生物活性

• 描述BAY 1436032 is a potent, selective and orally available inhibitor of mutant Isocitrate Dehydrogenase 1 (mIDH1).
• 临床研究

• NCT号	适应症或疾病	临床期	招募状态	预计完成时间	地点
  NCT03127735	Leukemia, Myeloid, Acute	Phase 1	Active, not recruiting	October 11, 2019	United States, California ... more >> University of Southern California Keck School of Medicine Los Angeles, California, United States, 90033-9172 United States, Florida University of Florida-Gainesville Gainesville, Florida, United States, 32608 United States, Georgia Northside Hospital - Atlanta Atlanta, Georgia, United States, 30342 United States, Illinois Northwestern Memorial Hospital Chicago, Illinois, United States, 60611-2908 United States, New York Montefiore Medical Center Bronx, New York, United States, 10467-2490 Roswell Park Cancer Institute Buffalo, New York, United States, 14263-0001 Mount Sinai Medical Center New York, New York, United States, 10029 United States, North Carolina Wake Forest Baptist Health Winston-Salem, North Carolina, United States, 27157 United States, Ohio Ohio State University Columbus, Ohio, United States, 43210 United States, Pennsylvania University of Pennsylvania Philadelphia, Pennsylvania, United States, 19104 Thomas Jefferson University Philadelphia, Pennsylvania, United States, 19107 United States, Texas University of Texas MD Anderson Cancer Center Houston, Texas, United States, 77030 Germany Universitätsklinikum Heidelberg Heidelberg, Baden-Württemberg, Germany, 69120 Klinikum rechts der Isar München, Bayern, Germany, 81675 Medizinische Hochschule Hannover (MHH) Hannover, Niedersachsen, Germany, 30625 Universitätsklinikum Essen Essen, Nordrhein-Westfalen, Germany, 45122 Universitätsklinikum Leipzig AöR Leipzig, Sachsen, Germany Universitätsklinikum Charite zu Berlin Berlin, Germany, 12200 Universitätsklinikum Hamburg Eppendorf (UKE) Hamburg, Germany, 20246 Collapse <<
  NCT02746081	Solid Tumors	Phase 1	Active, not recruiting	June 3, 2019	United States, California ... more >> Los Angeles, California, United States, 90033 Santa Monica, California, United States, 90403 United States, Texas Houston, Texas, United States, 77030 United States, Virginia Charlottesville, Virginia, United States, 22908 Denmark Copenhagen, Denmark, 2100 Germany Heidelberg, Baden-Württemberg, Germany, 69120 Tübingen, Baden-Württemberg, Germany, 72076 München, Bayern, Germany, 81377 Frankfurt, Hessen, Germany, 60596 Essen, Nordrhein-Westfalen, Germany, 45147 Japan Nagoya, Aichi, Japan, 466-8560 Kashiwa-shi, Chiba, Japan, 277-8577 Chuo-ku, Tokyo, Japan, 104-0045 Collapse <<