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TLR

TLR

货号 产品名 CAS号 信息
CSN42212 VB-201 630112-41-3 VB-201 is a Toll-like receptor-2 (TLR-2) antagonist.
CSN42525 TLR7/8 Agonist 1 1258457-59-8 TLR7/8 Agonist 1 is a dual agonist of TLR7/8 with EC50 values of 50nM and 55nM, respectively. It can be used as an immune stimulator.
CSN24480 TLR7/8 agonist 1 2HCl 1620278-72-9 TLR7/8 agonist 1 dihydrochloride is a toll-like receptor (TLR7)/TLR8 dual-agonistic imidazoquinoline, showing substantially different agonistic potencies in human TLR7 (50 nM) and TLR8 (55 nM) primary screens
CSN26562 SM-276001 473930-22-2 SM-276001 is a selective and potent TLR7 agonist. SM-276001 is can induce antitumor immune responses when dosed either intratracheally or orally. Oral administration of SM-276001 leads to the induction of IFNα, TNFα and IL-12p40 and a reduction in tumor burden in the Balb/c syngeneic Renca and CT26 models.
CSN33189 Selgantolimod 2004677-13-6 Selgantolimod is a Potent and Selective Oral Toll-Like Receptor 8 Agonist for the Treatment of Chronic Hepatitis B.
CSN26372 Robinin 301-19-9 Robinin is flavonoid fraction of Vigna unguiculata leaf. Robinin inhibits upregulated expression of TLR2 and TLR4 and ameliorates oxidized low density lipoprotein (Ox-LDL) induced inflammatory insult through TLR4/NF-κB pathway[1].
CSN41470 Pam3CSK4 TFA 112208-01-2 Pam3CSK4 TFA is a trifluoroacetate form of Pam3CSK4. Pam3CSK4 is a toll-like receptor 1/2 (TLR1/2) agonist with an EC50 of 0.47 ng/mL for human TLR1/2 .
CSN26358 Loxoribine 121288-39-9 Loxoribine, a guanosine analog, is selective agonist of Toll-like receptor 7 with anti-viral and anti-tumor activities.
CSN26529 GSK2245035 1207629-49-9 GSK2245035 is a selective Toll-like receptor 7 (TLR7) agonist with preferential Type-1 interferon (IFN)-stimulating properties. GSK2245035 displays extraordinary IFNα inducing potency and IFNα/TNFα selectivity. GSK2245035 shows excellent pharmaceutical properties that allow reliable delivery of doses as low as 1 ng per actuation of an intranasal spray formulation. Intranasal GSK2245035 has an acceptable safety profile at doses that induce local TLR7-mediated immune responses.
CSN33123 Eritoran tetrasodium 185954-98-7 Eritoran Tetrasodium is a TLR4 receptor antagonist potentially for the treatment of type 2 diabetes.
CSN33122 Eritoran 185955-34-4 Eritoran is a TLR4 receptor antagonist.
CSN26779 CL264 1510712-69-2 CL264 is a TLR7-specific agonist for innate immune signals research[1].
CSN50330 Afimetoran 2171019-55-7 Afimetoran is an Oral Novel Toll-like Receptor 7 and 8 (TLR7/8) Inhibitor.
CSN26778 3M-011 642473-62-9 3M-011 is a potent dual toll-like receptor TLR7/8 agonist and a cytokine inducer. 3M-011 significantly inhibits H3N2 influenza viral replication in the nasal cavity. 3M-011 is also a potent adjuvant to radiotherapy that induces local and profound systemic immune responses during radiotherapy. 3M-011 strongly has antitumor action[1][2][3].
CSN22643 (3S,8S,9S,10R,13R,14S,17R)-17-((R)-6-Hydroxy-6-methylheptan-2-yl)-10,13-dimethyl-2,3,4,7,8,9,10,11,12,13,14,15,16,17-tetradecahydro-1H-cyclopenta[a]phenanthren-3-ol 2140-46-7 25-Hydroxycholesterol is a potent and selective suppressor of IgA production by B cells wit EC50 about 65 nM.
CSN28810 Polyinosinic-polycytidylic acid sodium 42424-50-0
CSN38026 AXC-715 HCl 2490497-93-1
CSN37978 Chitohexaose hexaHCl 127171-88-4
CSN35473 TLR7 agonist 1 2178156-33-5
CSN50335 LHC-165 1258595-14-0
CSN50538 1-(4-Aminobutyl)-2-butyl-1H-imidazo[4,5-c]quinolin-4-amine 313350-31-1
CSN50640 2-Amino-N8-(6-(4-((2-aminoethyl)carbamoyl)piperidin-1-yl)pyridin-3-yl)-N4,N4-dipropyl-3H-benzo[b]azepine-4,8-dicarboxamide 2244132-76-9
CSN50638 Ethyl 8-bromo-2-[(tert-butoxycarbonyl)amino]-3H-benzo[b]azepine-4-carboxylate 926927-57-3
CSN50633 AXC-715 3HCl 2479276-17-8
CSN50639 2-Amino-N8-(5-(aminomethyl)pyridin-3-yl)-N4,N4-dipropyl-3H-benzo[b]azepine-4,8-dicarboxamide 1998726-22-9
CSN50632 Ethyl 2-amino-7-bromo-3H-1-benzazepine-4-carboxylate 1384958-64-8
CSN50637 1,1-Dimethylethyl N-[8-bromo-4-[(dipropylamino)carbonyl]-3H-1-benzazepin-2-yl]carbamate 1226791-82-7
CSN50631 8-Bromo-2-[[(1,1-dimethylethoxy)carbonyl]amino]-3H-1-benzazepine-4-carboxylic acid 1226791-81-6
CSN50635 Interferon Inducer 23 853792-81-1
CSN50636 FcyB ligand 16h 1784430-81-4
CSN50634 Interferon Inducer 22 853792-80-0
CSN62012 Kdo2-Lipid A ammonium 1246298-62-3
CSN62477 TLR8 agonist 2 2412937-64-3
CSN68241 Enpatoran HCl 2101945-93-9
CSN67948 TLR7/8/9-IN-1 2180127-82-4
CSN68020 Guretolimod 1488364-57-3
CSN68026 BBIQ 1229024-57-0
CSN67448 TLR7/8-IN-1 2205095-75-4
CSN68193 TLR7 agonist 3 1229024-78-5
CSN72310 GSK1795091 1233589-81-5
CSN74289 Rabeximod 872178-65-9
CSN75303 Magnesium citrate 3344-18-1
CSN78077 TLR7/8 agonist 6 2115702-83-3
CSN79739 SIG1459 2234902-05-5
CSN78503 Polvitolimod 2389988-81-0
CSN80402 TLR8 agonist 2 HCl 2412937-65-4
CSN79348 Guignardone L 1821386-10-0
CSN79405 TL8-506 1268163-15-0
CSN105069 CPG-52364 1093135-60-4
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