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1-乙基-(3-二甲基氨基丙基)碳二亚胺盐酸盐 /1-(3-Dimethylaminopropyl)-3-ethylcarbodiimide hydrochloride 99%

货号:A104599 产品仅供科研

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Type HazMat fee for 500 gram (Estimated)
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Limited Quantity USD 15-60
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1-(3-Dimethylaminopropyl)-3-ethylcarbodiimide hydrochloride 化学结构 CAS号:25952-53-8
1-(3-Dimethylaminopropyl)-3-ethylcarbodiimide hydrochloride 化学结构
CAS号:25952-53-8
1-(3-Dimethylaminopropyl)-3-ethylcarbodiimide hydrochloride 3D分子结构
CAS号:25952-53-8
1-(3-Dimethylaminopropyl)-3-ethylcarbodiimide hydrochloride 化学结构 CAS号:25952-53-8
1-(3-Dimethylaminopropyl)-3-ethylcarbodiimide hydrochloride 3D分子结构 CAS号:25952-53-8
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1-(3-Dimethylaminopropyl)-3-ethylcarbodiimide hydrochloride 纯度/质量文件

货号:A104599 标准纯度:99%
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1-(3-Dimethylaminopropyl)-3-ethylcarbodiimide hydrochloride 生物活性

描述 1-(3-Dimethylaminopropyl)-3-ethylcarbodiimide hydrochloride functions as a carbodiimide reagent capable of forming nucleic acids and compounds with amide bonds. It acts as a condensing and dehydrating agent, accelerating the formation of esters, amides, and peptides, frequently employed in the synthesis of polynucleotides, anhydroxydation, lactonization, and esterification[1].[2]. 1-(3-Dimethylaminopropyl)-3-ethylcarbodiimide hydrochloride (EDC•HCl) is particularly effective in forming amide bonds (peptide bonds) within aqueous environments[1]. 1-(3-Dimethylaminopropyl)-3-ethylcarbodiimide hydrochloride (EDC•HCl) is extensively applied in various scientific methods, including the preparation of polyaniline-carbon nanotube composites for cholesterol biosensors, precolumn derivatization of aliphatic amines for HPLC, creating molecular beacons for DNA research, developing sensors for calcium detection, determining carboxylic acids fluorescently, and performing solid-phase microsequencing of peptides[2]. As an inhibitor, 1-(3-Dimethylaminopropyl)-3-ethylcarbodiimide hydrochloride (EDC•HCl) targets aminoaldehyde dehydrogenase (AMADH), though its effect on glutamate decarboxylase (GAD) is minimal[3].

1-(3-Dimethylaminopropyl)-3-ethylcarbodiimide hydrochloride 参考文献

[1]Kunihiko Seno, et al. Spectrophotometric determination of 1-(3-dimethylaminopropyl)-3-ethylcarbodiimide hydrochloride by flow injection analysis. Anal Sci. 2008 Apr;24(4):505-8.

[2]Kunihiko Seno, et al. Determination of 1-(3-dimethylaminopropyl)-3-ethylcarbodiimide hydrochloride by flow-injection analysis based on a specific condensation reaction between malonic acid and ethylenediamine. Anal Sci. 2009 Mar;25(3):389-93.

[3]Runqiang Yang, et al. AMADH inhibitor optimization and its effects on GABA accumulation in soybean sprouts under NaCl-CaCl 2 treatment. 3 Biotech. 2019 May;9(5):184.

1-(3-Dimethylaminopropyl)-3-ethylcarbodiimide hydrochloride 实验方案

计算器
存储液制备 1mg 5mg 10mg

1 mM

5 mM

10 mM

5.22mL

1.04mL

0.52mL

26.08mL

5.22mL

2.61mL

52.16mL

10.43mL

5.22mL

1-(3-Dimethylaminopropyl)-3-ethylcarbodiimide hydrochloride 技术信息

CAS号25952-53-8
分子式C8H18ClN3
分子量191.702
别名
运输蓝冰
存储条件

粉末 Keep in dark place,Sealed in dry,Store in freezer, under -20°C

液体 -20°C:3-6个月-80°C:12个月

溶解度

DMSO: 60 mg/mL(312.99 mM),配合低频超声助溶,注意:DMSO长时间开封后,会吸水并导致溶解能力下降,请避免使用长期开封的DMSO

H2O: 100 mg/mL(521.64 mM),配合低频超声助溶

动物实验配方
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