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Wnt
| 货号 | 产品名 | CAS号 | 信息 |
|---|---|---|---|
| CSN23594 | Methyl Vanillate | 3943-74-6 | Methyl vanillate has ability to increase bone mass and activate wnt/β-catenin pathway. It can act as a potential lead anabolic agent for anti-osteoporosis drugs. |
| CSN22542 | LF3 | 664969-54-4 | LF3 is an inhibitor of canonical wnt signaling pathway with IC50 of less than 2 μM. It can disrupt the interaction between β-catenin and TCF4. |
| CSN19247 | KYA1797K | 1956356-56-1 | KYA1797K is a highly potent and selective Wnt/β-catenin inhibitor with IC50 of 0.75 µM (TOPflash assay). |
| CSN22864 | IWP 4 | 686772-17-8 | IWP 4 is a potent inhibitor of Wnt/β-catenin signaling with IC50 of 25 nM. |
| CSN21406 | iCRT-3 | 901751-47-1 | iCRT3 can inhibit both Wnt and β-catenin-responsive transcription. |
| CSN16814 | iCRT 14 | 677331-12-3 | iCRT 14 is a potent inhibitor of β-catenin-responsive transcription (CRT) (IC50 = 40.3 nM in assays of Wnt pathway activity). Thought to directly influence the interaction between β-catenin and TCF4. Induces marked G0/G1 cell cycle arrest in HCT-116 and HT29 cell lines. |
| CSN22412 | Gigantol | 67884-30-4 | Gigantol is a bibenzyl compound derived from several medicinal orchids. Giganto shows promising therapeutic potential against cancer cells. Gigantol is a novel inhibitor of the Wnt/β-catenin pathway. |
| CSN17991 | CCT251545 | 1661839-45-7 | CCT251545 is an orally bioavailable and potent inhibitor of WNT signaling with IC50 value of 5 nM. |
| CSN22337 | Adavivint | 1467093-03-3 | Adavivint is a potent and selective inhibitor of canonical Wnt signaling, with an EC50 of 19.5 nM via a high-throughput TCF/LEF-reporter assay in SW480 colon cancer cells. |