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STING

STING

货号 产品名 CAS号 信息
CSN19006 ML RR-S2 CDA Ammonium 1638750-96-5 ML RR-S2 CDA ammonium is an inducer of STING (stimulator of interferon genes). ML RR-S2 CDA has enhanced binding affinity to STING and activate all known human STING alleles.
CSN27873 ChX710   2438721-44-7 ChX710 can boost cellular response to cytosolic DNA via STING. It efficiently primed cellular response to transfected plasmid DNA as assessed by potent synergistic effects on IFN-β secretion and ISG expression levels.
CSN18467 cGAMP 849214-04-6 cGAMP, an endogenous second messenger, can induce the formation of cytokines and promote innate immune response. It also acts as an activator of STING with antitumor activity.
CSN22894 CCCP 555-60-2 CCCP can inhibit the activation of STING and is widely used as a protonophore uncoupling agent for oxidative phosphorylation.
CSN23535 C-178 329198-87-0 C-178 is a STING inhibitor that can block palmitoylation (PMA)-induced clustering of STING.
CSN22907 C-176 314054-00-7 C-176 is a STING inhibitor with anti-inflammatory effection.
CSN23676 H-151 941987-60-6 1-(4-Ethylphenyl)-3-(1H-indol-3-yl)urea, also known as H-151, is a irreversible inhibitor of STING that can inhibit the type I interferon (IFN) response and reduce the phosphorylation of TBK1 and palmitoylation of human STING in vitro.
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