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Trace amine-associated receptors are a class of G-protein-coupled receptors, identified in human (six subtypes) and other vertebrates and invertebrates.
| 货号 | 产品名 | CAS号 | 信息 |
|---|---|---|---|
| CSN25153 | 2-(1H-Indol-3-yl)ethanamine | 61-54-1 | Tryptamine is a monoamine alkaloid and may play a role as a neuromodulator or neurotransmitter. It is an agonist of hTAAR1. It acts as a non-selective serotonin receptor agonist and serotonin-norepinephrine-dopamine releasing agent (SNDRA). |
| CSN26560 | SEP-363856 | 1310426-33-5 | SEP-363856 （SEP-856）, an orally active and CNS active psychotropic agent with a unique, non-D2/5-HT2A mechanism of action, exerts its antipsychotic-like effects. SEP-363856 （SEP-856） has the potential for the treatment of schizophrenia[1]. |
| CSN26364 | RO5263397 | 1357266-05-7 | RO5263397 is a potent, selective, and orally available TAAR1 agonist, with EC50s of 17 and 35 nM for human TAAR1 and rat TAAR1, respectively. RO5263397 regulates wakefulness and EEG spectral composition and shows antidepressant-like effect[1][2][3]. |
| CSN26256 | RO5256390 | 1043495-96-0 | RO5256390 is an agonist of trace amine-associated receptor 1 (TAAR1), a highly conserved G-protein-coupled receptor (GPCR) bound by endogenous trace amines. RO5256390 blocks psychostimulant-induced hyperactivity and produces a brain activation pattern reminiscent of the antipsychotic drug olanzapine, suggesting antipsychotic-like properties. |
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