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STING
货号 | 产品名 | CAS号 | 信息 |
---|---|---|---|
CSN18399 | STING Agonist-1 | 702662-50-8 | STING agonist-1 is a human-specific STING agonist that elicits antiviral activity against emerging Alphaviruses. |
CSN27270 | SR-717 | 2375421-09-1 | SR-717 is a non-nucleotide STING agonist with EC50s of 2.1 μM and 2.2 μM in ISG-THP1 (WT) and ISG-THP1 cGAS KO (cGAS KO) cell lines, respectively. Antitumor activity . |
CSN18467 | cGAMP | 849214-04-6 | cGAMP, an endogenous second messenger, can induce the formation of cytokines and promote innate immune response. It also acts as an activator of STING with antitumor activity. |
CSN22894 | CCCP | 555-60-2 | CCCP can inhibit the activation of STING and is widely used as a protonophore uncoupling agent for oxidative phosphorylation. |
CSN23535 | C-178 | 329198-87-0 | C-178 is a STING inhibitor that can block palmitoylation (PMA)-induced clustering of STING. |
CSN22907 | C-176 | 314054-00-7 | C-176 is a STING inhibitor with anti-inflammatory effection. |
CSN23676 | H-151 | 941987-60-6 | 1-(4-Ethylphenyl)-3-(1H-indol-3-yl)urea, also known as H-151, is a irreversible inhibitor of STING that can inhibit the type I interferon (IFN) response and reduce the phosphorylation of TBK1 and palmitoylation of human STING in vitro. |
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