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Tyrosinase

Tyrosinase

货号 产品名 CAS号 信息
CSN14855 Verminoside 50932-19-9 Verminoside, a natural product isolated and purified from the barks of Kigelia pinnata with anti-inflammatory effect, inhibits both iNOS expression and NO release in the LPS-induced J774.A1 macrophage cell line.
CSN24920 Tropolone 533-75-5 Tropolone inhibits both mono-and o-dihydroxyphenolase activity of mushroom tyrosinase.
CSN19343 Tricin 520-32-1 Tricin, a natural product isolated and purified from the herb of Avena sativa, is evaluated as a type of tyrosinase inhibitor, exerts anti-inflammatory effect via a mechanism involving the TLR4/NF-κB/STAT signaling cascade, may be beneficial in HSC-targeting therapeutic or chemopreventive applications for hepatic fibrosis, and is with potential anti-HCMV activity and that CXCL11 is one of the chemokines involved in HCMV replication.
CSN19971 Sweroside 14215-86-2 Sweroside, a natural product isolated and purified from the herbs of Swertia bimaculata with strong hepatoprotective, anti-osteoporotic, insulin-mimicking, and wound-healing effects, can inhibit potent melanogenesis in melan-a cells at 300uM without cytotoxicity, also decreases tyrosinase, tyrosinase-related protein-1 (TRP-1) and TRP-2 protein production in melan a cells.
CSN14818 Steppogenin 56486-94-3 Steppogenin is a natural prodcut isolated and purified from the stems of Cudrania tricuspidata with cytotoxicity and significant tyrosinase inhibition activity.
CSN14296 Pedalitin 22384-63-0 Pedalitin is a natural mixed-type inhibitor of tyrosinase isolated and purified from the herbs of Rabdosia rubescens, and is also a competitive inhibitor of α-glucosidase.
CSN12329 Oxyresveratrol 29700-22-9 Oxyresveratrol is a naturallly occuring stilbenoid found in the heartwood of Artocarpus lakoocha, which works as a potent tyrosinase inhibitor and also possesses anti-proliferative, anti-inflammatory, and cardioprotective properties.
CSN24998 Methyl cinnamate 103-26-4 Methyl cinnamate is the methyl ester of cinnamic acid found naturally in a variety of plants. It could be used in the flavor and perfume industries.
CSN27575 Isoastilbin   54081-48-0 Isoastilbin is a dihydroflavonol glycoside compound in Rhizoma Smilacis glabrae and Astragalus membranaceus. Isoastilbin inhibits glucosyltransferase (GTase) with an IC50 value of 54.3 μg/mL, and also inhibits tyrosinase activity. Isoastilbin shows neuroprotective, antioxidation, antimicrobial and anti-apoptotic properties and has the potential for Alzheimer’s disease research.
CSN22606 Gnetol 86361-55-9 Gnetol is a tyrosinase inhibitor isolated from genus Gnetum.
CSN25194 Glycolic acid 79-14-1 Glycolic acid (or hydroxyacetic acid) is the smallest alpha-hydroxy acid. Due to its excellent capability to penetrate skin, glycolic acid is often used in skin care products, most often as a chemical peel.
CSN14614 Glabrene 60008-03-9 Glabrene, a natural product isolated and purified from the roots of Glycyrrhiza uralensis with estrogen-like activity, can stimulate DNA synthesis in human endothelial cells (ECV-304; E304) and has a bi-phasic effect on proliferation of human vascular smooth muscle cells (VSMC), exerts varying degrees of inhibition on tyrosinase-dependent melanin biosynthesis, suggesting that it may serve as candidates for skin-lightening agents.
CSN24311 Fumaric Acid 110-17-8 Fumaric acid a reversible inhibitor of tyrosinase.
CSN12905 Deoxyarbutin 53936-56-4 Deoxyarbutin is a reversible inhibitor of tyrosinase with IC50 of 50 nM.
CSN14294 Dalbergioidin 30368-42-4 Dalbergioidin, a natural product isolated and purified from the roots of Parochetus communis with tyrosinase inhibitory activity with an IC50 of 20 mM, shows a melanin biosynthesis inhibition zone in the culture plate of Streptomyces bikiniensis that has commonly been used as an indicator organism, protects MC3T3-E1 osteoblastic cells against H2O2-induced cell damage through activation of the PI3K/AKT/SMAD1 pathway, and ameliorates doxorubicin-induced renal fibrosis by suppressing the TGF-β signal pathway.
CSN14069 beta-Hydroxypropiovanillone 2196-18-1 beta-Hydroxypropiovanillone is a natural product isolated and purified from the barks of Pinus yunnanensis showing potent tyrosinase inhibitory activity.
CSN24117 Benzylacetone 2550-26-7 Benzylacetone is an aromatic compound from agarwood[1]. Benzylacetone exhibits potent and reversible antityrosinase (mushroom) activity， with IC50s of 2.8 mM and 0.6 mM for monophenolase and diphenolase, respectively[2]. Benzylacetone has appetite-enhancing and locomotor-reducing effects[3].
CSN11495 Arbutin 497-76-7 Arbutin is an inhibitor of tyrosinase with IC50 of 1.09 mM and can prevent the formation of melanin. It is a glycosylated hydroquinone found in the leaves of arctostaphylos uvaursi.
CSN11403 Aloin A 1415-73-2 Aloin A, an anthracycline from aloe plants, can be used as a chemopreventive factor with antineoplastic activity. It exhibits inhibition of phosphodiesterase and tyrosinase.
CSN23314 Aloesin 30861-27-9 Aloesin (Aloeresin) is an active constituent of the herb aloe vera and displays anti-inflammatory activity, ultraviolet protection, and antibacterium effects. Aloesin exerts its anticancer effect through the MAPK signaling pathway[1][2].
CSN25166 4-Methoxysalicylaldehyde 673-22-3 4-Methoxysalicylaldehyde, a naturally occurring product, has a range of industrial applications in the preparation of organic compounds, drugs and therapeutic agents.
CSN12535 4-Hexylbenzene-1,3-Diol 136-77-6 4-Hexylbenzene-1,3-Diol is a mushroom tyrosinase inhibitor with local anaesthetic and antiseptic activities.
CSN23351 4-Butylresorcinol 18979-61-8 4-Butylresorcinol, a phenol derivative, is an inhibit of tyrosinase with IC50 of 11.27 μM.
CSN29999 4-(1-Phenylethyl)benzene-1,3-diol 85-27-8 4-(1-Phenylethyl)benzene-1,3-diol is a tyrosinase inhibitor.
CSN27576 3,4-Dimethoxyphenol 2033-89-8 3,4-Dimethoxyphenol is a plant-derived phenylpropanoid compound and can use as a whitening agent in cosmetics. 3,4-Dimethoxyphenol has tyrosinase-inhibiting activity. 3,4-Dimethoxyphenol has potent antioxidant effect isolated from the bacterial fermentation broth.
CSN27574 3',4'-Dihydroxyacetophenone 1197-09-7 3',4'-Dihydroxyacetophenone (3,4-DHAP), isolated from Picea Schrenkiana Needles exhibits a strong suppressive action against tyrosinase activity, with an IC50 of 10 μM. 3',4'-Dihydroxyacetophenone (3,4-DHAP) is a vasoactive agent and antioxidant.
CSN25113 2-Ketoglutaric acid 328-50-7 2-Ketoglutaric acid, also known as alpha-ketoglutarate and AKG, is a key molecule in the TCA cycle, playing a fundamental role in determining the overall rate of this important metabolic process. In the TCA cycle, AKG is decarboxylated to succinyl-CoA and carbon dioxide by AKG dehydrogenase, which functions as a key control point of the TCA cycle.
CSN64530 Fumaric acid 110-17-8
CSN64514 2-Ketoglutaric acid 328-50-7
CSN26957 Kojic acid dipalmitate 79725-98-7
CSN26955 Palmitoyl Tripeptide-5 TFA 623172-56-5
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