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CAS No.: 1061318-81-7
Synonyms: CUDC-305
Debio 0932 is a heat shock protein 90 (HSP90) inhibitor with strong affinity for HSP90 alpha/beta, high oral bioavailability and potent anti-proliferative activity against a broad range of cancer cell lines (with a mean IC50 of 220 nmol/L).
生物活性
NCT号 | 适应症或疾病 | 临床期 | 招募状态 | 预计完成时间 | 地点 |
---|---|---|---|---|---|
NCT03675542 | Psoriasis Vulgaris | Phase 1 | Not yet recruiting | February 1, 2020 | - |
NCT01168752 | Cancer Neopla... more >>sms Solid Tumors Lymphoma Collapse << | Phase 1 | Completed | - | France ... more >> Centre Georges-François Leclerc Dijon, France, 21079 Institut Claudius Regaud Toulouse, France, 31052 Institut Gustave Roussy Villejuif, France, 94805 Collapse << |
NCT01714037 | Non-small Cell Lung Cancer | Phase 1 | Terminated | - | France ... more >> Centre GF Leclerc Dijon, France Centre Léon Bérard Lyon, France Institut de Cancérologie de l'Ouest- Institut René Gauduchau Nantes, France Institut Claudius Regaud Toulouse, France Spain Hospital Universitari Vall d'Hebron Barcelona, Spain Hospital Puerta de Hierro Majadahonda Madrid, Spain Hospital Universitario Virgen del Rocío Seville, Spain United Kingdom Freeman Hospital Newcastle, United Kingdom Collapse << |
实验方案
技术信息
CAS号 | 1061318-81-7 | 储存条件 |
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分子式 | C22H30N6O2S | 运输 | 蓝冰 | |
分子量 | 442.58 | 别名 | CUDC-305 |
NCT号 | 适应症或疾病 | 临床期 | 招募状态 | 预计完成时间 | 地点 |
---|
NCT03675542 | Psoriasis Vulgaris | Phase 1 | Not yet recruiting | February 1, 2020 | - |
NCT01168752 | Cancer Neopla... more >>sms Solid Tumors Lymphoma Collapse << | Phase 1 | Completed | - | France ... more >> Centre Georges-François Leclerc Dijon, France, 21079 Institut Claudius Regaud Toulouse, France, 31052 Institut Gustave Roussy Villejuif, France, 94805 Collapse << |
NCT01714037 | Non-small Cell Lung Cancer | Phase 1 | Terminated | - | France ... more >> Centre GF Leclerc Dijon, France Centre Léon Bérard Lyon, France Institut de Cancérologie de l'Ouest- Institut René Gauduchau Nantes, France Institut Claudius Regaud Toulouse, France Spain Hospital Universitari Vall d'Hebron Barcelona, Spain Hospital Puerta de Hierro Majadahonda Madrid, Spain Hospital Universitario Virgen del Rocío Seville, Spain United Kingdom Freeman Hospital Newcastle, United Kingdom Collapse << |
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