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STING

STING

货号 产品名 CAS号 信息
CSN23755 STING ligand-1 2365039-41-2 STING ligand-1 is a lead STING ligand with IC50 of 68 nM for HAQ STING.
CSN24506 STING agonist-3 2138299-29-1 STING agonist-3 is a selective small-molecule STING agonist which has durable anti-tumor effect and tremendous potential to improve treatment of cancer.
CSN18399 STING agonist-1 702662-50-8 STING agonist-1 is a human-specific STING agonist that elicits antiviral activity against emerging Alphaviruses.
CSN27270 SR-717   2375421-09-1 SR-717 is a non-nucleotide STING agonist with EC50s of 2.1 μM and 2.2 μM in ISG-THP1 (WT) and ISG-THP1 cGAS KO (cGAS KO) cell lines, respectively. Antitumor activity .
CSN29565 SN-011   2249435-90-1 SN-011 is a STING inhibitor, which inhibited the activation of the STING signal pathway and to prevent or treat a STING-​mediated disease. SN-011 is a demethyl analogue of DUN99845.
CSN16863 ADU-S100 1638241-89-0 ML RR-S2 CDA is a highly active cyclic-di-nucleotide immune stimulators that activate DCs via the cytoplamtic receptor STING (Stimulator of Interferon Genes).
CSN19006 ADU-S100 ammonium salt 1638750-96-5 ML RR-S2 CDA ammonium is an inducer of STING (stimulator of interferon genes). ML RR-S2 CDA has enhanced binding affinity to STING and activate all known human STING alleles.
CSN29564 SN-001   727699-84-5 DUN99845 was reported as a STING inhbiitor, which inhibited the activation of the STING signal pathway and to prevent or treat a STING-​mediated disease.
CSN23276 diABZI STING agonist-1 (Tautomerism) 2138498-18-5 diABZI STING agonist-1 is a selective stimulator of interferon genes (STING) receptor agonist, with EC50s of 130, 186 nM for human and mouse, respectively.
CSN18324 c-di-AMP 54447-84-6 Cyclic-di-AMP is a second messenger molecule produced in bacteria but not in mammals and can induce a strong immune response in vitro and in vivo.
CSN27873 ChX710   2438721-44-7 ChX710 can boost cellular response to cytosolic DNA via STING. It efficiently primed cellular response to transfected plasmid DNA as assessed by potent synergistic effects on IFN-β secretion and ISG expression levels.
CSN18467 cGAMP 849214-04-6 cGAMP, an endogenous second messenger, can induce the formation of cytokines and promote innate immune response. It also acts as an activator of STING with antitumor activity.
CSN22894 CCCP 555-60-2 CCCP can inhibit the activation of STING and is widely used as a protonophore uncoupling agent for oxidative phosphorylation. CCCP is the most commonly used inducer of mitophagy in mammalian cells and is thought to exert its effects by reducing the mitochondrial membrane potential.
CSN23535 C-178 329198-87-0 C-178 is a STING inhibitor that can block palmitoylation (PMA)-induced clustering of STING.
CSN22907 C-176 314054-00-7 C-176 is a STING inhibitor with anti-inflammatory effection.
CSN26922 2',3'-cGAMP 1441190-66-4 2',3'-cGAMP (2'-3'-cyclic GMP-AMP) is a endogenous cGAMP in mammalian cells. 2',3'-cGAMP binds to STING with a high affinity and is a potent inducer of interferon-β (IFNβ). 2',3'-cGAMP is produced in mammalian cells in response to DNA in the cytoplasm[1].
CSN23676 H-151 941987-60-6 1-(4-Ethylphenyl)-3-(1H-indol-3-yl)urea, also known as H-151, is a irreversible inhibitor of STING that can inhibit the type I interferon (IFN) response and reduce the phosphorylation of TBK1 and palmitoylation of human STING in vitro.
CSN38578 cGAMP disodium 2407516-83-8
CSN34985 STING agonist-4 2138300-40-8
CSN42704 diABZI STING agonist-1 2138299-33-7
CSN43448 CL656 1951464-79-1
CSN60003 SR-717 free acid 2375420-34-9
CSN50645 STING agonist-4 TFA 2138300-41-9
CSN50642 STING agonist-20 2591300-72-8
CSN50644 (S)-2-(1-Ethyl-3-methyl-1H-pyrazole-5-carboxamido)-1-(2-hydroxy-2-phenylethyl)-1H-benzo[d]imidazole-5-carboxamide 2248444-14-4
CSN50646 E7766 diammonium salt 2242635-03-4
CSN50643 Oxoacridinylacetic acid derivatived STING agonist 2332803-59-3
CSN50641 diABZI STING agonist 4 2591300-74-0
CSN50648 BNBC 55171-63-6
CSN50647 N-(Methylcarbamoyl)-2-phenyl-2-((5-(p-tolyl)-1,3,4-oxadiazol-2-yl)thio)acetamide 875863-22-2
CSN62640 STING-IN-2 346691-38-1
CSN67865 STING-IN-3 2244881-69-2
CSN74760 4-Methyl-1-((2-(piperidin-1-yl)thiazol-4-yl)methyl)-N-(4-(pyridin-3-yl)phenyl)-1H-pyrrole-2-carboxamide 2247732-89-2
CSN85029 STING agonist-12 2259624-71-8
CSN85113 STING agonist-10 2259308-69-3
CSN85217 STING agonist-11 2259308-68-2
CSN86641 STING agonist-16 652142-94-4
CSN91562 BSP16 2727249-47-8
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