|5-((E)-2-溴乙烯基)-1-((2R,4S,5R)-4-羟基-5-(羟甲基)四氢呋喃-2-基)嘧啶-2,4(1H,3H)-二酮|CsnPharm

CAS No.: 69304-47-8

(E)-5-(2-Bromovinyl)-2'-deoxyuridine/溴夫定 Catalog No. CSN10521

Synonyms: Bromovinyldeoxyuridine;BVDU;Bridic

Brivudine is an antiviral drug acts by inhibiting replication of the target virus, used in the treatment of Herpes Zoster.

规格	价格	促销价格	库存	数量

400-920-2911

sales@csnpharm.cn

tech@csnpharm.cn

加入购物车大规格询价

加入收藏

产品咨询

400-920-2911

sales@csnpharm.cn

tech@csnpharm.cn

纯度 & 质量文件批次:

靶点选择性

生物活性

实验方案

技术信息

生物活性

描述Brivudine is an analog of thymidine, and is incorporated into the viral DNA. It blocks the action of DNA polymerases, thus inhibiting viral replication. It has a stronger antiviral effect against the varicella-zoster virus compared with reference compounds such as aciclovir or penciclovir^[3]. It has high, selective activity against varicella zoster virus (VZV), inhibiting VZV replication, possibly through competitive inhibition of viral DNA polymerase, or by acting as an alternative substrate to deoxythymidine triphosphate, causing viral DNA strand breakage. Oral brivudin is generally well tolerated, with a similar tolerability profile to those of oral acyclovir or famciclovir. Nausea was the most commonly reported adverse event^[4]. As opposed to the others, brivudine is a non-nephrotoxic drug that should not be administered to immunodepressed patients or to those being treated with 5-fluorouracil^[5].
参考文献

实验方案

计算器摩尔计算器总药量计算器工作液计算器
储存液制备
- 1 mg
- 5 mg
- 10 mg
- 1 mM
- 3.0018 mL
- 15.0089 mL
- 30.0178 mL
- 5 mM
- 0.6004 mL
- 3.0018 mL
- 6.0036 mL
- 10 mM
- 0.3002 mL
- 1.5009 mL
- 3.0018 mL

技术信息

CAS号

69304-47-8

储存条件

粉末: Inert atmosphere,2-8°C

液体: -20°C:3-6 月 -80°C:12月

分子式

C11H13BrN2O5

运输

蓝冰

分子量

333.14

别名

Bromovinyldeoxyuridine;BVDU;Bridic;Brivox;Brivudin;Helpin ;Zerpex;Zonavir;and Zostex;RP-101;溴夫定

溶解度

DMSO	66.0 mg/mL (198.1 mM)

动物实验配方

大规格询价

号为必填项

姓名: 邮箱: 手机号:

留言:

提交

(E)-5-(2-Bromovinyl)-2'-deoxyuridine/溴夫定 Catalog No. CSN10521

靶点选择性

请登录您的专属账户

确认信息