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STING
| 货号 | 产品名 | CAS号 | 信息 |
|---|---|---|---|
| CSN19006 | ML RR-S2 CDA Ammonium | 1638750-96-5 | ML RR-S2 CDA ammonium is an inducer of STING (stimulator of interferon genes). ML RR-S2 CDA has enhanced binding affinity to STING and activate all known human STING alleles. |
| CSN29564 | DUN99845 | 727699-84-5 | DUN99845 was reported as a STING inhbiitor, which inhibited the activation of the STING signal pathway and to prevent or treat a STING-mediated disease. |
| CSN18324 | c-Di-AMP | 54447-84-6 | Cyclic-di-AMP is a second messenger molecule produced in bacteria but not in mammals and can induce a strong immune response in vitro and in vivo. |
| CSN27873 | ChX710 | 2438721-44-7 | ChX710 can boost cellular response to cytosolic DNA via STING. It efficiently primed cellular response to transfected plasmid DNA as assessed by potent synergistic effects on IFN-β secretion and ISG expression levels. |
| CSN18467 | cGAMP | 849214-04-6 | cGAMP, an endogenous second messenger, can induce the formation of cytokines and promote innate immune response. It also acts as an activator of STING with antitumor activity. |
| CSN22894 | CCCP | 555-60-2 | CCCP can inhibit the activation of STING and is widely used as a protonophore uncoupling agent for oxidative phosphorylation. |
| CSN23535 | C-178 | 329198-87-0 | C-178 is a STING inhibitor that can block palmitoylation (PMA)-induced clustering of STING. |
| CSN22907 | C-176 | 314054-00-7 | C-176 is a STING inhibitor with anti-inflammatory effection. |
| CSN23676 | H-151 | 941987-60-6 | 1-(4-Ethylphenyl)-3-(1H-indol-3-yl)urea, also known as H-151, is a irreversible inhibitor of STING that can inhibit the type I interferon (IFN) response and reduce the phosphorylation of TBK1 and palmitoylation of human STING in vitro. |
| CSN34985 | STING agonist-4 | 2138300-40-8 |
