|CSN18399||STING Agonist-1||702662-50-8||STING agonist-1 is a human-specific STING agonist that elicits antiviral activity against emerging Alphaviruses.|
|CSN27270||SR-717||2375421-09-1||SR-717 is a non-nucleotide STING agonist with EC50s of 2.1 μM and 2.2 μM in ISG-THP1 (WT) and ISG-THP1 cGAS KO (cGAS KO) cell lines, respectively. Antitumor activity .|
|CSN18467||cGAMP||849214-04-6||cGAMP, an endogenous second messenger, can induce the formation of cytokines and promote innate immune response. It also acts as an activator of STING with antitumor activity.|
|CSN22894||CCCP||555-60-2||CCCP can inhibit the activation of STING and is widely used as a protonophore uncoupling agent for oxidative phosphorylation.|
|CSN23535||C-178||329198-87-0||C-178 is a STING inhibitor that can block palmitoylation (PMA)-induced clustering of STING.|
|CSN22907||C-176||314054-00-7||C-176 is a STING inhibitor with anti-inflammatory effection.|
|CSN23676||H-151||941987-60-6||1-(4-Ethylphenyl)-3-(1H-indol-3-yl)urea, also known as H-151, is a irreversible inhibitor of STING that can inhibit the type I interferon (IFN) response and reduce the phosphorylation of TBK1 and palmitoylation of human STING in vitro.