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CAS No.: 1245792-67-9
BCI-215 is a hyperactivator of fibroblast growth factor signaling that is devoid of developmental toxicity and restores defective MAPK activity caused by overexpression of DUSP1 and DUSP6 in mammalian cells. BCI-215 induced rapid and sustained phosphorylation of extracellular signal-regulated kinase (ERK), p38, and c-Jun N-terminal kinase (JNK) in the absence of reactive oxygen species, and its toxicity was partially rescued by inhibition of p38 but not JNK or ERK.
生物活性
实验方案
技术信息
CAS号 | 1245792-67-9 | 储存条件 |
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分子式 | C22H22BrNO | 运输 | 蓝冰 | |||
分子量 | 396.32 | 别名 | ||||
溶解度 |
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动物实验配方 |
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