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TLR

TLR

货号 产品名 CAS号 信息
CSN42212 VB-201 630112-41-3 VB-201 is a Toll-like receptor-2 (TLR-2) antagonist.
CSN42525 TLR7/8 Agonist 1 1258457-59-8 TLR7/8 Agonist 1 is a dual agonist of TLR7/8 with EC50 values of 50nM and 55nM, respectively. It can be used as an immune stimulator.
CSN24480 TLR7/8 agonist 1 dihydrochloride 1620278-72-9 TLR7/8 agonist 1 dihydrochloride is a toll-like receptor (TLR7)/TLR8 dual-agonistic imidazoquinoline, showing substantially different agonistic potencies in human TLR7 (50 nM) and TLR8 (55 nM) primary screens
CSN26562 SM-276001 473930-22-2 SM-276001 is a selective and potent TLR7 agonist. SM-276001 is can induce antitumor immune responses when dosed either intratracheally or orally. Oral administration of SM-276001 leads to the induction of IFNα, TNFα and IL-12p40 and a reduction in tumor burden in the Balb/c syngeneic Renca and CT26 models.
CSN33189 Selgantolimod 2004677-13-6 Selgantolimod is a Potent and Selective Oral Toll-Like Receptor 8 Agonist for the Treatment of Chronic Hepatitis B.
CSN26372 Robinin 301-19-9 Robinin is flavonoid fraction of Vigna unguiculata leaf. Robinin inhibits upregulated expression of TLR2 and TLR4 and ameliorates oxidized low density lipoprotein (Ox-LDL) induced inflammatory insult through TLR4/NF-κB pathway[1].
CSN26358 Loxoribine 121288-39-9 Loxoribine, a guanosine analog, is selective agonist of Toll-like receptor 7 with anti-viral and anti-tumor activities.
CSN26529 GSK2245035 1207629-49-9 GSK2245035 is a selective Toll-like receptor 7 (TLR7) agonist with preferential Type-1 interferon (IFN)-stimulating properties. GSK2245035 displays extraordinary IFNα inducing potency and IFNα/TNFα selectivity. GSK2245035 shows excellent pharmaceutical properties that allow reliable delivery of doses as low as 1 ng per actuation of an intranasal spray formulation. Intranasal GSK2245035 has an acceptable safety profile at doses that induce local TLR7-mediated immune responses.
CSN24481 Gardiquimod diTFA 1159840-61-5 Gardiquimod trifluoroacetate is a specific TLR7 agonist.
CSN33123 Eritoran tetrasodium 185954-98-7 Eritoran Tetrasodium is a TLR4 receptor antagonist potentially for the treatment of type 2 diabetes.
CSN33122 3-O-Decyl-2-deoxy-6-O-[2-deoxy-3-O-[(3R)-3-methoxydecyl]-6-O-methyl-2-[[(11Z)-1-oxo-11-octadecenyl]amino]-4-O-phosphono-beta-D-glucopyranosyl]-2-[(1,3-dioxotetradecyl)amino]-alpha-D-glucopyranose1-(dihydrogenphosphat 185955-34-4 Eritoran is a TLR4 receptor antagonist.
CSN26779 CL264 1510712-69-2 CL264 is a TLR7-specific agonist for innate immune signals research[1].
CSN50330 Afimetoran 2171019-55-7 Afimetoran is an Oral Novel Toll-like Receptor 7 and 8 (TLR7/8) Inhibitor.
CSN26778 3M-011 642473-62-9 3M-011 is a potent dual toll-like receptor TLR7/8 agonist and a cytokine inducer. 3M-011 significantly inhibits H3N2 influenza viral replication in the nasal cavity. 3M-011 is also a potent adjuvant to radiotherapy that induces local and profound systemic immune responses during radiotherapy. 3M-011 strongly has antitumor action[1][2][3].
CSN22643 25-Hydroxycholesterol 2140-46-7 25-Hydroxycholesterol is a potent and selective suppressor of IgA production by B cells wit EC50 about 65 nM.
CSN28810 Polyinosinic-polycytidylic acid sodium 42424-50-0
CSN38026 AXC-715 hydrochloride 2490497-93-1
CSN37978 Chitohexaose hexahydrochloride 127171-88-4
CSN35473 TLR7 agonist 1 2178156-33-5
CSN50335 LHC-165 1258595-14-0
CSN50538 AXC 715 313350-31-1
CSN50640 3H-1-Benzazepine-4,8-dicarboxamide, 2-amino-N8-[6-[4-[[(2-aminoethyl)amino]carbonyl]-1-piperidinyl]-3-pyridinyl]-N4,N4-dipropyl- (ACI) 2244132-76-9
CSN50638 Ethyl 8-bromo-2-[(tert-butoxycarbonyl)amino]-3H-benzo[b]azepine-4-carboxylate 926927-57-3
CSN50633 AXC-715 trihydrochloride 2479276-17-8
CSN50639 2-Amino-N8-[5-(aminomethyl)-3-pyridinyl]-N4,N4-dipropyl-3H-1-benzazepine-4,8-dicarboxamide 1998726-22-9
CSN50632 Ethyl 2-amino-7-bromo-3H-1-benzazepine-4-carboxylate 1384958-64-8
CSN50637 1,1-Dimethylethyl N-[8-bromo-4-[(dipropylamino)carbonyl]-3H-1-benzazepin-2-yl]carbamate 1226791-82-7
CSN50631 8-Bromo-2-[[(1,1-dimethylethoxy)carbonyl]amino]-3H-1-benzazepine-4-carboxylic acid 1226791-81-6
CSN50635 Interferon Inducer 23 853792-81-1
CSN50636 FcyB ligand 16h 1784430-81-4
CSN50634 Interferon Inducer 22 853792-80-0
CSN62012 Kdo2-Lipid A ammonium 1246298-62-3
CSN62477 TLR8 agonist 2 2412937-64-3
CSN68241 Enpatoran hydrochloride 2101945-93-9
CSN67948 TLR7/8/9-IN-1 2180127-82-4
CSN68020 Guretolimod 1488364-57-3
CSN68026 BBIQ 1229024-57-0
CSN67448 TLR7/8-IN-1 2205095-75-4
CSN68193 TLR7 agonist 3 1229024-78-5
CSN72310 GSK1795091 1233589-81-5
CSN74289 2-(9-Chloro-2,3-dimethyl-6H-indolo[2,3-b]quinoxalin-6-yl)-N-(2-(dimethylamino)ethyl)acetamide 872178-65-9
CSN75303 Magnesium citrate 3344-18-1
CSN78077 TLR7/8 agonist 6 2115702-83-3
CSN79739 sodium (((1R)-1-carboxylato-2-(((E)-3,7,11,15-tetramethylhexadec-2-en-1-yl)thio)ethyl)carbamoyl)-L-prolinate 2234902-05-5
CSN78503 Polvitolimod 2389988-81-0
CSN80402 TLR8 agonist 2 hydrochloride 2412937-65-4
CSN79348 Guignardone L 1821386-10-0
CSN79405 TL8-506 1268163-15-0
CSN105069 6,7-Dimethoxy-2-(4-(4-methylpiperazin-1-yl)phenyl)-N-(2-morpholinoethyl)quinazolin-4-amine 1093135-60-4
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