnancy and sperm-killing effects. |
| CSN19985 | Polyphyllin II | 76296-72-5 | Polyphyllin II is a natural product isolated and purified from the rhizomes of Paris yunnanensis Franch. with hemostasis, expectorant, bacteriostasis, anticytotoxic, anti-pregnancy and sperm-killing effects. |
| CSN19957 | Liriope muscari baily saponins C | 87480-46-4 | Liriope muscari baily saponins C, a natural product isolated and purified from the roots of Liriope muscari, has an anti-thrombotic activity due to down-regulation of the increased mRNA expression levels of IL-6 and TF. |
| CSN19362 | Hecogenin | 467-55-0 | Hecogenin is a natural product isolated and purified from the roots of Aconitum carmichaeli Debx with antioxidant and anti-inflammatory properties, which can protect gastro by K⁺(ATP) channels opening and the COX-2/PG pathway. |
| CSN16894 | Gitogenin | 511-96-6 | Gitogenin, a natural product isolated and purified from the herbs of Agave americana, is a selective inhibitor of UGT1A4, and does not inhibit the activities of major human CYP isoforms. Gitogenin is also an inhibitor of enzyme α-glucosidase with IC50 values of 37.2±0.18 and 33.5±0.22 uM, respectively, and shows moderate stimulation of release activity on growth hormone from rat pituitary cells. |
| CSN19436 | Gamabufotalin | 465-11-2 | Gamabufotalin, a major bufadienolide of Chansu, has been used for cancer therapy due to its desirable metabolic stability and less adverse effect. |
| CSN18260 | Desacetylcinobufagin | 4026-95-3 | Desacetylcinobufagin is a natural compound used for microbial transformation. |
| CSN19995 | Paris saponin VII | 68124-04-9 | Chonglou saponin VII, a natural product isolated and purified from the roots of Paris polyphylla, shows inhibitory effects on cell proliferation. |
| CSN19435 | Bufalin | 465-21-4 | Bufalin a major digoxin-like immunoreactive component of the Chinese medicine Chan Su and has been shown to exert a potential for anticancer activity against various human cancer cell lines in vitro. |
| CSN14485 | Adynerin | 35109-93-4 | Adynerin is a natural product isolated and purified from the herbs of Nerium oleander. |
