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TLR

TLR

货号 产品名 CAS号 信息
CSN42212 VB-201 630112-41-3 VB-201 is a Toll-like receptor-2 (TLR-2) antagonist.
CSN20478 TLR2-IN-C29 363600-92-4 TLR2-IN-C29 is an inhibitor of TLR2.
CSN27285 TH 1020   1841460-82-9 TH1020 is Toll-like receptor (TLR) 5/Flagellin complex antagonist with IC50 of 0.85 μM. TH1020 competes with flagellin for TLR5 binding to inhibit the TLR5:flagellin interaction and subsequent downstream TNF-α secretion.
CSN26372 Robinin 301-19-9 Robinin is flavonoid fraction of Vigna unguiculata leaf. Robinin inhibits upregulated expression of TLR2 and TLR4 and ameliorates oxidized low density lipoprotein (Ox-LDL) induced inflammatory insult through TLR4/NF-κB pathway[1].
CSN19974 Polygalasaponin F 882664-74-6 Polygalasaponin F, a natural product isolated and purified from the herbs of Polygala japonica Houtt.
CSN27297 Pam3CSK4   112208-00-1 Pam3CSK4 is a toll-like receptor 1/2 (TLR1/2) agonist with an EC50 of 0.47 ng/mL for human TLR1/2 .
CSN21351 MD2-IN-1 111797-22-9 MD2-IN-1 is an inhibitor of Myeloid differentiation protein 2 (MD2) with a KD of 189  μM for the recombinant human MD2 (rhMD2).
CSN26358 7-Allyl-78-dihydro-8-oxoguanosine 121288-39-9 Loxoribine, a guanosine analog, is selective agonist of Toll-like receptor 7 with anti-viral and anti-tumor activities.
CSN24299 IAXO-102 1115270-63-7 IAXO-102 is a novel small molecule TLR4 antagonist.
CSN25649 Hydroxychloroquine 118-42-3 Hydroxychloroquine is an antimalarial agent used for the treatment of systemic lupus erythematosus, rheumatoid arthritis and other autoimmune, inflammatory and dermatologic conditions. Also acts as an inhibitor of autophagy and toll-like receptor (TLR)7/9.
CSN20270 G2013 1986-15-8 G2013 is a compoudn immunomodulatory effect on TLR2 and TLR4 in human mononuclear cells.
CSN21226 CU-CPT-8m 125079-83-6 CU-CPT8m is a Toll-like receptor 8 (TLR8) specific small-molecule inhibitor that exerts “potent anti-inflammatory effects” on the tissue of patients with arthritis.
CSN22764 CL 075 256922-53-9 CL 075 is a TLR8 agonist.
CSN22734 C34 40592-88-9 C34 is a TLR4 inhibitor.
CSN25419 Bropirimine 56741-95-8 Bropirimine is a synthetic agonist for toll-like receptor 7 (TLR7). Bropirimine inhibits differentiation of osteoclast precursor cells into osteoclasts via TLR7-mediated production of IFN-β. Bropirimine is an orally active immunomodulator that has demonstrated anticancer activity in transitional cell carcinoma in situ (CIS) in both the bladder and upper urinary tract.
CSN28448 AT791 1219962-49-8 AT791 inhibits TLR7/9 signaling in a variety of human and mouse cell types and inhibit DNA-TLR9 interaction in vitro. It suppresses responses to challenge doses of CpG–containing DNA.
CSN22347 AN-3485 1213827-99-6 AN-3485 is a benzoxaborole analog, Toll-Like Receptor(TLR) inhibitor with IC50 values ranging from 18 to 580 nM.
CSN38026 AXC-715 3HCl 2490497-93-1
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