CAS No.: 823198-78-3
2-((3-Methoxyphenyl)ethynyl)-6-methylpyridine hydrochloride Catalog No. CSN22913
MPEP HCl is both a selective non-competitive mGlu5 receptor antagonist with IC50 value of 36 nM, and a mGlu4 receptor positive allosteric modulator.
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纯度 & 质量文件
批次:
靶点选择性
生物活性
- 描述
- 参考文献
- [1] Chau P, Soderpalm B, et al. The mGluR5 antagonist MPEP elevates accumbal dopamine and glycine levels; interaction with strychnine-sensitive glycine receptors. Addict Biol. 2011 Oct;16(4):591-9.
- [2] Gasparini F, Lingenhohl K, et al. 2-Methyl-6-(phenylethynyl)-pyridine (MPEP), a potent, selective and systemically active mGlu5 receptor antagonist. Neuropharmacology. 1999 Oct;38(10):1493-503.
实验方案
- 计算器
- 储存液制备
技术信息
| CAS号 | 823198-78-3 | 储存条件 |
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| 分子式 | C15H14ClNO | 运输 | 蓝冰 | |
| 分子量 | 259.73 | 别名 |
