CAS No.: 939791-41-0
PF-562271 HCl/PF-562271盐酸盐 Catalog No. CSN19192
Synonyms: VS-6062(hydrochloride
PF-562271 HCl is the HCl salt of PF-562271, which is a potent, ATP-competitive, reversible inhibitor of FAK with IC50 of 1.5 nM, ~10-fold less potent for Pyk2 than FAK and > 100-fold selectivity against other protein kinases, except for some CDKs.
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纯度 & 质量文件
批次:
靶点选择性
生物活性
- 描述
- 参考文献
- [1] Roberts WG, Ung E, et al. Antitumor activity and pharmacology of a selective focal adhesion kinase inhibitor, PF-562,271. Cancer Res. 2008 Mar 15;68(6):1935-44.
- [2] Lim ST, Mikolon D, et al. FERM control of FAK function: implications for cancer therapy. Cell Cycle. 2008 Aug;7(15):2306-14. Epub 2008 May 29.
实验方案
- 计算器
- 储存液制备
技术信息
| CAS号 | 939791-41-0 | 储存条件 |
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| 分子式 | C21H21ClF3N7O3S | 运输 | 蓝冰 | |
| 分子量 | 543.95 | 别名 | VS-6062(hydrochloride |
