CAS No.: 89786-04-9
Tazobactam Acid/他唑巴坦 Catalog No. CSN16641
Synonyms: CL-298741;YTR-830H;Tazobactam Acid
Tazobactam is a penicillin-derived antibacterial working by inhibiting the action of bacterial β-lactamases.
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纯度 & 质量文件
批次:
靶点选择性
生物活性
- 描述
- 临床研究
NCT号 适应症或疾病 临床期 招募状态 预计完成时间 地点 NCT03120663 - - Recruiting September 30, 2018 Belgium ... more >> University Hospitals Leuven Recruiting Leuven, Belgium, 3000 Contact: Peter Declercq, PharmD. +321642340 peter.declercq@uzleuven.be Principal Investigator: Peter Declercq, PharmD. Collapse << NCT02306928 - - Completed - Denmark ... more >> Department of anesthesiology and intensive care, Aarhus University Hospital Aarhus N, Denmark, 8200 Collapse << NCT02473263 Severe Septic Syndrome (Severe... more >> Sepsis and Septic Shock) Diagnosed and Treated by Mobile Intensive Care Unit Collapse << Phase 3 Recruiting March 2019 France ... more >> Anesthesiology, Intensive Care Unit and emergency department - Necker Hospital Recruiting Paris, France, 75015 Contact: Romain Jouffroy, MD +33 1 44 49 54 07 romain.jouffroy@nck.aphp.fr Collapse << - 更多
- 参考文献
- [1] Melchers MJ, Mavridou E, et al. Plasma and epithelial lining fluid pharmacokinetics of ceftolozane and tazobactam alone and in combination in mice. Antimicrob Agents Chemother. 2015;59(6):3373-6.
- [2] Bryson HM, Brogden RN. Piperacillin/tazobactam. A review of its antibacterial activity, pharmacokinetic properties and therapeutic potential. Drugs. 1994 Mar;47(3):506-35.
- [3] Larson KB, Patel YT, Willavize S, et al. Ceftolozane-Tazobactam Population Pharmacokinetics and Dose Selection for Further Clinical Evaluation in Pediatric Patients with Complicated Urinary Tract or Complicated Intra-abdominal Infections. Antimicrob Agents Chemother. 2019;63(6):e02578-18. Published 2019 May 24
- [4] Beaulieu C, Kurczewski L, Yajnik V. Cefepime challenge after piperacillin/tazobactam-induced thrombocytopenia. J Thromb Thrombolysis. 2019;48(1):167–170
- [5] Kresken M, Körber-Irrgang B, Korte-Berwanger M, et al. Dissemination of carbapenem-resistant Pseudomonas aeruginosa isolates and their susceptibilities to ceftolozane-tazobactam in Germany [published online ahead of print, 2020 Apr 20]. Int J Antimicrob Agents. 2020;105959
实验方案
- 计算器
- 储存液制备
技术信息
| CAS号 | 89786-04-9 | 储存条件 |
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| 分子式 | C10H12N4O5S | 运输 | 蓝冰 | |||||||
| 分子量 | 300.29 | 别名 | CL-298741;YTR-830H;Tazobactam Acid;YTR-830;AC-7620;DB-01606;他唑巴坦;三唑巴坦;他唑巴坦酸 | |||||||
| 溶解度 |
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动物实验配方 |
| NCT号 | 适应症或疾病 | 临床期 | 招募状态 | 预计完成时间 | 地点 |
|---|
| NCT03120663 | - | - | Recruiting | September 30, 2018 | Belgium ... more >> University Hospitals Leuven Recruiting Leuven, Belgium, 3000 Contact: Peter Declercq, PharmD. +321642340 peter.declercq@uzleuven.be Principal Investigator: Peter Declercq, PharmD. Collapse << |
| NCT02306928 | - | - | Completed | - | Denmark ... more >> Department of anesthesiology and intensive care, Aarhus University Hospital Aarhus N, Denmark, 8200 Collapse << |
| NCT02473263 | Severe Septic Syndrome (Severe... more >> Sepsis and Septic Shock) Diagnosed and Treated by Mobile Intensive Care Unit Collapse << | Phase 3 | Recruiting | March 2019 | France ... more >> Anesthesiology, Intensive Care Unit and emergency department - Necker Hospital Recruiting Paris, France, 75015 Contact: Romain Jouffroy, MD +33 1 44 49 54 07 romain.jouffroy@nck.aphp.fr Collapse << |
| NCT02306928 | - | - | Completed | - | - |
| NCT00167960 | - | - | Completed | - | Korea, Republic of ... more >> Incheon, Korea, Republic of, 405-760 Ulsan, Korea, Republic of, 682-714 Collapse << |
| NCT02463747 | Fever Febrile... more >> Neutropenia Collapse << | Phase 4 | Unknown | July 2017 | Israel ... more >> Tel-Aviv Sourasky Medicak center / BMT Unit Not yet recruiting Tel-Aviv, Israel, 6423906 Contact: Ron Ram, MD +972-3-6974138 ronr@tlvmc.gov.il Contact: Shachar Porat, B.Sc. +972-3-6972428 shacharp@tlvmc.gov.il Collapse << |
| NCT03159754 | Appendicitis ... more >>Perforated Appendicitis Ruptured Appendicitis Complicated Appendicitis Collapse << | Not Applicable | Recruiting | June 30, 2022 | United States, Michigan ... more >> University of Michigan Recruiting Ann Arbor, Michigan, United States, 48109 Contact: Sarah E. Fox, B.A. 734-232-8005 sarasort@med.umich.edu Collapse << |
| NCT02242006 | - | - | Unknown | - | Canada, Ontario ... more >> The Ottawa Hospital Not yet recruiting Ottawa, Ontario, Canada, K1H 8L6 Contact: Salmaan Kanji skanji@toh.on.ca Collapse << |
| NCT02991937 | Appendicitis | Not Applicable | Recruiting | May 2020 | United States, New York ... more >> New York University Recruiting New York, New York, United States, 10016 Contact: Akila Ramaraj Akila.Ramaraj@med.nyu.edu Principal Investigator: Jason Fisher, ND Collapse << |
| NCT02840136 | Cystic Fibrosis | Not Applicable | Suspended(Lack of staff) | December 2020 | Belgium ... more >> Ghent University Ghent, Oost-Vlaanderen, Belgium, 9000 Collapse << |
| NCT02533609 | - | - | Active, not recruiting | December 2019 | Germany ... more >> Prof. Kindgen-Milles Duesseldorf, Germany, 40225 Collapse << |
| NCT01788449 | - | - | Completed | - | - |
| NCT01793012 | - | - | Completed | - | Germany ... more >> Department of Anaesthesiology of the University Hospital of Munich Munich, Germany, 81377 Collapse << |
| NCT03583749 | - | - | Not yet recruiting | October 20, 2020 | France ... more >> CHU de Bordeaux Not yet recruiting Bordeaux, France, 33000 Contact: Claire ROUBAUD-BAUDRON, MD +335 57 65 66 10 claire.roubaud@chu-bordeaux.fr Principal Investigator: Claire ROUBAUD-BAUDRON, MD Hospital Métropole Savoie Chambéry, France, 73000 CHU de Grenoble Alpes Not yet recruiting Grenoble, France, 38700 Contact: Gaëtan GAVAZZI, MD, PhD +334 76 76 57 97 ggavazzi@chu-grenoble.fr Hospices Civils de Lyon Not yet recruiting Lyon, France, 69000 Contact: Tristan FERRY, MD, PhD +334 72 07 11 07 tristan.ferry@chu-lyon.fr Principal Investigator: Tristan FERRY, MD, PhD University Hospital, Poitiers Poitiers, France, 86021 Collapse << |
| NCT00044928 | Bacterial Infections | Phase 4 | Completed | - | - |
| NCT01983787 | - | - | Completed | - | - |
| NCT03622008 | Antibiotics Causing Adverse Ef... more >>fects in Therapeutic Use Collapse << | Phase 1 | Completed | - | United States, Wisconsin ... more >> Spaulding Clinical Research West Bend, Wisconsin, United States, 53095 Collapse << |
| NCT02611271 | - | - | Recruiting | July 2019 | Germany ... more >> Interdisziplinäre Intensivstation ZOM 1, UKD Recruiting Duesseldorf, Germany, 40225 Contact: Detlef Kindgen-Milles, Prof. 0049 211 81 ext 07047 Kindgen-Milles@med.uni-duesseldorf.de Collapse << |
| NCT03376529 | Healthy Volunteers | Phase 1 | Completed | - | United Kingdom ... more >> Simbec Research, Ltd. Merthyr Tydfil,, Mid Glamorgan, United Kingdom, CF48 4DR Collapse << |
| NCT01983787 | - | - | Completed | - | Denmark ... more >> Department of Infectious Diseases, Aarhus University Hospital Aarhus, Aarhus N, Denmark, 8220 Collapse << |
| NCT01027832 | Tracheobronchitis | Phase 2 Phase 3 | Unknown | September 2011 | Israel ... more >> Assaf Harofe MC Recruiting Beer Yakov, Zerifin, Israel, 70300 Contact: Arie Soroksky, M.D. 972-8-9779320 soroksky@gmail.com Principal Investigator: Arie Soroksky, M.D. Collapse << |
| NCT02795793 | Acute Focal Appendicitis ... more >> Appendicitis Collapse << | Not Applicable | Recruiting | December 2019 | Australia, New South Wales ... more >> Sydney Children's Hospital Recruiting Randwick, New South Wales, Australia, 2031 Contact: Susan Adams, MBBS Principal Investigator: Susan Adams, MBBS The Children's Hospital at Westmead Not yet recruiting Westmead, New South Wales, Australia, 2145 Contact: Jonathon Karpewlosky, MBBCh Principal Investigator: Jonathon Karpelowsky, MBBCh Collapse << |
| NCT02609646 | - | - | Recruiting | December 2019 | Italy ... more >> Ospedale Maurizio Bufalini, UO Anestesia Terapia Intensiva Recruiting Cesena, Emilia Romagna, Italy, 47023 Contact: Marco Benni, MD Principal Investigator: Marco Benni, MD Ospedale S. Giovanni di Dio ASL 10, Servizio Anestesia e Rianimazione Not yet recruiting Firenze, FI, Italy, 50143 Principal Investigator: Valerio Mangani, MD Presidio Ospedaliero "San Leopoldo Mandic" Recruiting Merate, Lecco, Italy, 23807 Contact: Davide Guzzon, MD Principal Investigator: Davide Guzzon, MD Ospedale A. Manzoni, U.O. Anestesia e Rianimazione 1 Recruiting Lecco, Lombardia, Italy, 23900 Contact: Giuseppe Nattino, MD Principal Investigator: Giuseppe Nattino, MD Sub-Investigator: Rita Ciceri, MD Ospedale San Giovanni Bosco, Servizio Anestesia e Rianimazione B-DEA Recruiting Torino, Piemonte, Italy, 10148 Contact: Daniela Silengo, MD Principal Investigator: Daniela Silengo, MD Fondazione IRCCS Policlinico San Matteo Recruiting Pavia, PV, Italy, 27100 Contact: Alessandro Amatu, MD Principal Investigator: Alessandro Amatu, MD Ospedale Giovanni Paolo II Not yet recruiting Olbia, Sardegna, Italy, 07026 Contact: Maria Giovanna Dessena, MD 0789552984 Principal Investigator: Maria Giovanna Dessena, MD Ospedale del Mugello Recruiting Borgo San Lorenzo, Toscana, Italy, 50032 Contact: Rossella Carlà, MD Principal Investigator: Rossella Carlà, MD Ospedale Santa Maria Nuova, Anestesia e Rianimazione Recruiting Firenze, Toscana, Italy, 50122 Contact: Massimo Barattini, MD Principal Investigator: Massimo Barattini, MD Ospedale Alta Val d'Elsa, Terapia Intensiva Not yet recruiting Poggibonsi, Toscana, Italy, 53036 Contact: Andrea Veneziani, MD Principal Investigator: Andrea Veneziani, MD Collapse << |
| NCT03765645 | Antibiotic Prophylaxis ... more >> Postoperative Infection Collapse << | Not Applicable | Recruiting | December 2019 | India ... more >> ILBS Recruiting New Delhi, Delhi, India, 110070 Contact: Sahil Gupta, MBBS, MS +91-7835056201 sahil.self@gmail.com Collapse << |
| NCT01994993 | Complicated Intra Abdominal In... more >>fections Collapse << | Phase 2 Phase 3 | Completed | - | - |
| NCT01994993 | - | - | Completed | - | - |
| NCT02709382 | Renal Impairment | Phase 1 | Completed | - | United States, Florida ... more >> University of Miami,Division of Clinical Pharmacology Miami, Florida, United States, 33136 Collapse << |
| NCT03262142 | COPD Respirat... more >>ory Tract Infections Pseudomonas Aeruginosa Collapse << | Phase 4 | Recruiting | December 2021 | Denmark ... more >> Herlev and Gentofte Hospital Recruiting Hellerup, Copenhagen, Denmark, 2900 Nordsjællands Hospital Recruiting Hillerød, Denmark Collapse << |
| NCT03019965 | Sepsis | Not Applicable | Recruiting | February 2019 | Mexico ... more >> Hospital Infantil de México Federico Gómez Recruiting Mexico, Distrito Federal, Mexico, 06720 Contact: Rodolfo Norberto Jiménez 52(55)55-88-7238 ext 2331 dr.jimenezjuarez@gmail.com Contact: Sarbelio Moreno 52(55)52-28-9917 ext 2331 sarbelio.infecto@gmail.com Sub-Investigator: Fortino Solórzano Instituto Mexicano del Seguro Social Recruiting Mexico, Distrito Federal, Mexico, 06720 Contact: José Guillermo Vázquez 52(55)56-27-6900 ext 22462 vazguill@aol.com Contact: Ma. Guadalupe Miranda 52(55)56-27-6900 ext 22507 uepidemiologia@live.com.mx Collapse << |
| NCT03078010 | Intestinal Microbiome ... more >> Febrile Neutropenia Collapse << | Phase 2 | Recruiting | February 2019 | United States, New York ... more >> Memorial Sloan Kettering Cancer Center Recruiting New York, New York, United States, 10065 Contact: Boglarka Gyurkocza, MD 212-639-2860 Contact: Susan Seo, MD 212-639-3151 Collapse << |
| NCT03140826 | - | - | Recruiting | July 2020 | Germany ... more >> University Hospital Cologne Recruiting Cologne, Germany, 50935 Contact: Maria Vehreschild, Dr Institute of Medical Microbiology and Hygiene, University Hospital of Tuebingen Recruiting Tuebingen, Germany, 72076 Contact: Matthias Willmann, MD +49 7071 29-81527 matthias.willmann@med.uni-tuebingen.de Collapse << |
| NCT00488189 | Bacterial Infections | Phase 4 | Completed | - | China, Beijing ... more >> Beijing, Beijing, China, 100037 Collapse << |
| NCT03036826 | - | - | Not yet recruiting | June 2021 | Germany ... more >> University Hospital Tuebingen Tuebingen, Germany, 72076 Collapse << |
| NCT00003805 | Bone Marrow Suppression ... more >> Fever, Sweats, and Hot Flashes Infection Leukemia Lymphoma Multiple Myeloma and Plasma Cell Neoplasm Myelodysplastic Syndromes Unspecified Adult Solid Tumor, Protocol Specific Unspecified Childhood Solid Tumor, Protocol Specific Collapse << | Phase 3 | Completed | - | - |
| NCT03630081 | Complicated Urinary Tract Infe... more >>ction Acute Pyelonephritis Collapse << | Phase 3 | Not yet recruiting | November 25, 2019 | - |
| NCT03289351 | Perforated Appendicitis ... more >> Postoperative Infection Collapse << | Not Applicable | Recruiting | May 22, 2018 | United States, Arizona ... more >> Phoenix Children's Hospital Recruiting Phoenix, Arizona, United States, 85016 Contact: Justin Lee, MD 602-933-7007 jlee8@phoenixchildrens.com Collapse << |
| NCT00229112 | Foot Infections in Diabetic Pa... more >>tients Collapse << | Phase 3 | Completed | - | - |
| NCT00253955 | Pneumonia | Phase 3 | Completed | - | - |
| NCT00414193 | - | - | Completed | - | United States, Pennsylvania ... more >> University of Pittsburgh Medical Center Pittsburgh, Pennsylvania, United States, 15213 Collapse << |
| NCT02191475 | Abdominal Infection | Phase 2 Phase 3 | Unknown | May 2017 | China, Tianjin ... more >> TianjinCIH Recruiting Tianjin, Tianjin, China, 300060 Contact: Wang Donghao, Chief 022-23340123 ext 1021 donghaow@medmail.com.cn Contact: Wang Donghao Donghao, Chief 022-23340123 ext 1021 donghaow@medmail.com.cn Sub-Investigator: Lv Yang, physician Collapse << |
| NCT02581280 | - | - | Unknown | December 2016 | Korea, Republic of ... more >> Division of Cardiology, Department of Internal Medicine, Yonsei University College of Medicine Recruiting Seoul, Korea, Republic of, 03722 Contact: Jin Wi, MD 82-2-2228-8460 caesar@yuhs.ac Collapse << |
| NCT00573521 | - | - | Completed | - | United States, Pennsylvania ... more >> UPMC Pittsburgh, Pennsylvania, United States, 15213 Collapse << |
| NCT01290003 | Neonatal Sepsis | Not Applicable | Completed | - | India ... more >> Kalawati Saran children's Hospital, Lady Hardinge Medical College New Delhi, Delhi, India, 110001 Collapse << |
| NCT02619149 | Cholecystitis, Acute | Phase 3 | Completed | - | Sweden ... more >> Karolinska University Hospital, Center for Digestive Diseases Stockholm, Sweden, 14186 Collapse << |
| NCT03335137 | - | - | Completed | - | Germany ... more >> University Hospital Schleswig-Holstein Lübeck, Schleswig-Holstein, Germany, 23538 Collapse << |
| NCT03217136 | Complicated Intra-Abdominal In... more >>fection Collapse << | Phase 2 | Recruiting | September 6, 2020 | - |
| NCT00236912 | Appendicitis | Phase 4 | Terminated(This study was term... more >>inated due to low enrollment.) Collapse << | - | - |
| NCT00402727 | Abscess Wound... more >> Infection Diabetic Foot Ulcer Collapse << | Phase 3 | Completed | - | - |
| NCT00044746 | Diabetes Mellitus ... more >> Diabetic Foot Collapse << | Phase 4 | Completed | - | - |
| NCT00195533 | - | - | Completed | - | Spain ... more >> Alcalá de Henares, Spain Alcira, Spain Barcelona, Spain Castellon, Spain Coruña, Spain Madrid, Spain Salamanca, Spain Tarragona, Spain Tenerife, Spain Valencia, Spain Valladolid, Spain Zaragoza, Spain Collapse << |
| NCT00402727 | - | - | Completed | - | - |
| NCT02493764 | Bacterial Pneumonia | Phase 3 | Recruiting | May 31, 2019 | - |
| NCT00924742 | Healthy | Not Applicable | Completed | - | - |
| NCT00044759 | Hematologic Neoplasms | Phase 3 | Completed | - | - |
| NCT03687255 | Urinary Tract Infections | Phase 3 | Recruiting | December 30, 2019 | - |
| NCT03583333 | Hospital-Acquired Bacterial Pn... more >>eumonia Ventilator-Associated Bacterial Pneumonia Collapse << | Phase 3 | Recruiting | April 25, 2021 | China, Beijing ... more >> Peking University Third Hospital ( Site 0115) Recruiting Beijing, Beijing, China, 100191 Contact: Study Coordinator +8613910125933 China, Guangdong The First Affiliated Hospital of Guangzhou Medical University ( Site 0123) Recruiting Guangzhou, Guangdong, China, 510120 Contact: Study Coordinator +8613902273260 Guangzhou First People's Hospital ( Site 0101) Recruiting Guangzhou, Guangdong, China, 510180 Contact: Study Coordinator +862081048888 Southern Medical University Nanfang Hospital ( Site 0120) Recruiting Guangzhou, Guangdong, China, 510515 Contact: Study Coordinator +8613119545239 Shenzhen People s Hospital ( Site 0134) Recruiting Shenzhen, Guangdong, China, 518020 Contact: Study Coordinator +8675525533018 China, Jiangsu First Hospital Affiliated to Suzhou University ( Site 0111) Recruiting Suzhou, Jiangsu, China, 215008 Contact: Study Coordinator +8651267780040 Wuxi People's Hospital ( Site 0124) Recruiting Wuxi, Jiangsu, China, 214023 Contact: Study Coordinator +86051085350348 China, Jiangxi Jiangxi Provincial People's Hospital ( Site 0129) Recruiting Nanchang, Jiangxi, China, 330006 Contact: Study Coordinator +8679186895863 The First Affiliated Hospital of Nanchang University ( Site 0132) Recruiting Nanchang, Jiangxi, China, 330006 Contact: Study Coordinator +8613707089183 China, Shanghai Huashan Hospital of Fudan University ( Site 0105) Recruiting Shanghai, Shanghai, China, 200040 Contact: Study Coordinator +8621528899 Shanghai General Hospital ( Site 0125) Recruiting Shanghai, Shanghai, China, 200080 Contact: Study Coordinator 8602163240090 China, Zhejiang The First Affiliated Hospital.Zhejiang University ( Site 0102) Recruiting Hangzhou, Zhejiang, China, 310003 Contact: Study Coordinator +8613505719970 Sir Run Run Shaw Hospital School of Medicine, Zhejiang University ( Site 0110) Recruiting Hangzhou, Zhejiang, China, 310016 Contact: Study Coordinator +86057186006102 The 2nd Affiliated Hospital of Wenzhou Medical University ( Site 0130) Recruiting Wenzhou, Zhejiang, China, 325000 Contact: Study Coordinator +8613857715778 China Aero Space center hospital ( Site 0118) Recruiting Beijing, China, 100049 Contact: Study Coordinator +8613611106725 Beijing Hospital ( Site 0127) Recruiting Beijing, China, 100730 Contact: Study Coordinator +8613701097436 Ruijin Hospital Shanghai Jiao Tong University School of Medicine ( Site 0104) Recruiting Shanghai, China, 200025 Contact: Study Coordinator +8602134186000 Collapse << |
| NCT02508753 | Healthy | Phase 1 | Completed | - | United States, North Dakota ... more >> Cetero Reserach Fargo, North Dakota, United States, 58104 Collapse << |
| NCT00816790 | Septic Shock ... more >>Acute Renal Failure Collapse << | Phase 4 | Terminated(Study stopped becau... more >>se of study personel movement to another institution.) Collapse << | - | Canada, British Columbia ... more >> Royal Columbian Hospital New Westminster, British Columbia, Canada, V3L 3W7 Collapse << |
| NCT03467854 | - | - | Recruiting | March 2019 | United States, New York ... more >> NewYork-Presbyterian Hospital Recruiting New York, New York, United States, 10032 Contact: Amy L Dzierba, PharmD 212-305-5852 ald9012@nyp.org Contact: Daniel Brodie, MD 212-305-9817 hdb5@cumc.columbia.edu Collapse << |
| NCT01198925 | Infectious Disease | Phase 4 | Completed | - | Belgium ... more >> University Hospital Ghent Ghent, Belgium Collapse << |
| NCT00167999 | - | - | Completed | - | Korea, Republic of ... more >> Seoul, Korea, Republic of, 133-792 Collapse << |
| NCT03230838 | Complicated Urinary Tract Infe... more >>ction Pyelonephritis Collapse << | Phase 2 | Recruiting | September 6, 2020 | - |
| NCT00873327 | Sepsis | Phase 1 | Completed | - | United States, Indiana ... more >> Indiana University School of Medicine Indianapolis, Indiana, United States, 46202 United States, Kansas Wesley Medical Center Wichita, Kansas, United States, 67214 United States, Missouri Children's Mercy Hospital Kansas City, Missouri, United States, 64108 United States, North Carolina Duke University Medical Center Durham, North Carolina, United States, 27710 Collapse << |
| NCT03776409 | - | - | Not yet recruiting | December 1, 2019 | China, Shaanxi ... more >> First Affiliated Hospital of Xian Jiaotong University Not yet recruiting Xi'an, Shaanxi, China, 710061 Contact: Yalin Dong, Ph.D Collapse << |
| NCT01714557 | Neutropenia H... more >>ematopoietic Stem Cell Transplantation Collapse << | Not Applicable | Unknown | November 2014 | China, Beijing ... more >> Chinese PLA general hospital Not yet recruiting Beijing, Beijing, China Contact: Wenrong Huang, Doctor huangwr301@yahoo.com.cn Collapse << |
| NCT00195286 | - | - | Completed | - | Spain ... more >> Antequera (Málaga), Spain Avila, Spain Barcelona, Spain Berga (Barcelona), Spain Caceres, Spain Castellón, Spain Ciudad Real, Spain Cuenca, Spain Cádiz, Spain Ferrol, Spain Granada, Spain Jaen, Spain Las Palmas, Spain Lorca (Murcia), Spain Lugo, Spain Lérida, Spain Madrid, Spain Osuna (Sevilla), Spain Palma Mallorca, Spain Pamplona, Spain Pontevedra, Spain Terrasa, Spain Torrelavega, Spain Valencia, Spain Valladolid, Spain Vitoria, Spain Zaragoza, Spain Collapse << |
| NCT00873327 | - | - | Completed | - | - |
| NCT01714570 | Febrile Neutr... more >>openia Hematopoietic Stem Cell Transplantation Collapse << | Not Applicable | Completed | - | China, Beijing ... more >> Chinese PLA general hospital Beijing, Beijing, China, 100853 Collapse << |
| NCT00389987 | Complicated Intra-Abdominal In... more >>fections Collapse << | Phase 3 | Completed | - | - |
| NCT00629135 | Abscess, Intra-Abdominal | Phase 3 | Completed | - | Germany ... more >> Medical School Hannover Hannover, Germany, 30625 Collapse << |
| NCT03581370 | Ventilator-associated Pneumoni... more >>a Collapse << | Phase 3 | Not yet recruiting | July 2021 | France ... more >> Service Réanimation Polyvalente - CHU Rangueil Not yet recruiting Toulouse, France, 31059 Contact: Stéphanie RUIZ, MD 05 61 32 44 64 ext 33 Ruiz.stephanie@chu-toulouse.fr Sub-Investigator: Bernard GEORGES, MD Principal Investigator: Stéphanie RUIZ, MD Sub-Investigator: Jean-Marie CONIL, MD Sub-Investigator: David ROUSSET Collapse << |
| NCT01370616 | Infection; Diabetic Foot | Phase 3 | Completed | - | - |
| NCT03006679 | Hospital-Acquired Bacterial Pn... more >>eumonia Ventilator-Associated Bacterial Pneumonia Hospital-Acquired Pneumonia Ventilator-Associated Pneumonia Collapse << | Phase 3 | Not yet recruiting | December 2020 | - |
| NCT02820987 | Septic Shock | Phase 3 | Recruiting | September 1, 2018 | France ... more >> Chu Besancon Recruiting Besançon, France, 25000 Contact: hadrien winiszewski 0673628948 hadrien51@hotmail.com Collapse << |
| NCT01370616 | - | - | Completed | - | - |
| NCT01517815 | Septic Shock | Not Applicable | Completed | - | France ... more >> Saint Eloi Intensive Care Unit - Montpellier University Hospital Montpellier, France, 34295 Collapse << |
| NCT02266706 | Proven or Suspected Gram-negat... more >>ive Bacterial Infection Peri-operative Prophylaxis Collapse << | Phase 1 | Completed | - | - |
| NCT02739997 | Intra-abdominal Infection ... more >> Complicated Intra-abdominal Infection Collapse << | Phase 3 | Completed | - | - |
| NCT01923363 | Obesity | Not Applicable | Completed | - | United States, California ... more >> Loma Linda University Medical Center Loma Linda, California, United States, 92350 Collapse << |
| NCT01923363 | - | - | Completed | - | - |
| NCT03441529 | Healthy | Phase 1 | Completed | - | Belgium ... more >> Clinical Pharmacology Unit Merksem, Belgium, 2170 Collapse << |
| NCT02962934 | - | - | Recruiting | December 2018 | Australia, Queensland ... more >> Royal Brisbane and Women's Hospital Recruiting Brisbane, Queensland, Australia, 4029 Contact: Jason A Roberts, PhD Collapse << |
| NCT02739997 | - | - | Completed | - | - |
| NCT01853982 | Ventilator-Associated Pneumoni... more >>a (VAP) Collapse << | Phase 3 | Terminated(Terminated to focus... more >> on a larger study within the clinical development program.) Collapse << | - | United States, Florida ... more >> Jacksonville, Florida, United States United States, Illinois Chicago, Illinois, United States United States, Maryland Baltimore, Maryland, United States United States, Minnesota Duluth, Minnesota, United States United States, Nebraska Omaha, Nebraska, United States United States, New York Bronx, New York, United States Jamaica, New York, United States United States, Ohio Cleveland, Ohio, United States United States, Oklahoma Oklahoma City, Oklahoma, United States United States, Pennsylvania Abington, Pennsylvania, United States United States, Tennessee Nashville, Tennessee, United States Australia, Queensland Herston, Queensland, Australia Meadowbrook, Queensland, Australia Nambour, Queensland, Australia Southport, Queensland, Australia Woolloongabba, Queensland, Australia New Zealand Auckland, New Zealand Christchurch, New Zealand Wellington, New Zealand Collapse << |
| NCT02166476 | Urinary Tract Infection Compli... more >>cated Acute Pyelonephritis Collapse << | Phase 3 | Completed | - | - |
| NCT00703144 | Diffusive and Convective Clear... more >>ance Body Clearance Piperacillin Tazocilline Concentrations (Cmin) Collapse << | Phase 4 | Completed | - | France ... more >> Service de Néphrologie Toulouse, France, 31059 Collapse << |
| NCT02166476 | - | - | Completed | - | - |
| NCT01853982 | - | - | Terminated(Terminated to focus... more >> on a larger study within the clinical development program.) Collapse << | - | - |
| NCT03671967 | Beta Lactam Resistant Bacteria... more >>l Infection Enterobacteriaceae Infections Bacteremia Collapse << | Phase 4 | Not yet recruiting | April 2024 | - |
| NCT03510351 | - | - | Active, not recruiting | February 28, 2019 | United States, Pennsylvania ... more >> Temple University, School of Pharmacy Philadelphia, Pennsylvania, United States, 19140 Collapse << |
| NCT02728089 | Urinary Tract Infection (UTI) ... more >> Complicated Urinary Tract Infection Pyelonephritis Uncomplicated Pyelonephritis Collapse << | Phase 3 | Completed | - | - |
| NCT02620774 | Diabetes Woun... more >>d Infection Healthy Volunteers Collapse << | Phase 1 | Recruiting | December 2017 | United States, Connecticut ... more >> Hartford Hospital Recruiting Hartford, Connecticut, United States, 06102 Contact: David P Nicolau, PharmD 860-972-3941 david.nicolau@hhchealth.org Contact: Arlinda Carr 860-972-6724 arlinda.carr@hhchealth.org Principal Investigator: David P Nicolau, PharmD Sub-Investigator: Joseph L Kuti, PharmD Sub-Investigator: Ashley Shepard, MD Sub-Investigator: James Nugent, MD Collapse << |
| NCT03738683 | - | - | Not yet recruiting | December 1, 2019 | Netherlands ... more >> Radboud University Medical Center Nijmegen, Gelderland, Netherlands University Medical Centre Utrecht Utrecht, Netherlands Collapse << |
| NCT02728089 | - | - | Completed | - | - |
| NCT02070757 | Nosocomial Pneumonia | Phase 3 | Completed | - | - |
| NCT01147640 | Complicated Intra-abdominal In... more >>fection Collapse << | Phase 2 | Completed | - | - |
| NCT01694069 | Cystic Fibrosis | Phase 4 | Terminated(Recruitment was not... more >> sufficient to complete the study) Collapse << | December 2014 | United States, West Virginia ... more >> West Virginia University Healthcare Morgantown, West Virginia, United States, 26505 Collapse << |
| NCT01147640 | - | - | Completed | - | - |
| NCT01577368 | Pseudomonas Aeruginosa Infecti... more >>on Collapse << | Phase 3 | Completed | - | Spain ... more >> Hospital Universitario Virgen del Rocío Seville, Spain, 41013 Collapse << |
| NCT03748095 | - | - | Not yet recruiting | June 2021 | - |
| NCT02387372 | Critically Ill ... more >> Pneumonia Collapse << | Phase 1 | Completed | - | - |
| NCT02437045 | Bloodstream Infections | Phase 4 | Recruiting | September 2020 | Australia, New South Wales ... more >> John Hunter Hospital Recruiting New Lambton, New South Wales, Australia, 2305 Contact: Joshua Davis, Doctor Joshua.Davis@menzies.edu.au Wollongong Hospital Recruiting Wollongong, New South Wales, Australia Contact: Spiros Miyakis, Doctor smiyakis@uow.edu.au Australia, Queensland Princess Alexandra Hospital Recruiting Brisbane, Queensland, Australia, 4101 Contact: Naomi Runnegar, Doctor Naomi.Runnegar@health.qld.gov.au Royal Brisbane Hospital Recruiting Brisbane, Queensland, Australia, 4170 Contact: David Paterson, Professor david.antibiotics@gmail.com Singapore National University Hospital Singapore Not yet recruiting Singapore, Singapore Contact: Sophia Archula, Doctor sophia@nus.edu.sg Tan Tock Seng Hospital Not yet recruiting Singapore, Singapore Contact: Barnaby Young, Doctor barnaby_young@ttsh.com.sg Collapse << |
| NCT01796717 | Nosocomial Pneumonia | Phase 2 Phase 3 | Unknown | December 2016 | China, Tianjin ... more >> TianjinCIH Recruiting Tianjin, Tianjin, China, 300060 Contact: Wang Donghao, Chief 022-23340123 ext 1021 donghaow@medmail.com.cn Sub-Investigator: Yang Yang, resident Sub-Investigator: lv yang, resident TianjinCIH Recruiting Tianjin, Tianjin, China, 300060 Contact: Wang Donghao, Chief 022-23340123 ext 1021 donghaow@medmail.com.cn Collapse << |
| NCT02176122 | Bloodstream Infections | Phase 4 | Terminated(Secondary to third ... more >>interim analysis by the study DSMB.) Collapse << | - | - |
| NCT03002506 | Burns Pharmac... more >>okinetics Collapse << | Phase 4 | Recruiting | June 2020 | United States, Texas ... more >> University Medical Center Recruiting Lubbock, Texas, United States, 79415 Contact: Ann Purdom, RN 806-775-8585 Ann.Purdom@umchealthsystem.com Collapse << |
| NCT02753946 | - | - | Completed | - | - |
| NCT03485950 | Other Infectious Diseases | Phase 2 | Recruiting | May 2019 | United States, Texas ... more >> University of Texas MD Anderson Cancer Center Recruiting Houston, Texas, United States, 77030 Contact iraad@mdanderson.org Collapse << |
| NCT03269994 | Pancreatic Cancer ... more >> Pancreas Cancer Pancreatic Diseases Collapse << | Phase 3 | Recruiting | August 28, 2019 | United States, California ... more >> UC Davis Comprehensive Cancer Center Recruiting Sacramento, California, United States, 95817 Contact: Sepideh Gholami, MD 800-282-3284 United States, Georgia Emory University School of Medicine Recruiting Atlanta, Georgia, United States, 30322 Contact: Shishir Maithel, MD 404-778-5777 United States, Indiana Indiana University Recruiting Indianapolis, Indiana, United States, 46202 Contact: Michael House, MD 317-944-0113 United States, New Jersey Memoral Sloan Kettering Basking Ridge Recruiting Basking Ridge, New Jersey, United States, 07920 Contact: Michael D'Angelica, MD 212-639-3226 United States, New York Memorial Sloan Kettering Cancer Center 1275 York Avenue Recruiting New York, New York, United States, 10065 Contact: Michael D'Angelica, MD 212-639-3226 Principal Investigator: Michael D'Angelica, MD United States, Pennsylvania Thomas Jefferson University Hospital Recruiting Philadelphia, Pennsylvania, United States, 19107 Contact: Harish Lavu, MD 215-955-6702 Principal Investigator: Harish Lavu, MD United States, Tennessee Baptist Memorial Healthcare Recruiting Memphis, Tennessee, United States, 38120 Contact: Stephen Behrman, MD 901-226-5957 United States, Washington University of Washington School of Medicine Recruiting Seattle, Washington, United States, 98109 Contact: Dominic Sanford, MD 314-362-8020 Canada, Ontario Hamilton Health Sciences Center (Juravinski Hospital) Recruiting Hamilton, Ontario, Canada Contact: Pablo Serrano, MD 905.521.2100 Collapse << |
| NCT02730624 | Early Phase of Severe Sepsis a... more >>nd Septic Shock Collapse << | Phase 4 | Completed | - | Thailand ... more >> Division of Clinical Pharmacology, Department of Medicine, Faculty of Medicine, Prince of Songkla University Hat Yai, Songkla, Thailand, 90110 Collapse << |
| NCT02466438 | Infection | Phase 1 | Recruiting | December 2018 | Canada, Quebec ... more >> St. Justine's Hospital Recruiting Montreal, Quebec, Canada, H3T 1C5 Contact: Julie Autmizguine, MD, MHS 514 345-4931 ext 5631 julie.autmizguine@umontreal.ca Contact: Mariana Dumitrascu, MD 1514 345-4931 ext 6648 mariana.dumitrascu@recherche-ste-justine.qc.ca Sub-Investigator: Catherine Litalien, MD, PhD Sub-Investigator: Yves Théoret, B. Pharm., PhD Sub-Investigator: Denis Lebel, B. Pharm. Sub-Investigator: Céline Thibault, MD Collapse << |
| NCT02753946 | Urinary Tract Infection Sympto... more >>matic Acute Pyelonephritis Urinary Tract Infection Complicated Collapse << | Phase 2 Phase 3 | Completed | - | - |
| NCT03309657 | Pharmacokinetics | Phase 1 Phase 2 | Not yet recruiting | December 2020 | - |
| NCT02421120 | - | - | Completed | - | - |
| NCT02421120 | Cystic Fibrosis ... more >> Cystic Fibrosis Pulmonary Exacerbation Pseudomonas Aeruginosa Infection Collapse << | Phase 4 | Completed | - | United States, Connecticut ... more >> Hartford Hospital Hartford, Connecticut, United States, 06102 United States, Indiana Riley Hospital for Children at Indiana University Health Indianapolis, Indiana, United States, 46202 United States, North Carolina University of North Carolina Medical Center Chapel Hill, North Carolina, United States, 27599 United States, Pennsylvania St. Christopher's Hospital for Children Philadelphia, Pennsylvania, United States, 19134 Collapse << |
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