CAS No.: 957011-15-3
HBF-0259 Catalog No. CSN19764
HBF-0259 is an inhibitor of hepatitis B virus surface antigen (HBsAg) secretion. HBF-0259 was identified to inhibit HBsAg with an EC50 of 11.3 μM and a CC50 value of > 50 μM in HepG2.2.15 cells.
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纯度 & 质量文件
批次:
靶点选择性
生物活性
- 描述
- 参考文献
- [1] Yu W, Goddard C, et al. Design, synthesis, and biological evaluation of triazolo-pyrimidine derivatives as novel inhibitors of hepatitis B virus surface antigen (HBsAg) secretion. J Med Chem. 2011 Aug 25;54(16):5660-70.
- [2] Mohebbi A, Mohammadi S, Memarian A. Prediction of HBF-0259 interactions with hepatitis B Virus receptors and surface antigen secretory factors. Virusdisease. 2016 Sep;27(3):234-241.
实验方案
- 计算器
- 储存液制备
技术信息
| CAS号 | 957011-15-3 | 储存条件 |
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| 分子式 | C16H12Cl2FN5 | 运输 | 蓝冰 | |
| 分子量 | 364.20 | 别名 |
