CAS No.: 1645286-58-3
AZ1366 Catalog No. CSN18861
AZ1366 inhibits tankyrase as a cotreatment strategy with EGFR inhibition in an identifiable subset of EGFR-driven NSCLC.
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纯度 & 质量文件
批次:
靶点选择性
生物活性
- 描述
- 参考文献
- [1] Scarborough HA, Helfrich BA, et al. AZ1366: An Inhibitor of Tankyrase and the Canonical Wnt Pathway that Limits the Persistence of Non-Small Cell Lung Cancer Cells Following EGFR Inhibition. Clin Cancer Res. 2017 Mar 15;23(6):1531-1541.
- [2] Quackenbush KS, Bagby S, et al. The novel tankyrase inhibitor (AZ1366) enhances irinotecan activity in tumors that exhibit elevated tankyrase and irinotecan resistance. Oncotarget. 2016 May 10;7(19):28273-85.
实验方案
- 计算器
- 储存液制备
技术信息
| CAS号 | 1645286-58-3 | 储存条件 |
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| 分子式 | C24H24N4O3 | 运输 | 蓝冰 | |
| 分子量 | 416.47 | 别名 |
