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CAS No.: 2225887-26-1
Synonyms: EGFR-IN-5
EGFR-IN-5 is an inhibitor of EGFR with IC50 values of 10.4 nM, 1.1 nM, 34 nM and 7.2 nM for EGFR, EGFRL858R, EGFRL858R/T790M, and EGFRL858R/T790M/C797S, respectively. It could suppress EGFR phosphorylation in a dose-dependent manner in HCC827 cell line and significantly induce the apoptosis of HCC827 cells.
生物活性
实验方案
技术信息
CAS号 | 2225887-26-1 | 储存条件 |
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分子式 | C31H38FN9O | 运输 | 蓝冰 | |
分子量 | 571.69 | 别名 | EGFR-IN-5 |
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