CAS No.: 6902-91-6
Germacrone Catalog No. CSN16452
Synonyms: (E,E)-Germacrone;Germacron
Germacrone, a natural product isolated and purified from the rhizoma of Curcuma wenyujin with anti-tumor activity, can inhibit the proliferation of breast cancer cell lines by inducing cell cycle arrest and apoptosis through mitochondria-mediated caspase pathway, and may be a potent chemopreventive drug candidate for liver cancer via regulating the expression of proteins related to G2/M cell cycle and apoptosis, and p53 and oxidative damage may play important roles in the inhibition of human hepatoma cells growth by germacrone.
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纯度 & 质量文件
批次:
靶点选择性
生物活性
- 描述
- 参考文献
- [1] An JF, Sun Y, et al. The effects of germacrone on lipopolysaccharide-induced acute lung injury in neonatal rats. Cell Mol Biol (Noisy-le-grand). 2014 Nov 16;60(4):8-12.
- [2] Xie XH, Zhao H, et al. Germacrone reverses Adriamycin resistance through cell apoptosis in multidrug-resistant breast cancer cells. Exp Ther Med. 2014 Nov;8(5):1611-1615. Epub 2014 Aug 26.
实验方案
- 计算器
- 储存液制备
技术信息
| CAS号 | 6902-91-6 | 储存条件 |
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| 分子式 | C15H22O | 运输 | 蓝冰 | |
| 分子量 | 218.33 | 别名 | (E,E)-Germacrone;Germacron |
