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CAS No.: 13115-71-4

Glycyl-glutamine Catalog No. CSN27548

Synonyms: Glycyl-L-glutamine;Gly-gln;L-Glutamine

Glycyl-glutamine (Glycyl-L-glutamine), as a enzymatic cleavage product of β-endorphin, is apparently an endogenous antagonist of beta-endorphin(1-31) in several systems. Glycyl-glutamine (Glycyl-L-glutamine) is an activate and stable glutamine-containing neuropeptide over glutamine (Gln).

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技术信息

生物活性

描述Glycyl-glutamine (Glycyl-L-glutamine), as a enzymatic cleavage product of β-endorphin, is apparently an endogenous antagonist of beta-endorphin(1-31) in several systems. Glycyl-glutamine (Glycyl-L-glutamine) (0.3, 0.6, 1.0 and 10.0 nM) can dose-dependently inhibit beta-End-(1-31)-induced hypotension in pentobarbital-anesthetized rats. Gly-L-gln also attenuated the respiratory depressant effect of beta-End-(1-31), significantly inhibiting beta-End-(1-31)-induced hypoxia and hypercapnia^[3]. Glycyl-glutamine (Glycyl-L-glutamine) is an activate and stable glutamine-containing neuropeptide over glutamine (Gln). Glycyl-glutamine (Glycyl-L-glutamine) has an advantage over free glutamine (Gln) as growth factors for cell culture during both autoclaving and storage^[4]. Intracerebroventricular injection of NPY (235 pmol) generated a hyperphagic response in ad libitum chicks within 30 min. Co-administration of Gly-Gln(glycyl-l-glutamine) (100 nmol) attenuated this response, inducing a 30 % decrease. Endogenous Gly-Gln may contribute to regulate feeding behavior via the central melanocortin system in chicks and acts as a counter regulator of the neural activity in energy metabolism^[5].
参考文献

实验方案

计算器摩尔计算器总药量计算器工作液计算器
储存液制备
- 1 mg
- 5 mg
- 10 mg
- 1 mM
- 4.9214 mL
- 24.6068 mL
- 49.2136 mL
- 5 mM
- 0.9843 mL
- 4.9214 mL
- 9.8427 mL
- 10 mM
- 0.4921 mL
- 2.4607 mL
- 4.9214 mL

技术信息

CAS号

13115-71-4

储存条件

粉末: Keep in dark place,Inert atmosphere,Room temperature

液体: -20°C:3-6 月 -80°C:12月

分子式

C7H13N3O4

运输

蓝冰

分子量

203.20

别名

Glycyl-L-glutamine;Gly-gln;L-Glutamine

溶解度

Water

60.0 mg/mL (295.3 mM) warming

动物实验配方

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