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CAS No.: 1453848-26-4
Synonyms: GDC-0994;RG7842;GDC-994
GDC-0994 is highly selective for ERK1 and ERK2, with IC50 of 1.1 nM and 0.3 nM, respectively.
规格 | 价格 | 促销价格 | 库存 | 数量 |
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生物活性
靶点 | ERK1 IC50:1.1nM | ERK2 IC50:0.3nM |
动物研究 | |
剂量 | Mice: 60 mg/kg[2] (p.o.) |
给药途径 | p.o. |
NCT号 | 适应症或疾病 | 临床期 | 招募状态 | 预计完成时间 | 地点 |
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NCT02457793 | Non-Small Cell Lung Cancer, Me... more >>tastatic Colorectal Cancer, Metastatic Non Small Cell Lung Cancer, Metastatic Cancers, Melanoma Collapse << | Phase 1 | Completed | - | United States, Colorado ... more >> University of Colorado Aurora, Colorado, United States, 80045-2517 United States, Connecticut Yale Cancer Center New Haven, Connecticut, United States, 06520 United States, Massachusetts Dana Farber Cancer Institute Boston, Massachusetts, United States, 02215 United States, Missouri Washington University School of Medicine Saint Louis, Missouri, United States, 63110 United States, Tennessee Sarah Cannon Research Institute Nashville, Tennessee, United States, 37203 Collapse << |
NCT01875705 | Solid Tumor | Phase 1 | Completed | - | United States, Connecticut ... more >> Yale Cancer Center; Medical Oncology New Haven, Connecticut, United States, 06520 United States, Michigan Karmanos Can Inst Detroit, Michigan, United States, 48201 United States, Tennessee Sarah Cannon Research Inst. Nashville, Tennessee, United States, 37203 France Institut Gustave Roussy; Departement Oncologie Medicale Villejuif, France, 94805 Collapse << |
NCT02457793 | - | - | Completed | - | - |
实验方案
技术信息
CAS号 | 1453848-26-4 | 储存条件 |
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分子式 | C21H18ClFN6O2 | 运输 | 蓝冰 | |||||||||||
分子量 | 440.86 | 别名 | GDC-0994;RG7842;GDC-994 | |||||||||||
溶解度 |
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动物实验配方 |
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