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Steroids

Steroids

货号 产品名 CAS号 信息
CSN17211 α-Estradiol 57-91-0 α-Estradiol is an endogenous estrogen receptor ligand (Ki values are 0.2 and 1.2 nM for ERα and ERβ receptors respectively).
CSN19989 Timosaponin BII 136656-07-0 Timosaponin BII, a natural product isolated and purified from the rhizomes of Anemarrhena asphodeloides Bunge with antioxidant and anti-dementia activities, can inhibit the up-regulation of BACE1 and reduced the over-production of β-CTF and Aβ in rat retina, which was induced by FeCl3, and may be useful for the treatment of type 2 diabetes.
CSN16895 Tigogenin 77-60-1 Tigogenin, a natural product isolated and purified from the herbs of Agave sisalana Perrine, induces apoptosis, associated with overexpression of COX-2 correlated with overproduction of endogenous PGE2, and may modulate differentiation of BMSCs to cause a lineage shift away from the adipocytes and toward the osteoblasts, which is at least mediated by inhibition of PPARgamma and via p38 MAPK pathway.
CSN16105 Sarsasapogenin 126-19-2 Sarsasapogenin, a natural product isolated and purified from the rhizomes of Anemarrhena asphodeloides Bunge with anti-inflammatory, anti-diabetes,antidepressant, antitumor and protective effects, against glutamate-induced neurotoxicity in the cultured cortical neurons in rats, can improve memory by elevating the low muscarinic acetylcholine receptor density in brains of memory-deficit rat models, and effectively promote the proliferation, differentiation and mineralization of osteoblasts cultured in vitro, also inhibit the generation of osteoclasts from marrow cells.
CSN16105 Sarsasapogenin 126-19-2 Sarsasapogenin, a natural product isolated and purified from the rhizomes of Anemarrhena asphodeloides Bunge with anti-inflammatory, anti-diabetes,antidepressant, antitumor and protective effects, against glutamate-induced neurotoxicity in the cultured cortical neurons in rats, can improve memory by elevating the low muscarinic acetylcholine receptor density in brains of memory-deficit rat models, and effectively promote the proliferation, differentiation and mineralization of osteoblasts cultured in vitro, also inhibit the generation of osteoclasts from marrow cells.
CSN19433 Resibufogenin 465-39-4 Resibufogenin, a natural product isolated and purified from the glandular body of Bufo bufo gargarizans Cantor, displays great potential as a chemotherapeutic agent in oncology.
CSN20178 Mogroside IIIE 88901-37-5 Mogroside IIIE a naturally occuring cucurbitane glycoside which can attenuate gestational diabetes mellitus through activating of AMPK signaling pathway in mice.
CSN19957 Liriope Muscari Baily Saponins C 87480-46-4 Liriope muscari baily saponins C, a natural product isolated and purified from the roots of Liriope muscari, has an anti-thrombotic activity due to down-regulation of the increased mRNA expression levels of IL-6 and TF.
CSN19485 Dioscin 19057-60-4 Dioscin, a natural product isolated and purified from the rhizome of Dioscorea Zingiberensis C.H.Wright, is a potent ITGA5 inhibitor, showing potent anti-cancer effect against a variety of tumor cell lines.
CSN19954 Cyasterone 17086-76-9 Cyasterone is an inhibitor of EGFR that maybe a promising anti-cancer agent espcially in skin carcinoma.
CSN19995 Chonglou Saponin VII 68124-04-9 Chonglou saponin VII, a natural product isolated and purified from the roots of Paris polyphylla, shows inhibitory effects on cell proliferation.
CSN19035 Chenodeoxycholic Acid 474-25-9 Chenodeoxycholic acid is a naturally occurring human bile acid, and inhibits production of cholesterol in the liver and absorption in the intestines.
CSN19435 Bufalin 465-21-4 Bufalin a major digoxin-like immunoreactive component of the Chinese medicine Chan Su and has been shown to exert a potential for anticancer activity against various human cancer cell lines in vitro.
CSN18282 Arenobufagin 464-74-4 Arenobufagin is a natural bufadienolide from toad venom and has potent antineoplastic activity against HCC HepG2 cells as well as corresponding multidrug-resistant HepG2/ADM cells.
CSN19445 20-Hydroxyecdysone 5289-74-7 20-Hydroxyecdysone is a naturally occurring ecdysteroid hormone which controls the ecdysis (moulting) and metamorphosis of arthropods.
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