Tie-2 | Protein Tyrosine Kinase/RTK| CSNpharm

Tie-2

Tie-2
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货号	产品名	CAS号	信息
CSN16555	Tie2 kinase inhibitor 1	948557-43-5	Tie2 kinase inhibitor is an optimized compound of SB-203580, selective to Tie2 with IC50 of 0.25 μM, 200-fold more potent than p38.
CSN26565	GW768505A free base	501693-25-0	GW768505A free base is a potent dual inhibitor of VEGFR2 (KDR) and Tie-2, with a pIC50 of 7.81 for VEGFR2. GW768505A free base has anti-angiogenic activity[1]。
CSN15710	Cabozantinib	849217-68-1	Cabozantinib is a potent VEGFR2 inhibitor with IC50 of 0.035 nM and also inhibits c-Met, Ret, Kit, Flt-1/3/4, Tie2, and AXL with IC50 of 1.3 nM, 4 nM, 4.6 nM, 12 nM/11.3 nM/6 nM, 14.3 nM and 7 nM, respectively.
CSN22221	BAY-826	1448316-08-2	BAY-826 is a selective and potent TIE-2 inhibitor with Kdof 1.6 nM, respectively.
CSN90065	Nesvacumab	1296818-77-3
CSN51566	(S)-5-(4-(((2-((1-Cyclohexylethyl)amino)-2-oxoethyl)((p-tolyloxy)carbonyl)amino)methyl)phenyl)nicotinic acid	1020412-97-8