|(S)-4-((S)-2-((S)-3-(1H-吲哚-3-基)-2-((S)-1-(((S)-5-氧代吡咯烷-2-甲酰基)甘氨酰)吡咯烷-2-甲酰胺)丙酰胺)-4-甲基戊酰胺)-5-(((S)-1-(((S)-1-(((S)-1-(((S)-1-(((S)-1-(((S)-1-(((4S,7S,10S,13S)-4-((1H-吲哚-3-基)甲基)-13-氨基甲酰基-10-(羧甲基)-7-(2-(甲硫基)乙基)-2,5,8,11-四氧代-14-苯基-3,6,9,12-四氮杂十四烷)氨基)-3-(4-羟基苯基)-1-氧代丙-2-基)氨基)-1-氧代丙-2-基)氨基)-4-羧基-1-氧代丁-2-基)氨基)-4-羧基-1-氧代丁-2-基)氨基)-4-羧基-1-氧代丁-2-基)氨基)-4-羧基-1-氧代丁-2-基)氨基)-5-氧代戊酸|CsnPharm

CAS No.: 10047-33-3

Gastrin I, human Catalog No. CSN21655

Synonyms: Gastrin I (human);Gastrin I (1-17) (human);Gastrin Heptadecapeptide I (human)

Gastrin I is an endogenous gastrointestinal peptide hormone that can bind to cholecystokinin (CCK) receptors.

规格	价格	促销价格	库存	数量

400-920-2911

sales@csnpharm.cn

tech@csnpharm.cn

加入购物车大规格询价

加入收藏

产品咨询

400-920-2911

sales@csnpharm.cn

tech@csnpharm.cn

纯度 & 质量文件批次:

靶点选择性

生物活性

实验方案

技术信息

生物活性

描述The peptide cholecystokinin (CCK), originally discovered in the gastrointestinal tract, has been shown to mediate pancreatic secretion and contraction of gallbladder. Two types of CCK receptors (CCK₁ found in the gut and CCK₂ found in the brain) have thus been distinguished. Gastrin-1, human, a endogenous peptide produced in the stomach, increases gastric acid secretion via acting at CCK₂ receptor^[1]. In anaesthetized rats, gastrin-1, human (1.5, 5, 15 and 45 nmol/kg, i.v.) increased both pepsinogen and acid secretion. After pretreatment with omeprazole, gastrin-1, human failed to stimulate acid secretion, while it increased pepsinogen output. In rats with gastric perfusion of acid solutions, gastrin-1, human increased peptic output in a pH-independent manner either with or without pretreatment with omeprazole^[2].
参考文献

[1] Noble F, et al. International Union of Pharmacology. XXI. Structure, distribution, and functions of cholecystokinin receptors. Pharmacol Rev. 1999 Dec;51(4):745-81
[2] Blandizzi C, et al. CCK1 and CCK2 receptors regulate gastric pepsinogen secretion. Eur J Pharmacol. 1999 May 28;373(1):71-84

实验方案

计算器摩尔计算器总药量计算器工作液计算器
储存液制备
- 1 mg
- 5 mg
- 10 mg
- 1 mM
- 0.4766 mL
- 2.3830 mL
- 4.7660 mL
- 5 mM
- 0.0953 mL
- 0.4766 mL
- 0.9532 mL
- 10 mM
- 0.0477 mL
- 0.2383 mL
- 0.4766 mL

技术信息

CAS号

10047-33-3

储存条件

粉末: Keep in dark place,Inert atmosphere,Store in freezer, under -20°C

液体: -20°C:3-6 月 -80°C:12月

分子式

C97H124N20O31S

运输

蓝冰

分子量

2098.20

别名

Gastrin I (human);Gastrin I (1-17) (human);Gastrin Heptadecapeptide I (human);Gastrin I;human

溶解度

DMSO	49.0 mg/mL (23.4 mM)

动物实验配方

大规格询价

号为必填项

姓名: 邮箱: 手机号:

留言:

提交

Gastrin I, human Catalog No. CSN21655

靶点选择性

请登录您的专属账户

确认信息