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Wnt

Wnt

货号 产品名 CAS号 信息
CSN26794 β-catenin/CBP-IN-1 1198780-38-9 β-catenin/CBP-IN-1 is a potent and selective CBP/β-catenin antagonist, extracted from the patent WO2014092154A1. β-catenin/CBP-IN-1 has the potential for the study of liver fibrosis induced by hepatitis virus[1].
CSN13998 Xanthatin 26791-73-1 Xanthatin, a natural product isolated and purified from the fruits of Xanthium sibiricum with cytotoxic, antibacterial and antifungal activities, can inhibit murine melanoma B16-F10 cell proliferation possibly associated with activation of Wnt/β-catenin pathway and its activity against melanoma tumor might also be relevant to inhibition of angiogenesis.
CSN11885 Salinomycin 53003-10-4 Salinomycin, an antibiotic potassium ionophore, is an anti-coccidial drug and an autophagy modulator. It is also an inhibitor of Wnt/β-catenin signaling.
CSN19163 PNU-74654 113906-27-7 PNU-74654 is an inhibitor of Wnt/β-catenin pathway with an IC50 of 129.8 μM in NCI-H295 cell.
CSN11650 Pamidronic Acid 40391-99-9 Pamidronic Acid is a an amino- bisphosphonate used to prevent bone loss and treat osteoporosis.
CSN23011 NSC 668036 144678-63-7 NSC 668036 is a Wnt signaling inhibitor by binding the PDZ domain of the Dishevelled (Dvl) protein. It inhibits proliferation, migration and TGF-β-induced differentiation of fibroblasts in vitro.
CSN23594 Methyl Vanillate 3943-74-6 Methyl vanillate has ability to increase bone mass and activate wnt/β-catenin pathway. It can act as a potential lead anabolic agent for anti-osteoporosis drugs.
CSN13654 IWR-1-Endo 1127442-82-3 IWR-1-endo is a small-molecule inhibitor of Wnt signaling (IC50 of 180 nM in L-cells expressing Wnt3A) by stabilizing the Axin destruction complex with an EC50 of 0.2 μM.
CSN22864 IWP 4 686772-17-8 IWP 4 is a potent inhibitor of Wnt/β-catenin signaling with IC50 of 25 nM.
CSN12291 BML-284 853220-52-7 BML-284 is a Wnt signaling activator with EC50 value of 0.7 μM for inducing β-catenin and TCF-dependent transcriptional activity.
CSN19238 AMBMP HCl 2095432-75-8 AMBMP HCl is a cell permeable Wnt signaling pathway activator, which induces β-catenin- and TCF-dependent transcriptional activity with EC50 of 0.7 μM.
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