CAS No.: 56741-95-8
Bropirimine/溴匹立明 Catalog No. CSN25419
Synonyms: ABPP;NSC 149027;PNU 54461
Bropirimine is a synthetic agonist for toll-like receptor 7 (TLR7). Bropirimine inhibits differentiation of osteoclast precursor cells into osteoclasts via TLR7-mediated production of IFN-β. Bropirimine is an orally active immunomodulator that has demonstrated anticancer activity in transitional cell carcinoma in situ (CIS) in both the bladder and upper urinary tract.
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纯度 & 质量文件
批次:
靶点选择性
生物活性
- 参考文献
- [1] Suzuki H, et al. Bropirimine inhibits osteoclast differentiation through production of interferon-β. Biochem Biophys Res Commun. 2015;467(1):146‐151.
- [2] Sarosdy MF, et al. Oral bropirimine immunotherapy of bladder carcinoma in situ after prior intravesical bacille Calmette-Guérin. Urology. 1998;51(2):226‐231.
实验方案
- 计算器
- 储存液制备
技术信息
| CAS号 | 56741-95-8 | 储存条件 |
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| 分子式 | C10H8BrN3O | 运输 | 蓝冰 | |
| 分子量 | 266.09 | 别名 | ABPP;NSC 149027;PNU 54461;U-54461 |
