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CAS No.: 1422365-93-2

Lixumistat Catalog No. CSN27189

Synonyms: HL156A

IM156 is a metformin derivative which has been reported to ameliorate various types of fibrosis and inhibit in vitro and in vivo tumors by inducing AMPK activation more potently than metformin. IM156 treatment impaired the function of virus-specific memory CD8+ T cells, indicating that excessive AMPK activation weakens memory T cell differentiation, thereby suppressing recall immune responses. IM156 activated AMPK in a dose-dependent manner, and produced shortening of the circadian period and enhanced degradation of the clock genes PER2 and CRY1.

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CAS号 1422365-93-2 储存条件
分子式 C13H16F3N5O 运输 蓝冰
分子量 315.29 别名 HL156A
溶解度
DMSO63.0 mg/mL (199.8 mM)
WaterInsoluble
Ethanol20.0 mg/mL (63.4 mM) warming
动物实验配方

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