CAS No.: 1395048-49-3
M-110 Catalog No. CSN17786
M-110 is a highly selective inhibitor of PIM kinases and inhibits the proliferation of prostate cancer cell lines with IC50s of 0.6 to 0.9 μM, with no activity on normal human peripheral blood mononuclear cells up to 40 μM.
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纯度 & 质量文件
批次:
靶点选择性
生物活性
- 描述
- 参考文献
- [1] He Y, Zhang Q, et al. Schisantherin A suppresses osteoclast formation and wear particle-induced osteolysis via modulating RANKL signaling pathways. Biochem Biophys Res Commun. 2014 Jul 4;449(3):344-50.
- [2] Zhou E, Li Y, et al. Schisantherin A protects lipopolysaccharide-induced acute respiratory distress syndrome in mice through inhibiting NF-κB and MAPKs signaling pathways. Int Immunopharmacol. 2014 Sep;22(1):133-40.
实验方案
- 计算器
- 储存液制备
技术信息
| CAS号 | 1395048-49-3 | 储存条件 |
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| 分子式 | C22H28ClN5O3 | 运输 | 蓝冰 | |
| 分子量 | 445.94 | 别名 |
