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研究领域
癌症
心血管疾病
感染
代谢疾病
神经疾病
免疫/炎症
新产品更多
ADH-503
ADH-503 is a potent agonist of the integrin CD11b to mitigate myeloid cell immunosuppression.
Mc-Val-Ala-PAB
Mc-Val-Ala-PAB is a useful ADC linker conjugating for targeting drug delivery.
O-304
O-304 is a first-in-class, orally available pan-AMPK activator, which increases AMPK activity by suppressing the dephosphorylation of pAMPK. O-304 exhibits a great potential as a drug to treat type 2 diabetes (T2D) and associated cardiovascular complications [1][2].
AST2818 mesylate
AST2818 mesylate is an EGFR inhibitor.
CC-90011 besylate
CC-90011 is a potent and orally active LSD1 inhibitor. It is in phase I clinical study of CC-90011 in patients (pts) with advanced unresectable solid tumors and R/R NHL.
GSK-25
GSK-25 is a ROCK1 inhibitor with IC50 value of 6nM. It showed oral bioavailability (49% in rat and 19% in monkey), good half-life (1.8 h in rat and 2.2 h in monkey) and gave a robust 25 mmHg reduction mean arterial pressure in spontaneously hypertensive rats at a single dose of 30 mg/kg.
Adenosine amine congener
Adenosine amine congener hydrate is a potent aqueous-soluble A1 adenosine receptor agonist with Ki value of 0.85nM for binding against [3H]N6-cyclohexyladenosine in rat cerebral cortex membranes.
Emodepside
Emodepside is an antiparasitic that is effective against a number of gastrointestinal nematodes, used in cat.
Ibrolipim
Ibrolipim is a Lipoprotein lipase activator.
TLX agonist 1
TLX agonist 1 (ccrp2) is an orphan nuclear receptor tailless (TLX, NR2E1) modulator with EC50 of 1μM and Kd of 650 nM.
特色产品更多
Calcifediol
Cilengitide
CPI-0610
CFI-402257
Lifitegrast
GLPG1690
AZD0364
AMG-3969
WT161
AZD0156
UNBS5162
AZD1981
BMS-309403
AM-0902
Risdiplam
TUG-1375
GSK-2894631A
DDD107498