CSN17383 |
TAK-593
|
1005780-62-0 |
TAK-593 is a potent and selective dual VEGFR/PDGFR inhibitor with IC50s of 3.2/0.95/1.1 nM (VEGFR1/2/3) and 4.3/1/13 nM (PDGFRα/PDGFRα V561D/PDGFRβ) and with an IC50 > 1 μM when tested against more than 200 protein and lipid kinases. |