货号:A604243 同义名: Cerivastatin (sodium salt);BAY-w 6228 产品仅供科研
Cerivastatin, also known as BAY-w-6228, and Rivastatin, is a statins used to lower cholesterol and prevent cardiovascular disease. It was marketed by the pharmaceutical company Bayer A.G. in the late 1990s. Cerivastatin was voluntarily withdrawn from the market worldwide in 2001, due to reports of fatal rhabdomyolysis. During postmarketing surveillance, 52 deaths were reported in patients using Cerivastatin, mainly from rhabdomyolysis and its resultant renal failure.
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产品名称 | Ferroptosis ↓ ↑ | 其他靶点 | 纯度 | ||||||||||||||||
---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|
Ferrostatin-1 |
++
Ferroptosis, EC50: 60 nM |
98% | |||||||||||||||||
Liproxstatin-1 |
+++
ferroptosis, IC50: 22 nM |
99%+ | |||||||||||||||||
1. 鼠标悬停在“+”上可以显示相关IC50的具体数值。"+"越多,抑制作用越强。2. "✔"表示该化合物对相应的亚型有抑制作用,但抑制强度暂时没有相关数据。 |
计算器 | ||||
存储液制备 | 1mg | 5mg | 10mg | |
1 mM 5 mM 10 mM |
2.08mL 0.42mL 0.21mL |
10.38mL 2.08mL 1.04mL |
20.77mL 4.15mL 2.08mL |
CAS号 | 143201-11-0 |
分子式 | C26H33FNNaO5 |
分子量 | 481.532 |
别名 | Cerivastatin (sodium salt);BAY-w 6228 |
运输 | 蓝冰 |
存储条件 |
粉末 Inert atmosphere,2-8°C 液体 -20°C:3-6个月-80°C:12个月 |
溶解度 |
H2O: 100 mg/mL(207.67 mM),配合低频超声,并水浴加热至45℃助溶 |
动物实验配方 |