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CAS No.: 85547-56-4
Synonyms: 磷酸哌喹
Piperaquine is a bisquinoline compound that is often used in combination with artimesinin for inhibition of HIV-1 replication. It inhibits the ex vivo growth of P. falciparum isolates from malaria-infected patients with IC50s ranging from 11.8-217.3 nM.
生物活性
NCT号 | 适应症或疾病 | 临床期 | 招募状态 | 预计完成时间 | 地点 |
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NCT01838902 | Malaria | Phase 3 | Completed | - | Gambia ... more >> Medical Research Council Unit (MRC), The Gambia Fajara, Gambia Collapse << |
NCT02802501 | Malaria, Vivax | Phase 3 | Recruiting | November 29, 2019 | Indonesia ... more >> GSK Investigational Site Recruiting Jakarta, Indonesia, 10430 Contact: US GSK Clinical Trials Call Center 877-379-3718 GSKClinicalSupportHD@gsk.com Contact: EU GSK Clinical Trials Call Center +44 (0) 20 8990 4466 GSKClinicalSupportHD@gsk.com Collapse << |
NCT01288820 | Vivax Malaria | Phase 3 | Completed | - | Indonesia ... more >> Labuhan Batu Utara Regency Tanjung leidong village North Sumatra, North Sumatera, Indonesia Collapse << |
实验方案
技术信息
CAS号 | 85547-56-4 | 储存条件 |
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分子式 | C29H35Cl2N6O4P | 运输 | 蓝冰 | |
分子量 | 633.51 | 别名 | 磷酸哌喹 |
NCT号 | 适应症或疾病 | 临床期 | 招募状态 | 预计完成时间 | 地点 |
---|
NCT01838902 | Malaria | Phase 3 | Completed | - | Gambia ... more >> Medical Research Council Unit (MRC), The Gambia Fajara, Gambia Collapse << |
NCT02802501 | Malaria, Vivax | Phase 3 | Recruiting | November 29, 2019 | Indonesia ... more >> GSK Investigational Site Recruiting Jakarta, Indonesia, 10430 Contact: US GSK Clinical Trials Call Center 877-379-3718 GSKClinicalSupportHD@gsk.com Contact: EU GSK Clinical Trials Call Center +44 (0) 20 8990 4466 GSKClinicalSupportHD@gsk.com Collapse << |
NCT01288820 | Vivax Malaria | Phase 3 | Completed | - | Indonesia ... more >> Labuhan Batu Utara Regency Tanjung leidong village North Sumatra, North Sumatera, Indonesia Collapse << |
NCT02259426 | Malaria Asymp... more >>tomatic Malaria Plasmodium Falciparum Collapse << | Phase 3 | Completed | - | Kenya ... more >> ICIPE Mbita, Nyanza, Kenya, 30-40305 Collapse << |
NCT02324738 | Healthy | Phase 4 | Completed | - | Thailand ... more >> Faculty of Tropical Medicine Bangkok, Thailand, 10400 Collapse << |
NCT00393679 | Fever Malaria | Phase 3 | Completed | - | Burkina Faso ... more >> Centre Muraz/IRSS Bobo-Dioulasso, Burkina Faso Gabon Albert Schweitzer Hospital Lambaréné, Gabon Mozambique Manhiça Health Research Center Manhica, Mozambique Nigeria Hospital Calabar, Nigeria Rwanda Mashshesha and Rukara Kigali, Rwanda Uganda Jinja and Tororo Kampala, Uganda Mbarara, Mbarara, Uganda Zambia Tropical Diseases Research Centre, P O Box 71769, Ndola, Zambia Collapse << |
NCT00868465 | Uncomplicated Malaria | Not Applicable | Completed | - | Kenya ... more >> International Centre for Insect Physiology and Ecology - St. Judes Clinic Mbita, Suba District, Kenya Tanzania Kilimanjaro Christian Medical Centre, Magugu Field Site Moshi, Kilimanjaro Region, Tanzania Collapse << |
NCT02434952 | Malaria, Falciparum ... more >> G6PD Deficiency Collapse << | Phase 4 | Completed | - | Cambodia ... more >> Ratanakiri Provincial Hospital Ratanakiri, Cambodia Collapse << |
NCT03454048 | Malaria,Falciparum ... more >> Gametocytes Controlled Human Malaria Infection Transmission Collapse << | Not Applicable | Recruiting | December 1, 2018 | Netherlands ... more >> Radboud university medical center Recruiting Nijmegen, Gelderland, Netherlands, 6525 GA Contact: Isaie Reuling 024 361 9515 ext +31 isaie.reuling@radboudumc.nl Collapse << |
NCT01103830 | Malaria, Falciparum | Phase 1 | Completed | - | France ... more >> SGS aster s.a.s Paris, France, 75015 Collapse << |
NCT00941785 | Malaria | Phase 2 Phase 3 | Completed | - | Burkina Faso ... more >> IRSS Bobo-Dioulasso, Burkina Faso, BP545 Collapse << |
NCT03452475 | Plasmodium Falciparum | Phase 3 | Not yet recruiting | December 1, 2020 | - |
NCT02836002 | Malaria | Phase 1 Phase 2 | Completed | - | Netherlands ... more >> Radboud university medical center Nijmegen, Gelderland, Netherlands, 6525 GA Collapse << |
NCT02083380 | Uncomplicated Plasmodium Falci... more >>parum Malaria Collapse << | Phase 2 Phase 3 | Completed | - | Benin ... more >> Centre D'Étude Et de Recherchesur Le Paludisme Associé À La Grossesse Et À L'Enfance (Cerpage) Cerpage Cotonou, Benin, FSS 01 BP 188 Burkina Faso Centre National de Recherche et de Formation sur le paludisme (CNRFP) Ouagadougou, Kadiogo Ouagadougou, Burkina Faso Clinical research Unit of Nanoro (CRUN)/CMA Saint Camille de Nanoro, 11 BP 218 Ouagadougou CMS 11 Ouagadougou, Burkina Faso Congo, The Democratic Republic of the Kinshasa School of Public Health, School of Medicine University of Kinshasa Kinshasa, Congo, The Democratic Republic of the Gabon Centre de Recherches Medicales de Lambarene, Albert Schweitzer Hospital Lambarene, Gabon arielle K. Bouyou-Akotet, Department of Parasitology-Mycology and Tropical Medicine, Faculty of Medicine, Université des Sciences de la Santé, BP 4009, Libreville, Gabon Libreville, Gabon Mozambique MANHIÇA HEALTH RESEARCH CENTER, Rua 12, Vila da Manhica, Maputa, Chefe Maputa, Mozambique Uganda Tororo District Hospital Tororo, Uganda Vietnam National Institute of Malariology, Parasitology and Entomology, 245 Luong The Vinh Street, Trung van, Tu Liem, Hanoi, Vietnam Hanoi, Vietnam Collapse << |
NCT01887821 | Plasmodium Vivax Malaria | Phase 4 | Completed | - | Vietnam ... more >> Bu Gia Map Health Station Bu Gia Map, Binh Phuoc, Vietnam Collapse << |
NCT00852423 | Malaria in Pregnancy | Phase 3 | Completed | - | Burkina Faso ... more >> ISSR/Centre Muraz Nanoro, Burkina Faso ISSR/Centre Muraz Nazoanga, Burkina Faso Ghana Kwame Nkrumah University of Science & Technology, Kumasi Ejisu Sekyere East, Ashanti Region, Ghana Kwame Nrumah University of Science and Technology, Kumasi Juaben Government Hospital, Ashanti Region, Ghana Effiduase Government Hospital Effiduase, Ghana Malawi College of Medicine, University of Malawi Chikwawa District Hospital, Blantyre, Malawi Zambia St Paul Hospital Nchelenge, Nchelenge District, Zambia Collapse << |
NCT00529620 | Malaria | Phase 3 | Completed | - | Senegal ... more >> Departement de Parasitologie et Mycologie, Universite Cheikh Anta Diop Dakar, Senegal Collapse << |
NCT03697668 | Plasmodium Falciparum Malaria ... more >>(Drug Resistant) Collapse << | Phase 2 | Recruiting | December 31, 2019 | Vietnam ... more >> A Tuc Recruiting Hương Hóa, Quang Tri, Vietnam, 520000 Contact: Tuan A Tran, MD +84982290426 tuanhuonghoa@gmail.com Collapse << |
NCT02083380 | - | - | Completed | - | - |
NCT01222949 | Malaria, Falciparum | Phase 1 | Completed | - | Australia ... more >> CMAX, a division of IDT Australia Limited Adelaide, Australia, SA 5000 Nucleus Network Limited Melbourne, Australia, VIC 3004 Collapse << |
NCT01525511 | Healthy | Phase 1 | Completed | - | Thailand ... more >> Hospital of Tropical Diseases, Faculty of Tropical Medicine, Mahidol University Bangkok, Thailand, 10400 Collapse << |
NCT02431650 | Malaria | Phase 1 Phase 2 | Completed | - | Australia, Queensland ... more >> Q-Pharm Clinics Herston, Queensland, Australia, 4006 Collapse << |
NCT02788864 | Malaria | Phase 4 | Completed | - | Vietnam ... more >> Bu Gia Map Commune Health Station Binh Phuoc, Vietnam, 830000 Collapse << |
NCT02974348 | Drug Resistant Malaria Due to ... more >>Plasmodium Falciparum Collapse << | Phase 3 | Completed | - | Cameroon ... more >> CDC Hospital Tiko, South west, Cameroon, 237 Collapse << |
NCT02575755 | Pregnancy Inf... more >>ections, Plasmodia Drug Kinetics Clinical Efficacy Collapse << | Phase 4 | Unknown | October 2016 | Papua New Guinea ... more >> Papua New Guinea Institute of Medical Research Recruiting Madang, Madang Province, Papua New Guinea, 511 Contact: Brioni R Moore, BSc, PhD (+61) 0466266334 brioni.moore@uwa.edu.au Contact: Leanne J Robinson, BSc, PhD, MPH (+675) 422 2909 robinson@wehi.edu.au Collapse << |
NCT02543086 | Plasmodium Falciparum Malaria | Phase 1 | Terminated | - | Australia, Queensland ... more >> Novartis Investigative Site Brisbane, Queensland, Australia, 4006 Collapse << |
NCT01930331 | Plasmodium Falciparum ... more >> Malaria, Falciparum Collapse << | Phase 4 | Completed | - | Tanzania ... more >> Ifakara Health Institute Bagamoyo, Tanzania, 74 Collapse << |
NCT02461186 | Uncomplicated Falciparum Malar... more >>ia Artemisinin-resistant Collapse << | Phase 2 Phase 3 | Withdrawn(Change of the study ... more >>site due to the current political climate in Myanmar.) Collapse << | June 2017 | - |
NCT03542149 | Malaria | Phase 1 | Recruiting | July 15, 2019 | Australia, Queensland ... more >> Q-Pharm Recruiting Herston, Queensland, Australia, 4006 Contact: Brenda Cerqueira, MSc +61 (0) 439 726 233 B.Cerqueira@qpharm.com.au Contact: Priscila White, MSc +61 (0) 439 726 233 P.White@qpharm.com.au Collapse << |
NCT01853475 | Malaria | Phase 1 | Completed | - | United Kingdom ... more >> Richmond Pharmacology Limited Croyden, London, United Kingdom, CR7 7YE Collapse << |
NCT01853475 | - | - | Completed | - | - |
NCT02387580 | - | - | Completed | - | - |
NCT02083406 | Malaria | Phase 1 | Completed | - | United Kingdom ... more >> Quotient Clinical Nottingham, Nottinghamshire, United Kingdom, NG11 6JS Collapse << |
NCT02083406 | - | - | Completed | - | - |
NCT02431637 | Malaria | Phase 1 | Completed | - | Australia, Queensland ... more >> Q-Pharm Clinics Herston, Queensland, Australia, 4006 Collapse << |
NCT01958619 | Malaria | Phase 1 | Completed | - | United Kingdom ... more >> Richmond Pharmacology Ltd. Croydon, London, United Kingdom, CR7 7YE Collapse << |
NCT02198807 | Oral Treatment of Acute Uncomp... more >>licated Plasmodium Falciparum Malaria Collapse << | Phase 2 | Unknown | December 2015 | - |
NCT01958619 | - | - | Completed | - | - |
NCT02387580 | Malaria | Phase 1 | Completed | - | United Kingdom ... more >> Quotient Clinical Nottingham, Nottinghamshire, United Kingdom, NG11 6JS Collapse << |
NCT01222962 | Malaria, Falciparum | Phase 1 | Completed | - | Australia ... more >> CMAX, a division of IDT Australia Limited Adelaide, Australia, SA 5000 Collapse << |
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